diff --git a/code/datums/diseases/viruses/_virus.dm b/code/datums/diseases/viruses/_virus.dm
index 6cee6d43282f..493cc252c5ef 100644
--- a/code/datums/diseases/viruses/_virus.dm
+++ b/code/datums/diseases/viruses/_virus.dm
@@ -9,6 +9,7 @@
 	var/infectivity = 65
 	///affects how well the virus will pass through the protection. The more the better. In range (0-2]
 	var/permeability_mod = 1
+	var/no_vaccine = FALSE
 
 /datum/disease/virus/New()
 	..()
diff --git a/code/datums/diseases/viruses/loyalty_syndrome.dm b/code/datums/diseases/viruses/loyalty_syndrome.dm
index 42b1c6cce3c5..584943a91024 100644
--- a/code/datums/diseases/viruses/loyalty_syndrome.dm
+++ b/code/datums/diseases/viruses/loyalty_syndrome.dm
@@ -6,11 +6,11 @@
 	desc = "Болезнь, вызывающая острую массовую одержимость определённым человеком, а также различные навязчивые идеи."
 	spread_flags = CONTACT
 	permeability_mod = 0.8
-	can_immunity = FALSE
 	cure_text = "Галоперидол"
 	cures = list("haloperidol")
 	visibility_flags = HIDDEN_HUD
 	severity = DISEASE_SEVERITY_BIOHAZARD
+	no_vaccine = TRUE
 	var/is_master = FALSE
 	var/mob/living/carbon/human/master
 	var/timer = 0
@@ -164,4 +164,5 @@
 	need_master_death_message = FALSE
 	affected_mob.adjustBrainLoss(50)
 	addtimer(CALLBACK(affected_mob, TYPE_PROC_REF(/mob/living/carbon/human, emote), "cry"), rand(3, 10) SECONDS)
+
 #undef STAGE_TIME
diff --git a/code/modules/reagents/chemistry/machinery/pandemic.dm b/code/modules/reagents/chemistry/machinery/pandemic.dm
index 3f1a8d64994e..fd59dc6bb5a1 100644
--- a/code/modules/reagents/chemistry/machinery/pandemic.dm
+++ b/code/modules/reagents/chemistry/machinery/pandemic.dm
@@ -101,7 +101,6 @@
 						vaccine_name = disease.name
 
 				if(vaccine_type)
-
 					B.name = "вакцина [capitalize(vaccine_name)]"
 					B.ru_names = list(
 						NOMINATIVE = "вакцина [capitalize(vaccine_name)]",
@@ -359,6 +358,15 @@
 			return ..()
 		beaker = I
 		balloon_alert(user, "ёмкость вставлена")
+		var/datum/reagents/reagents = beaker.reagents
+		for(var/datum/reagent/reagent in reagents.reagent_list)
+			if((reagent.id in GLOB.diseases_carrier_reagents) && reagent.data && reagent.data["resistances"])
+				var/list/original_resistances = reagent.data["resistances"]
+				var/list/resistances = original_resistances.Copy()
+				for(var/path in resistances)
+					var/datum/disease/virus/virus_res = new path
+					if(virus_res.no_vaccine)
+						reagent.data["resistances"] -= path
 		updateUsrDialog()
 		update_icon(UPDATE_ICON_STATE)
 		return ATTACK_CHAIN_BLOCKED_ALL
@@ -381,4 +389,3 @@
 
 /obj/machinery/computer/pandemic/wrench_act(mob/living/user, obj/item/I)
 	return default_unfasten_wrench(user, I)
-