Request: MS2 noise filtering for TOF data to improve library matching

[chengxiyj-debug]

Would it be possible to implement an MS2 noise filtering method in MS-DIAL specifically for TOF data? For example, during centroiding, if a certain m/z fragment has no adjacent peaks (within 0.001 Da), it could be considered electronic noise. Such electronic noise frequently occurs in AB Sciex data. When analyzing low-abundance DDA results, applying an absolute intensity threshold may remove real MS2 fragment information together with noise; however, without any noise filtering, spectral library matching results suffer.