diff --git a/reflex/state.py b/reflex/state.py
index b4daa3e69c..d18ab1ef8d 100644
--- a/reflex/state.py
+++ b/reflex/state.py
@@ -2124,6 +2124,8 @@ def __getstate__(self):
         # Never serialize parent_state or substates.
         state["__dict__"].pop("parent_state", None)
         state["__dict__"].pop("substates", None)
+        state["__dict__"].pop("dirty_vars", None)
+        state["__dict__"].pop("dirty_substates", None)
         state["__dict__"].pop("_was_touched", None)
         # Remove all inherited vars.
         for inherited_var_name in self.inherited_vars:
@@ -2140,6 +2142,8 @@ def __setstate__(self, state: dict[str, Any]):
         """
         state["__dict__"]["parent_state"] = None
         state["__dict__"]["substates"] = {}
+        state["__dict__"]["dirty_vars"] = set()
+        state["__dict__"]["dirty_substates"] = set()
         super().__setstate__(state)
 
     def _check_state_size(
diff --git a/tests/units/test_state.py b/tests/units/test_state.py
index 9e952e10f7..a9deec6a5e 100644
--- a/tests/units/test_state.py
+++ b/tests/units/test_state.py
@@ -2532,10 +2532,7 @@ def test_mutable_copy(mutable_state: MutableTestState, copy_func: Callable):
         assert getattr(ms_copy, attr) is not getattr(mutable_state, attr)
     ms_copy.custom.array.append(42)
     assert "custom" in ms_copy.dirty_vars
-    if copy_func is copy.copy:
-        assert "custom" in mutable_state.dirty_vars
-    else:
-        assert not mutable_state.dirty_vars
+    assert not mutable_state.dirty_vars
 
 
 @pytest.mark.parametrize(