diff --git a/include/vcpkg/base/contractual-constants.h b/include/vcpkg/base/contractual-constants.h
index 15c712f7fc..abbe26abfc 100644
--- a/include/vcpkg/base/contractual-constants.h
+++ b/include/vcpkg/base/contractual-constants.h
@@ -448,6 +448,7 @@ namespace vcpkg
     inline constexpr StringLiteral CMakeVariableXBoxConsoleTarget = "VCPKG_XBOX_CONSOLE_TARGET";
     inline constexpr StringLiteral CMakeVariableZChainloadToolchainFile = "Z_VCPKG_CHAINLOAD_TOOLCHAIN_FILE";
     inline constexpr StringLiteral CMakeVariableZVcpkgGameDKLatest = "Z_VCPKG_GameDKLatest";
+    inline constexpr StringLiteral CMakeVariableZVcpkgGameDKXboxLatest = "Z_VCPKG_GameDKXboxLatest";
     inline constexpr StringLiteral CMakeVariableZPostPortfileIncludes = "Z_VCPKG_POST_PORTFILE_INCLUDES";
 
     // Policies are PascalCase
diff --git a/include/vcpkg/commands.build.h b/include/vcpkg/commands.build.h
index 13df235c78..528137e4ab 100644
--- a/include/vcpkg/commands.build.h
+++ b/include/vcpkg/commands.build.h
@@ -170,6 +170,7 @@ namespace vcpkg
         std::vector<Path> hash_additional_files;
         std::vector<Path> post_portfile_includes;
         Optional<Path> gamedk_latest_path;
+        Optional<Path> gamedk_xbox_latest_path;
 
         Path toolchain_file() const;
         bool using_vcvars() const;
diff --git a/src/vcpkg/base/system.process.cpp b/src/vcpkg/base/system.process.cpp
index 98c9e4e455..a248372ef3 100644
--- a/src/vcpkg/base/system.process.cpp
+++ b/src/vcpkg/base/system.process.cpp
@@ -635,6 +635,8 @@ namespace vcpkg
             "GameDKLatest",
             "GRDKLatest",
             "GXDKLatest",
+            "GameDKCoreLatest",
+            "GameDKXboxLatest",
         };
 
         std::vector<std::string> env_prefix_string = {
diff --git a/src/vcpkg/cmakevars.cpp b/src/vcpkg/cmakevars.cpp
index 51360c7a33..22c1d02cf0 100644
--- a/src/vcpkg/cmakevars.cpp
+++ b/src/vcpkg/cmakevars.cpp
@@ -174,6 +174,7 @@ VCPKG_HASH_ADDITIONAL_FILES=${VCPKG_HASH_ADDITIONAL_FILES}
 VCPKG_POST_PORTFILE_INCLUDES=${VCPKG_POST_PORTFILE_INCLUDES}
 VCPKG_XBOX_CONSOLE_TARGET=${VCPKG_XBOX_CONSOLE_TARGET}
 Z_VCPKG_GameDKLatest=$ENV{GameDKLatest}
+Z_VCPKG_GameDKXboxLatest=$ENV{GameDKXboxLatest}
 e1e74b5c-18cb-4474-a6bd-5c1c8bc81f3f
 8c504940-be29-4cba-9f8f-6cd83e9d87b7")
 endfunction()
diff --git a/src/vcpkg/commands.build.cpp b/src/vcpkg/commands.build.cpp
index 25fa62e104..c6ce81fcfd 100644
--- a/src/vcpkg/commands.build.cpp
+++ b/src/vcpkg/commands.build.cpp
@@ -1279,24 +1279,42 @@ namespace vcpkg
         return result;
     }
 
+    static Optional<Path> get_grdk_header_path(const PreBuildInfo& pre_build_info)
+    {
+        // Handles new layouts for October 2025 or later.
+        if (auto game_dk_xbox_latest = pre_build_info.gamedk_xbox_latest_path.get())
+        {
+            return *game_dk_xbox_latest / "xbox/include/gxdk.h";
+        }
+
+        // Handles old layouts for April 2025 or earlier for backwards compatibility.
+        if (auto game_dk_latest = pre_build_info.gamedk_latest_path.get())
+        {
+            return *game_dk_latest / "GRDK/gameKit/Include/grdk.h";
+        }
+
+        return nullopt;
+    }
+
     static std::string grdk_hash(const Filesystem& fs,
                                  Cache<Path, Optional<std::string>>& grdk_cache,
                                  const PreBuildInfo& pre_build_info)
     {
-        if (auto game_dk_latest = pre_build_info.gamedk_latest_path.get())
+        auto maybe_gxdk_header_path = get_grdk_header_path(pre_build_info);
+        if (auto gxdk_header_path = maybe_gxdk_header_path.get())
         {
-            const auto grdk_header_path = *game_dk_latest / "GRDK/gameKit/Include/grdk.h";
-            const auto& maybe_header_hash = grdk_cache.get_lazy(grdk_header_path, [&]() -> Optional<std::string> {
-                auto maybe_hash = Hash::get_file_hash(fs, grdk_header_path, Hash::Algorithm::Sha256);
-                if (auto hash = maybe_hash.get())
-                {
-                    return std::move(*hash);
-                }
-                else
-                {
-                    return nullopt;
-                }
-            });
+            const auto& maybe_header_hash =
+                grdk_cache.get_lazy(*gxdk_header_path, [&fs, gxdk_header_path]() -> Optional<std::string> {
+                    auto maybe_hash = Hash::get_file_hash(fs, *gxdk_header_path, Hash::Algorithm::Sha256);
+                    if (auto hash = maybe_hash.get())
+                    {
+                        return std::move(*hash);
+                    }
+                    else
+                    {
+                        return nullopt;
+                    }
+                });
 
             if (auto header_hash = maybe_header_hash.get())
             {
@@ -2231,6 +2249,7 @@ namespace vcpkg
         }
 
         Util::assign_if_set_and_nonempty(gamedk_latest_path, cmakevars, CMakeVariableZVcpkgGameDKLatest);
+        Util::assign_if_set_and_nonempty(gamedk_xbox_latest_path, cmakevars, CMakeVariableZVcpkgGameDKXboxLatest);
     }
 
     ExtendedBuildResult::ExtendedBuildResult(BuildResult code) : code(code) { }