Balanced Cell Group Comparisons #19
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- Some cell types are much more abundant than others. - Some patients have many more cells than others. It also switches from a moderated t-test to the similar Cohen's d implemented in C++ for speed in scran_markers. This also avoids QR matrix decomposition and matrix inversion, which linear modelling does.
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This update addresses the cases skewed marker gene ranking of:
It also switches from a moderated t-test to the similar Cohen's d implemented in C++ for speed in scran_markers. This also avoids QR matrix decomposition and matrix inversion, which linear modelling does.
Dependency
scrapper package is not yet in Bioconductor. So, this change should not be merged before then.