Skip to content
New issue

Have a question about this project? Sign up for a free GitHub account to open an issue and contact its maintainers and the community.

By clicking “Sign up for GitHub”, you agree to our terms of service and privacy statement. We’ll occasionally send you account related emails.

Already on GitHub? Sign in to your account

Develop #14

Open
wants to merge 36 commits into
base: master
Choose a base branch
from
Open
Show file tree
Hide file tree
Changes from all commits
Commits
Show all changes
36 commits
Select commit Hold shift + click to select a range
4e7f402
test_script
arnabmutsuddy Sep 1, 2022
dc374d5
createModel_dev notebook added
arnabmutsuddy Sep 1, 2022
f2b1f99
createModel_dev, input file reading
arnabmutsuddy Sep 1, 2022
2fd27a8
createModel_dev added to testscript1
arnabmutsuddy Sep 2, 2022
6b59930
initiated testModel notebook
arnabmutsuddy Sep 5, 2022
122aa0b
added o4a build code
arnabmutsuddy Sep 5, 2022
8c46baf
deleted untitled notebook
arnabmutsuddy Sep 5, 2022
3c552e9
Merge pull request #13 from arnabmutsuddy/develop
cerdem12 Sep 5, 2022
b1c3d09
removed old compiled files
arnabmutsuddy Sep 5, 2022
6ab70a8
o4a buildcode added
arnabmutsuddy Sep 12, 2022
c144431
o4a buildcode added
arnabmutsuddy Sep 12, 2022
129376d
o4a bulidcode omicsdata input fixed and tested
arnabmutsuddy Sep 12, 2022
9c72eb0
New runsparced module added and tested
arnabmutsuddy Sep 12, 2022
7174e34
fixed input file handling
arnabmutsuddy Sep 13, 2022
77f6937
hardcoded compartment volumes removed from ratelaws
arnabmutsuddy Sep 14, 2022
b662e33
compiled models cleared
arnabmutsuddy Sep 14, 2022
a11522b
compiled model cleared
arnabmutsuddy Sep 14, 2022
861e185
compiled model cleared
arnabmutsuddy Sep 14, 2022
ec9c112
Merge branch 'dev-comps' into develop
arnabmutsuddy Sep 14, 2022
177b6d5
removed genes input
arnabmutsuddy Sep 14, 2022
c693939
genes input removed
arnabmutsuddy Sep 14, 2022
a2b25e9
removed unused files
arnabmutsuddy Sep 15, 2022
b9add41
old RunSPARCED module deleted
arnabmutsuddy Sep 15, 2022
4041abe
deleted old comments
arnabmutsuddy Sep 16, 2022
a0c08ed
fixed typos
arnabmutsuddy Sep 16, 2022
a0f433d
Merge pull request #15 from arnabmutsuddy/develop
cerdem12 Sep 16, 2022
ce694df
deleted unused files
arnabmutsuddy Sep 16, 2022
30ab795
deleted compartments.txt from jupyter-notebooks
arnabmutsuddy Sep 16, 2022
f804caf
readme restored
arnabmutsuddy Sep 16, 2022
633ccab
Merge pull request #16 from arnabmutsuddy/develop
cerdem12 Sep 19, 2022
72e668b
clean up
arnabmutsuddy Oct 2, 2022
d739706
Merge pull request #17 from arnabmutsuddy/develop
arnabmutsuddy Oct 2, 2022
43f7fbe
'cleanup/comments'
arnabmutsuddy Oct 7, 2022
5dc11fa
Merge pull request #23 from arnabmutsuddy/develop
arnabmutsuddy Oct 7, 2022
37bf314
cleanup
arnabmutsuddy Oct 7, 2022
5cd6df7
Merge pull request #24 from arnabmutsuddy/develop
arnabmutsuddy Oct 7, 2022
File filter

Filter by extension

Filter by extension


Conversations
Failed to load comments.
Loading
Jump to
Jump to file
Failed to load files.
Loading
Diff view
Diff view
1,442 changes: 1,442 additions & 0 deletions Demo/GrowthStim_G_0.txt

Large diffs are not rendered by default.

1,442 changes: 1,442 additions & 0 deletions Demo/GrowthStim_S_0.txt

Large diffs are not rendered by default.

15 changes: 14 additions & 1 deletion Demo/Readme.md
Original file line number Diff line number Diff line change
Expand Up @@ -5,7 +5,20 @@ The pre-simulated data are also given (GrowthStim_S_demo.txt and GrowthStim_G_de

## createModel notebook:

- This notebook is already run and the model instance (AMICI required) files are saved in the `SPARCED` subfolder. Users can run the notebook again, with a new model file name to compare to our model provided here.
- This notebook builds the 'SPARCED' hybrid model from the given input files. This notebook is already run and the model instance (AMICI required) files are saved in the `SPARCED` subfolder. Users can run the notebook again, with a new model file name to compare to our model provided here.

## createModel_o4a notebook:

- This notebook has functionality analogous to the createModel notebook, for the integrated-SBML version of 'SPARCED' model. Compiled model files are saved in the 'SPARCEDo4a_v1' folder.

## testModel notebook:

- This notebook imports and tests both 'Hybrid' and 'Integrated-SBML' versions of the 'SPARCED' model and draws comparison plots to demonstrate accuracy of outputs. The user needs to make sure both versions of the model have been already built using the above 'createModel' scripts and current version of AMICI available in the environment before this script can be run.

### Simulation conditions:
- Stimulate with ligands EGF = 1nM, HGF = 0.005nM
- 72 hours of simulation
- Deterministic simulation mode (flagD=1)

## runModel notebook:

Expand Down
4,868 changes: 2,434 additions & 2,434 deletions Demo/SPARCED.txt

Large diffs are not rendered by default.

Loading