diff --git a/build.py b/build.py
index 0922a84b0ee..c85f80ac67d 100755
--- a/build.py
+++ b/build.py
@@ -70,7 +70,11 @@ def find_java():
 
 
 def calculate_memory_args():
-    return "-Xmx600M -XX:MaxPermSize=256m".split(" ")
+    return (
+        "-Xmx600M",
+        "-XX:MaxPermSize=256m",
+        "-XX:+IgnoreUnrecognizedVMOptions"
+    )
 
 
 def handle_tools(args):
diff --git a/components/antlib/resources/lifecycle.xml b/components/antlib/resources/lifecycle.xml
index 37df801d722..2300e1dc191 100644
--- a/components/antlib/resources/lifecycle.xml
+++ b/components/antlib/resources/lifecycle.xml
@@ -202,6 +202,7 @@ omero.version=${omero.version}
                     <pathelement location="${test.dir}"/>
                 </classpath>
                 <jvmarg value="-XX:MaxPermSize=256m"/>
+                <jvmarg value="-XX:+IgnoreUnrecognizedVMOptions"/>
                 <jvmarg value="-Dlogback.configuration=logback-build.xml"/>
                 <jvmarg value="-Domero.db.name=${omero.db.name}"/>
                 <jvmarg value="-Domero.db.host=${omero.db.host}"/>
diff --git a/components/tools/OmeroPy/src/omero/install/jvmcfg.py b/components/tools/OmeroPy/src/omero/install/jvmcfg.py
index 2374eea3071..59cbec17d41 100755
--- a/components/tools/OmeroPy/src/omero/install/jvmcfg.py
+++ b/components/tools/OmeroPy/src/omero/install/jvmcfg.py
@@ -279,6 +279,8 @@ def get_memory_settings(self):
             self.get_heap_dump(),
             self.get_perm_gen(),
         ]
+        if any([x.startswith("-XX:MaxPermSize") for x in values]):
+            values.append("-XX:+IgnoreUnrecognizedVMOptions")
         values += self.get_append()
         return [x for x in values if x]
 
