This repository contains code used for data analysis in
Austin Graves, Richard Roth, Han Tan, Qianwen Zhu, Alexei Bygrave, Elena Lopez-Ortega, Alina Spiegel, Ingie Hong, Richard Johnson, Joshua Vogelstein, Daniel Tward, Michael Miller, Richard Huganir "Visualizing synaptic plasticity in vivo by large-scale imaging of endogenous AMPA receptors" Biorxiv, 2020.
Synapses are detected based on local measures of shape and brightness.
Accuracy is quantified by comparing synapses segmented from more than one method.
Intensity measures are quantified in each synapse to describe population behaviour.