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4 changes: 2 additions & 2 deletions .nf-core.yml
Original file line number Diff line number Diff line change
Expand Up @@ -30,7 +30,7 @@ lint:
nf_core_version: 3.5.2
repository_type: pipeline
template:
author: Jonas Demeulemeester
author: Robert Forsyth & Luuk Harbers
description: Workflow for somatic variant calling of long read data
force: false
is_nfcore: false
Expand All @@ -39,4 +39,4 @@ template:
outdir: .
skip_features:
- fastqc
version: 1.1.0dev
version: 1.1.0
42 changes: 25 additions & 17 deletions CHANGELOG.md
Original file line number Diff line number Diff line change
Expand Up @@ -3,32 +3,40 @@
The format is based on [Keep a Changelog](https://keepachangelog.com/en/1.0.0/)
and this project adheres to [Semantic Versioning](https://semver.org/spec/v2.0.0.html).

## v1.1.0dev - [2026-04-10]
## v1.1.0 - [2026-04-28]

### `Added`

- [#152](https://github.com/IntGenomicsLab/lrsomatic/pull/152) - Integrated modkit module for long-read base modification detection and analysis.
- [#149](https://github.com/IntGenomicsLab/lrsomatic/pull/149) - Added DeepVariant and DeepSomatic modules for germline and somatic variant calling from long-read sequencing data.
- [#147](https://github.com/IntGenomicsLab/lrsomatic/pull/147) - Implemented whatshap_stats module to generate phase block statistics and phasing quality metrics.
- [#141](https://github.com/IntGenomicsLab/lrsomatic/pull/141) - Added output of phased variants in separate VCF files for improved downstream analysis.
- [#143](https://github.com/IntGenomicsLab/lrsomatic/pull/143) - Added Severus min_support parameter.
- [#145](https://github.com/IntGenomicsLab/lrsomatic/pull/145) - Integrated MultiQC and nanoplot for comprehensive QC reporting with long-read sequencing metrics.
- [#149](https://github.com/IntGenomicsLab/lrsomatic/pull/149) - Added GPU support for Clair3, DeepVariant, and fibertools
- [#150](https://github.com/IntGenomicsLab/lrsomatic/pull/150) - Added Claude GitHub Actions workflows for automated code review and PR assistance.
- [#117](https://github.com/IntGenomicsLab/lrsomatic/pull/117) - Added ASCAT PDF plots to output (@robert-a-forsyth).
- [#126](https://github.com/IntGenomicsLab/lrsomatic/pull/126) - Added ASCAT raw segments txt files to output (@AmberVerhasselt).
- [#135](https://github.com/IntGenomicsLab/lrsomatic/pull/135) - Added `skip_m6a` parameter to allow skipping m6A base modification steps (@robert-a-forsyth).
- [#141](https://github.com/IntGenomicsLab/lrsomatic/pull/141) - Added output of phased variants in separate VCF files for improved downstream analysis (@ljwharbers).
- [#143](https://github.com/IntGenomicsLab/lrsomatic/pull/143) - Added Severus `min_support` parameter and `skip_fibernormal` option (@ljwharbers).
- [#145](https://github.com/IntGenomicsLab/lrsomatic/pull/145) - Integrated MultiQC and nanoplot for comprehensive QC reporting with long-read sequencing metrics (@ljwharbers).
- [#147](https://github.com/IntGenomicsLab/lrsomatic/pull/147) - Implemented whatshap_stats module to generate phase block statistics and phasing quality metrics (@ljwharbers).
- [#149](https://github.com/IntGenomicsLab/lrsomatic/pull/149) - Added DeepVariant and DeepSomatic modules for germline and somatic variant calling from long-read sequencing data (@robert-a-forsyth).
- [#149](https://github.com/IntGenomicsLab/lrsomatic/pull/149) - Added GPU support for Clair3, DeepVariant, and fibertools (@robert-a-forsyth).
- [#150](https://github.com/IntGenomicsLab/lrsomatic/pull/150) - Added Claude GitHub Actions workflows for automated code review and PR assistance (@ljwharbers).
- [#152](https://github.com/IntGenomicsLab/lrsomatic/pull/152) - Integrated modkit module for long-read base modification detection and analysis (@robert-a-forsyth).