diff --git a/components/tools/OmeroPy/test/unit/old_templates.xml b/components/tools/OmeroPy/test/unit/old_templates.xml
index cb1391797be..ce49a6b3ed0 100644
--- a/components/tools/OmeroPy/test/unit/old_templates.xml
+++ b/components/tools/OmeroPy/test/unit/old_templates.xml
@@ -199,6 +199,7 @@
              See #4670
         -->
         <option>-XX:MaxPermSize=128m</option>
+        <option>-XX:+IgnoreUnrecognizedVMOptions</option>
         <target name="memcfg">
             <option>${omero.blitz.maxmemory}</option>
             <option>${omero.blitz.permgen}</option>
diff --git a/components/tools/OmeroPy/test/unit/test_jvmcfg.json b/components/tools/OmeroPy/test/unit/test_jvmcfg.json
index 9f322d2f82d..d55f30714d5 100644
--- a/components/tools/OmeroPy/test/unit/test_jvmcfg.json
+++ b/components/tools/OmeroPy/test/unit/test_jvmcfg.json
@@ -9,6 +9,7 @@
             "blitz" : [
                 "-Xmx512m",
                 "-XX:MaxPermSize=128m",
+                "-XX:+IgnoreUnrecognizedVMOptions",
                 "foo",
                 "bar"
             ]
@@ -22,7 +23,8 @@
         "output": {
             "blitz" : [
                 "-Xmx512m",
-                "-XX:MaxPermSize=128m"
+                "-XX:MaxPermSize=128m",
+                "-XX:+IgnoreUnrecognizedVMOptions"
             ]
         }
     },
@@ -35,7 +37,8 @@
         "output": {
             "blitz" : [
                 "-Xmx1G",
-                "-XX:MaxPermSize=128m"
+                "-XX:MaxPermSize=128m",
+                "-XX:+IgnoreUnrecognizedVMOptions"
             ]
         }
     },
@@ -49,7 +52,8 @@
             "blitz" : [
                 "-Xmx512m",
                 "-XX:+HeapDumpOnOutOfMemoryError",
-                "-XX:MaxPermSize=128m"
+                "-XX:MaxPermSize=128m",
+                "-XX:+IgnoreUnrecognizedVMOptions"
             ]
         }
     },
@@ -62,7 +66,8 @@
         "output": {
             "blitz" : [
                 "-Xmx512m",
-                "-XX:MaxPermSize=1G"
+                "-XX:MaxPermSize=1G",
+                "-XX:+IgnoreUnrecognizedVMOptions"
             ]
         }
     },
@@ -75,7 +80,8 @@
         "output": {
             "blitz" : [
                 "-Xmx512m",
-                "-XX:MaxPermSize=256m"
+                "-XX:MaxPermSize=256m",
+                "-XX:+IgnoreUnrecognizedVMOptions"
             ]
         }
     },
@@ -89,7 +95,8 @@
         "output": {
             "blitz" : [
                 "-Xmx150m",
-                "-XX:MaxPermSize=128m"
+                "-XX:MaxPermSize=128m",
+                "-XX:+IgnoreUnrecognizedVMOptions"
             ]
         }
     },
@@ -102,7 +109,8 @@
         "output": {
             "blitz" : [
                 "-Xmx600m",
-                "-XX:MaxPermSize=256m"
+                "-XX:MaxPermSize=256m",
+                "-XX:+IgnoreUnrecognizedVMOptions"
             ]
         }
     },
@@ -115,7 +123,8 @@
         "output": {
             "blitz" : [
                 "-Xmx1200m",
-                "-XX:MaxPermSize=512m"
+                "-XX:MaxPermSize=512m",
+                "-XX:+IgnoreUnrecognizedVMOptions"
             ]
         }
     },
@@ -128,7 +137,8 @@
         "output": {
             "blitz" : [
                 "-Xmx3600m",
-                "-XX:MaxPermSize=1g"
+                "-XX:MaxPermSize=1g",
+                "-XX:+IgnoreUnrecognizedVMOptions"
             ]
         }
     },
@@ -141,7 +151,8 @@
         "output": {
             "blitz" : [
                 "-Xmx7200m",
-                "-XX:MaxPermSize=1g"
+                "-XX:MaxPermSize=1g",
+                "-XX:+IgnoreUnrecognizedVMOptions"
             ]
         }
     },
@@ -154,7 +165,8 @@
         "output": {
             "blitz" : [
                 "-Xmx7200m",
-                "-XX:MaxPermSize=1g"
+                "-XX:MaxPermSize=1g",
+                "-XX:+IgnoreUnrecognizedVMOptions"
             ]
         }
     },
@@ -168,7 +180,8 @@
         "output": {
             "blitz" : [
                 "-Xmx9600m",
-                "-XX:MaxPermSize=1g"
+                "-XX:MaxPermSize=1g",
+                "-XX:+IgnoreUnrecognizedVMOptions"
             ]
         }
     },
@@ -182,6 +195,7 @@
             "blitz" : [
                 "-Xmx512m",
                 "-XX:MaxPermSize=128m",
+                "-XX:+IgnoreUnrecognizedVMOptions",
                 "foo"
             ]
         }
@@ -196,7 +210,8 @@
         "output": {
             "blitz" : [
                 "-Xmx4000m",
-                "-XX:MaxPermSize=512m"
+                "-XX:MaxPermSize=512m",
+                "-XX:+IgnoreUnrecognizedVMOptions"
             ]
         }
     },
@@ -209,15 +224,18 @@
         "output": {
             "blitz" : [
                 "-Xmx1200m",
-                "-XX:MaxPermSize=512m"
+                "-XX:MaxPermSize=512m",
+                "-XX:+IgnoreUnrecognizedVMOptions"
             ],
             "pixeldata" : [
                 "-Xmx1200m",
-                "-XX:MaxPermSize=512m"
+                "-XX:MaxPermSize=512m",
+                "-XX:+IgnoreUnrecognizedVMOptions"
             ],
             "indexer" : [
                 "-Xmx800m",
-                "-XX:MaxPermSize=512m"
+                "-XX:MaxPermSize=512m",
+                "-XX:+IgnoreUnrecognizedVMOptions"
             ]
         }
     },
@@ -230,7 +248,8 @@
         "output": {
             "blitz" : [
                 "-Xmx4g",
-                "-XX:MaxPermSize=256m"
+                "-XX:MaxPermSize=256m",
+                "-XX:+IgnoreUnrecognizedVMOptions"
             ]
         }
     }
diff --git a/components/tools/OmeroPy/test/unit/test_jvmcfg.py b/components/tools/OmeroPy/test/unit/test_jvmcfg.py
index 5e60eb81f29..277f9ca79bb 100644
--- a/components/tools/OmeroPy/test/unit/test_jvmcfg.py
+++ b/components/tools/OmeroPy/test/unit/test_jvmcfg.py
@@ -153,6 +153,7 @@ def test_hard_coded(self):
         assert settings == [
             "-Xmx512m",
             "-XX:MaxPermSize=128m",
+            "-XX:+IgnoreUnrecognizedVMOptions",
         ]
 
     def test_percent_usage(self):