Repository navigation
NTR: add sympathoblast (CL_9900001) - #3810
Open
ai4c-agent[bot] wants to merge 1 commit into
Open
ai4c-agent[bot] wants to merge 1 commit into
ai4c-agent[bot] wants to merge 1 commit into
Conversation
Adds a new term 'sympathoblast' as a committed neural crest-derived neuroblast precursor of postganglionic sympathetic neurons. Modeled as a subclass of neural crest derived neuroblast (CL_0002676) with a develops_into (RO_0002203) relation to sympathetic neuron (CL_0011103). - Definition and synonym 'sympathetic neuroblast' are cited to Edens et al., Nature 2024 (PMID:38632395), which uses the term in a modern developmental and evolutionary context. - Uses the temporary CL_99xxxxx ID range (per idrange:81) pending a permanent ID assignment on merge. - The request on issue #3809 omitted parent, definition and ORCID; this draft is based on established developmental-biology usage and is open for the submitter to refine. Addresses #3809 Co-Authored-By: Claude Opus 4.7 <noreply@anthropic.com>
This branch has not been deployed
This file contains hidden or bidirectional Unicode text that may be interpreted or compiled differently than what appears below. To review, open the file in an editor that reveals hidden Unicode characters.
Learn more about bidirectional Unicode characters
Sign up for free
to join this conversation on GitHub.
Already have an account?
Sign in to comment
Add this suggestion to a batch that can be applied as a single commit.This suggestion is invalid because no changes were made to the code.Suggestions cannot be applied while the pull request is closed.Suggestions cannot be applied while viewing a subset of changes.Only one suggestion per line can be applied in a batch.Add this suggestion to a batch that can be applied as a single commit.Applying suggestions on deleted lines is not supported.You must change the existing code in this line in order to create a valid suggestion.Outdated suggestions cannot be applied.This suggestion has been applied or marked resolved.Suggestions cannot be applied from pending reviews.Suggestions cannot be applied on multi-line comments.Suggestions cannot be applied while the pull request is queued to merge.Suggestion cannot be applied right now. Please check back later.
Closes #3809
Summary
Adds a new term sympathoblast (temporary ID
CL_9900001) as the developmental precursor of postganglionic sympathetic neurons.Definition
Notes to reviewer
The NTR form on #3809 was submitted with only the preferred label — no definition, parent, anatomy, references, or ORCID were provided. The term is modeled from established developmental-biology usage and the term is cited to a modern, specific reference (Edens et al., Nature 2024). Please confirm or amend:
part_ofto an UBERON structure has been added, since sympathoblasts are migratory and transient. If a canonical location (e.g. developing sympathetic ganglion) is preferred, this can be added.terms:contributoraxiom.Test plan
robot convertonsrc/ontology/cl-edit.owl— passes🤖 Generated by @ai4c-agent
claude-opus-4-7🤖 Generated with Claude Code