diff --git a/DESCRIPTION b/DESCRIPTION
index 837f31b..2aa5534 100644
--- a/DESCRIPTION
+++ b/DESCRIPTION
@@ -22,7 +22,7 @@ LazyData: TRUE
 Roxygen: list(markdown = TRUE)
 RoxygenNote: 7.2.3
 Depends: 
-    Seurat (>= 4.0.1),
+    Seurat (>= 5.0.1),
     ggplot2
 Imports: 
     dplyr,