diff --git a/.env.toolchain b/.env.toolchain
new file mode 100644
index 0000000..0501a9f
--- /dev/null
+++ b/.env.toolchain
@@ -0,0 +1,2 @@
+AMARANTH_USE_YOSYS=builtin
+YOSYS=yowasp-yosys
diff --git a/.gitignore b/.gitignore
index b52ba6d..592200a 100644
--- a/.gitignore
+++ b/.gitignore
@@ -1,8 +1,16 @@
 # Python
 __pycache__/
+__pypackages__/
+dist/
 /*.egg-info
 /.eggs
 
+# pdm
+/.pdm-plugins
+/.pdm-python
+/.venv
+/pdm.lock
+
 # tests
 tests/spec_*/
 *.vcd
diff --git a/README.md b/README.md
index 17a5a66..a4765b3 100644
--- a/README.md
+++ b/README.md
@@ -2,24 +2,15 @@
 
 ## A 32-bit RISC-V soft processor
 
-Minerva is a CPU core that currently implements the [RISC-V][1] RV32IM instruction set. Its microarchitecture is described in plain Python code using the [Amaranth][2] toolbox.
+Minerva is a CPU core that currently implements the [RISC-V][1] RV32IM instruction set. Its microarchitecture is described in plain Python code using [Amaranth HDL][2].
 
 ### Quick start
 
-Minerva requires Python 3.7+ and [Amaranth][2]. Installation instructions for Amaranth can be found [here](https://amaranth-lang.org/docs/amaranth/latest/install.html).
+    pipx install pdm
+    pdm install
+    pdm run python cli.py generate minerva.v
 
-    python setup.py install
-    python cli.py generate > minerva.v
-
-To use Minerva in its minimal configuration, you need to wire the following ports to `minerva_cpu`:
-
-* `clk`
-* `rst`
-* `ibus__*`
-* `dbus__*`
-* `external_interrupt`
-* `timer_interrupt`
-* `software_interrupt`
+See `pdm run python cli.py -h` for more options.
 
 ### Features
 
@@ -53,13 +44,13 @@ The following parameters can be used to configure the Minerva core.
 | `reset_address`   | `0x00000000`   | Reset vector address                               |
 | `with_icache`     | `False`        | Enable the instruction cache                       |
 | `icache_nways`    | `1`            | Number of ways in the instruction cache            |
-| `icache_nlines`   | `128`          | Number of lines in the instruction cache           |
+| `icache_nlines`   | `32`           | Number of lines in the instruction cache           |
 | `icache_nwords`   | `4`            | Number of words in a line of the instruction cache |
 | `icache_base`     | `0x00000000`   | Base of the instruction cache address space        |
 | `icache_limit`    | `0x80000000`   | Limit of the instruction cache address space       |
 | `with_dcache`     | `False`        | Enable the data cache                              |
 | `dcache_nways`    | `1`            | Number of ways in the data cache                   |
-| `dcache_nlines`   | `128`          | Number of lines in the data cache                  |
+| `dcache_nlines`   | `32`           | Number of lines in the data cache                  |
 | `dcache_nwords`   | `4`            | Number of words in a line of the data cache        |
 | `dcache_base`     | `0x00000000`   | Base of the data cache address space               |
 | `dcache_limit`    | `0x80000000`   | Limit of the data cache address space              |
diff --git a/pyproject.toml b/pyproject.toml
new file mode 100644
index 0000000..f76024d
--- /dev/null
+++ b/pyproject.toml
@@ -0,0 +1,32 @@
+[project]
+dynamic = ["version"]
+
+name = "minerva"
+description = "A 32-bit RISC-V soft processor"
+authors = [{name = "Jean-François Nguyen", email = "jf@jfng.fr"}]
+license = {file = "LICENSE.txt"}
+
+requires-python = "~=3.8"
+dependencies = [
+    "amaranth[builtin-yosys]>=0.3,<0.5",
+    "yowasp-yosys",
+]
+
+[project.optional-dependencies]
+debug = ["jtagtap"]
+
+[project.urls]
+"Source Code" = "https://github.com/minerva-cpu/minerva"
+"Bug Tracker" = "https://github.com/minerva-cpu/minerva/issues"
+
+[build-system]
+requires = ["wheel", "setuptools>=67.0", "setuptools_scm[toml]>=6.2"]
+build-backend = "setuptools.build_meta"
+
+[tool.setuptools_scm]
+local_scheme = "node-and-timestamp"
+
+[tool.pdm.scripts]
+_.env_file = ".env.toolchain"
+test.composite = ["test-code"]
+test-code.cmd = "python -m unittest discover -t . -s tests -v"
diff --git a/setup.py b/setup.py
index b866c15..1030e43 100644
--- a/setup.py
+++ b/setup.py
@@ -1,19 +1,3 @@
 from setuptools import setup, find_packages
 
-
-setup(
-    name="minerva",
-    version="0.1",
-    description="A 32-bit RISC-V soft processor",
-    author="Jean-François Nguyen",
-    author_email="jf@jfng.fr",
-    license="BSD",
-    python_requires=">=3.7",
-    install_requires=["amaranth>=0.3,<0.5"],
-    extras_require={ "debug": ["jtagtap"] },
-    packages=find_packages(),
-    project_urls={
-        "Source Code": "https://github.com/minerva-cpu/minerva",
-        "Bug Tracker": "https://github.com/minerva-cpu/minerva/issues"
-    }
-)
+setup()