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example_config.yaml
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#-------------------------------------------------------------------------#
#-------------------------- TOBIAS input data ----------------------------#
#-------------------------------------------------------------------------#
data:
Bcell: [data/Bcell.bam] #list of .bam-files
Tcell: [data/Tcell_day*.bam] #list of .bam-files
run_info:
organism: human #mouse/human/zebrafish (used for macs to set "--gsize"; alternatively, set --gsize in macs parameters below)
fasta: data/genome.fa.gz #.fasta-file containing organism genome. NOTE: must be uncompressed .fa or bgzip compressed compatible with samtools
blacklist: data/blacklist.bed #.bed-file containing blacklisted regions
gtf: data/genes.gtf #.gtf-file for annotation of peaks. NOTE: must be uncompressed .gtf
motifs: data/individual_motifs/* #motifs (directory with files or individual files in MEME/JASPAR/PFM format)
output: test_output #output directory
#peaks: data/merged_peaks_annotated.bed #optional; pre-calculated annotated peaks
#peaks_header: data/merged_peaks_annotated_header.txt #optional; header for pre-calculated annotated peaks
#Flags for parts of pipeline to include/exclude (all are True by default)
flags:
plot_comparison: True #True/False
plot_correction: True
plot_venn: True
coverage: True
wilson: True
#-------------------------------------------------------------------------#
#----------------------- Default module parameters -----------------------#
#-------------------------------------------------------------------------#
macs: "--nomodel --shift -100 --extsize 200 --broad"
atacorrect: ""
footprinting: ""
bindetect: ""