Metzger et al. 2023. Analysis scripts for fitting ordinal regression models to characterize genetic architecture of steroid receptor DBDs.
Initial and intermediate data files can be found at dryad https://doi.org/10.5061/dryad.jsxksn0hk.
Functions.R contains new functions developed for fitting large ordinal regression models using sparse matrices 01.Decompose.R contains the data preprocessing, model fits, and analysis of the effects 03.Network.R contains additional analysis of network properties for functional genotypes under different models 04.Simulation.R contains evolutionary simulations over different networks under different evolutionary conditions for each model