### `Changed`

- [#137](https://github.com/IntGenomicsLab/lrsomatic/pull/137) - Bulk module versions update. Fixed some issues with Wakhan.
- [#138](https://github.com/IntGenomicsLab/lrsomatic/pull/138) - Perform QC before merging replicates
- [#152](https://github.com/IntGenomicsLab/lrsomatic/pull/152) - Updated container versions and dependencies for modkit and related tools.
- [#149](https://github.com/IntGenomicsLab/lrsomatic/pull/149) - Refactored variant calling workflow to support both DeepVariant and existing callers with improved configuration handling.
- [#140](https://github.com/IntGenomicsLab/lrsomatic/pull/140) - Improved documentation with additional pipeline usage examples and configuration guidance.
- [#123](https://github.com/IntGenomicsLab/lrsomatic/pull/123) - Updated channel structure (@robert-a-forsyth).
- [#137](https://github.com/IntGenomicsLab/lrsomatic/pull/137) - Bulk module versions update. Fixed some issues with Wakhan (@ljwharbers).
- [#138](https://github.com/IntGenomicsLab/lrsomatic/pull/138) - Perform QC before merging replicates (@robert-a-forsyth).
- [#140](https://github.com/IntGenomicsLab/lrsomatic/pull/140) - Improved documentation with additional pipeline usage examples and configuration guidance (@ljwharbers).
- [#149](https://github.com/IntGenomicsLab/lrsomatic/pull/149) - Refactored variant calling workflow to support both DeepVariant and existing callers with improved configuration handling (@robert-a-forsyth).
- [#152](https://github.com/IntGenomicsLab/lrsomatic/pull/152) - Updated container versions and dependencies for modkit and related tools (@robert-a-forsyth).
- [#157](https://github.com/IntGenomicsLab/lrsomatic/pull/157) - Added ASAP Panel of Normals citation to CITATIONS.md (@ljwharbers).
- [#160](https://github.com/IntGenomicsLab/lrsomatic/pull/160) - DeepVariant/DeepSomatic optimization and Panel-of-Normals handling improvements; updated docs; removed Claude workflow files (@robert-a-forsyth).

### `Fixed`

- [#137](https://github.com/IntGenomicsLab/lrsomatic/pull/137) - Resolved Nextflow strict syntax compliance issues for compatibility with latest Nextflow versions.
- [#118](https://github.com/IntGenomicsLab/lrsomatic/pull/118) - Updated nf-core template components to align with latest pipeline standards.
- [#149](https://github.com/IntGenomicsLab/lrsomatic/pull/149) - Corrected bcftools and vcfsplit operations for accurate variant filtering and merging.
- [#116](https://github.com/IntGenomicsLab/lrsomatic/pull/116) - Corrected ASCAT GC and RT bias correction (@AmberVerhasselt).
- [#118](https://github.com/IntGenomicsLab/lrsomatic/pull/118) - Updated nf-core template components to align with latest pipeline standards (@ljwharbers).
- [#130](https://github.com/IntGenomicsLab/lrsomatic/pull/130) - Fixed path pattern for rephased VCF files (@Tim-Yu).
- [#137](https://github.com/IntGenomicsLab/lrsomatic/pull/137) - Resolved Nextflow strict syntax compliance issues for compatibility with latest Nextflow versions (@ljwharbers).
- [#149](https://github.com/IntGenomicsLab/lrsomatic/pull/149) - Corrected bcftools and vcfsplit operations for accurate variant filtering and merging (@robert-a-forsyth).

## v1.0.0 - [28 Nov 2025]

Expand Down
4 changes: 2 additions & 2 deletions modules/local/wakhan/main.nf
Original file line number Diff line number Diff line change
Expand Up @@ -4,8 +4,8 @@ process WAKHAN {

conda "${moduleDir}/environment.yml"
container "${ workflow.containerEngine == 'singularity' && !task.ext.singularity_pull_docker_container ?
'docker://robertaforsyth/wakhan:0.4.2_iss58':
'robertaforsyth/wakhan:0.4.2_iss58' }"
'robertaforsyth/wakhan:0.4.2_iss58':
'docker://robertaforsyth/wakhan:0.4.2_iss58' }"

input:
tuple val(meta), path(tumor_input), path(tumor_index), path(normal_input), path(normal_index), path(vcf), path(breakpoints)
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2 changes: 1 addition & 1 deletion nextflow.config
Original file line number Diff line number Diff line change
Expand Up @@ -381,7 +381,7 @@ manifest {
mainScript = 'main.nf'
defaultBranch = 'main'
nextflowVersion = '!>=25.04.0'
version = '1.1.0dev'
version = '1.1.0'
doi = ''
}

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