diff --git a/src/silx/io/tiledh5.py b/src/silx/io/tiledh5.py
new file mode 100644
index 0000000000..adb020b259
--- /dev/null
+++ b/src/silx/io/tiledh5.py
@@ -0,0 +1,159 @@
+# /*##########################################################################
+# Copyright (C) 2024 European Synchrotron Radiation Facility
+#
+# Permission is hereby granted, free of charge, to any person obtaining a copy
+# of this software and associated documentation files (the "Software"), to deal
+# in the Software without restriction, including without limitation the rights
+# to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
+# copies of the Software, and to permit persons to whom the Software is
+# furnished to do so, subject to the following conditions:
+#
+# The above copyright notice and this permission notice shall be included in
+# all copies or substantial portions of the Software.
+#
+# THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
+# IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
+# FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE
+# AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
+# LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM,
+# OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN
+# THE SOFTWARE.
+#
+# ############################################################################*/
+"""
+Provides a wrapper to expose `Tiled <https://blueskyproject.io/tiled/>`_
+
+This is a preview feature.
+"""
+from __future__ import annotations
+
+
+from functools import lru_cache
+import logging
+import numpy
+from . import commonh5
+import h5py
+import tiled.client
+from tiled.client.cache import Cache
+
+
+_logger = logging.getLogger(__name__)
+
+
+def _get_children(
+    parent: TiledH5 | TiledGroup,
+    container: tiled.client.container.Container,
+    max_children: int | None = None,
+):
+    """Return first max_children entries of given container as a dict of commonh5 wrappers.
+
+    :param parent: The commonh5 wrapper for which to retrieve children.
+    :param container: The tiled container from which to retrieve the entries.
+    :param max_children: The maximum number of children to retrieve.
+    """
+    items = container.items()
+
+    if max_children is not None and len(items) > max_children:
+        items = items.head(max_children)
+        _logger.warning(
+            f"{container.uri} contains too many entries: Only loading first {max_children}."
+        )
+
+    children = {}
+    for key, client in items:
+        if isinstance(client, tiled.client.container.Container):
+            children[key] = TiledGroup(client, name=key, parent=parent)
+        elif isinstance(client, tiled.client.array.ArrayClient):
+            children[key] = TiledDataset(client, name=key, parent=parent)
+        else:
+            _logger.warning(f"Unsupported child type: {key}: {client}")
+            children[key] = commonh5.Dataset(
+                key,
+                numpy.array("Unsupported", h5py.special_dtype(vlen=str)),
+                parent=parent,
+            )
+    return children
+
+
+class TiledH5(commonh5.File):
+    """tiled client wrapper"""
+
+    MAX_CHILDREN_PER_GROUP: int | None = None
+    """Maximum number of children to instantiate for each group.
+
+    Set to None for allowing an unbound number of children per group.
+    """
+
+    _cache = None
+    """Shared tiled cache with lazy initialization"""
+
+    def __init__(
+        self,
+        name: str,
+        mode: str | None = None,
+        attrs: dict | None = None,
+    ):
+        assert mode in ("r", None)
+        super().__init__(name, mode, attrs)
+        if self._cache is None:
+            TiledH5._cache = Cache()  # Use tiled cache default
+        self.__container = tiled.client.from_uri(name, cache=self._cache)
+        assert isinstance(self.__container, tiled.client.container.Container)
+        _logger.warning("tiled support is a preview feature: This may change or be removed without notice.")
+
+    def close(self):
+        super().close()
+        self.__container = None
+
+    @lru_cache
+    def _get_items(self):
+        return _get_children(self, self.__container, self.MAX_CHILDREN_PER_GROUP)
+
+
+class TiledGroup(commonh5.Group):
+    """tiled Container wrapper"""
+
+    def __init__(
+        self,
+        container: tiled.client.container.Container,
+        name: str,
+        parent: TiledH5 | TiledGroup | None = None,
+        attrs: dict | None = None,
+    ):
+        super().__init__(name, parent, attrs)
+        self.__container = container
+
+    @lru_cache
+    def _get_items(self):
+        return _get_children(self, self.__container, self.file.MAX_CHILDREN_PER_GROUP)
+
+
+class TiledDataset(commonh5.Dataset):
+    """tiled ArrayClient wrapper"""
+
+    def __init__(
+        self,
+        client: tiled.client.array.ArrayClient,
+        name: str,
+        parent: TiledH5 | TiledGroup | None = None,
+        attrs: dict | None = None,
+    ):
+        super().__init__(name, client, parent, attrs)
+
+    @property
+    def shape(self):
+        return self._get_data().shape
+
+    @property
+    def size(self):
+        return self._get_data().size
+
+    def __len__(self):
+        return len(self.__client)
+
+    def __getitem__(self, item):
+        return self._get_data()[item]
+
+    @property
+    def value(self):
+        return self._get_data()[()]
diff --git a/src/silx/io/utils.py b/src/silx/io/utils.py
index 352b0c0db1..f655ec0db8 100644
--- a/src/silx/io/utils.py
+++ b/src/silx/io/utils.py
@@ -1,5 +1,5 @@
 # /*##########################################################################
-# Copyright (C) 2016-2023 European Synchrotron Radiation Facility
+# Copyright (C) 2016-2024 European Synchrotron Radiation Facility
 #
 # Permission is hereby granted, free of charge, to any person obtaining a copy
 # of this software and associated documentation files (the "Software"), to deal
@@ -33,13 +33,11 @@
 import time
 import logging
 from typing import Generator, Union, Optional
-import urllib.parse
 
 import numpy
 
 from silx.utils.proxy import Proxy
 from .url import DataUrl
-from . import h5py_utils
 from .._version import calc_hexversion
 
 import h5py
@@ -51,6 +49,12 @@
 except ImportError as e:
     h5pyd = None
 
+try:
+    from .tiledh5 import TiledH5
+except ImportError as e:
+    TiledH5 = None
+
+
 logger = logging.getLogger(__name__)
 
 NEXUS_HDF5_EXT = [".h5", ".nx5", ".nxs", ".hdf", ".hdf5", ".cxi"]
@@ -693,17 +697,30 @@ def open(filename):  # pylint:disable=redefined-builtin
     :rtype: h5py-like node
     """
     url = DataUrl(filename)
+    if url.scheme() in ("http", "https"):
+        errors = [f"Failed to open {filename}"]
+        if h5pyd is not None:
+            try:
+                return _open_url_with_h5pyd(filename)
+            except Exception as e:
+                errors.append(f"- h5pyd failed: {type(e)} {e}")
 
-    if url.scheme() in [None, "file", "silx"]:
-        # That's a local file
-        if not url.is_valid():
-            raise IOError("URL '%s' is not valid" % filename)
-        h5_file = _open_local_file(url.file_path())
-    elif url.scheme() in ("http", "https"):
-        return _open_url_with_h5pyd(filename)
-    else:
+        if TiledH5 is not None:
+            try:
+                return TiledH5(filename)
+            except Exception as e:
+                errors.append(f"- tiled failed: {type(e)} {e}")
+
+        raise IOError("\n".join(errors))
+
+    if url.scheme() not in (None, "file", "silx"):
         raise IOError(f"Unsupported URL scheme {url.scheme}: {filename}")
 
+    # That's a local file
+    if not url.is_valid():
+        raise IOError("URL '%s' is not valid" % filename)
+    h5_file = _open_local_file(url.file_path())
+
     if url.data_path() in [None, "/", ""]:  # The full file is requested
         if url.data_slice():
             raise IOError(f"URL '{filename}' containing slicing is not supported")