diff --git a/src/tests/tribol_enzyme_poly_intersect.cpp b/src/tests/tribol_enzyme_poly_intersect.cpp
index 63702e0f..ce28e15b 100644
--- a/src/tests/tribol_enzyme_poly_intersect.cpp
+++ b/src/tests/tribol_enzyme_poly_intersect.cpp
@@ -21,7 +21,6 @@
 
 #include "mfem.hpp"
 
-#include "tribol/common/Enzyme.hpp"
 #include "tribol/geom/GeomUtilities.hpp"
 
 namespace tribol {
diff --git a/src/tribol/CMakeLists.txt b/src/tribol/CMakeLists.txt
index 99e1689f..2d26f6f6 100644
--- a/src/tribol/CMakeLists.txt
+++ b/src/tribol/CMakeLists.txt
@@ -14,7 +14,6 @@ set(tribol_headers
     common/ArrayTypes.hpp
     common/BasicTypes.hpp
     common/Containers.hpp
-    common/Enzyme.hpp
     common/ExecModel.hpp
     common/LoopExec.hpp
     common/Parameters.hpp
diff --git a/src/tribol/common/Enzyme.hpp b/src/tribol/common/Enzyme.hpp
deleted file mode 100644
index 42bf8ca5..00000000
--- a/src/tribol/common/Enzyme.hpp
+++ /dev/null
@@ -1,40 +0,0 @@
-// Copyright (c) 2017-2025, Lawrence Livermore National Security, LLC and
-// other Tribol Project Developers. See the top-level LICENSE file for details.
-//
-// SPDX-License-Identifier: (MIT)
-
-#ifndef TRIBOL_COMMON_ENZYME_HPP_
-#define TRIBOL_COMMON_ENZYME_HPP_
-
-// Tribol includes
-#include "tribol/config.hpp"
-
-#ifdef TRIBOL_USE_ENZYME
-/*
- * Enzyme is an LLVM-based automatic differentiation (AD) tool that enables
- * efficient computation of derivatives directly from code at compile time.
- *
- * Variables prefixed with enzyme_* or function types prefixed with __enzyme_*,
- * are variables which will get preprocessed in the LLVM intermediate
- * representation when the Enzyme LLVM plugin is loaded.
- *
- * For more details, see the Enzyme documentation: https://enzyme.mit.edu
- */
-
-extern int enzyme_dup;
-extern int enzyme_dupnoneed;
-extern int enzyme_out;
-extern int enzyme_const;
-
-extern int enzyme_runtime_activity;
-
-// Reverse mode autodiff
-template <typename return_type, typename... Args>
-return_type __enzyme_autodiff( Args... );
-
-// Forward mode autodiff
-template <typename return_type, typename... Args>
-return_type __enzyme_fwddiff( Args... );
-#endif
-
-#endif /* TRIBOL_COMMON_ENZYME_HPP_ */
diff --git a/src/tribol/geom/GeomUtilities.cpp b/src/tribol/geom/GeomUtilities.cpp
index a6d1ee2a..5a80add9 100644
--- a/src/tribol/geom/GeomUtilities.cpp
+++ b/src/tribol/geom/GeomUtilities.cpp
@@ -9,7 +9,7 @@
 #include "tribol/utils/Math.hpp"
 
 #ifdef TRIBOL_USE_ENZYME
-#include "tribol/common/Enzyme.hpp"
+#include "mfem/general/enzyme.hpp"
 #endif
 
 #include "axom/core.hpp"
diff --git a/src/tribol/geom/NodalNormal.cpp b/src/tribol/geom/NodalNormal.cpp
index cba66038..ded86d88 100644
--- a/src/tribol/geom/NodalNormal.cpp
+++ b/src/tribol/geom/NodalNormal.cpp
@@ -9,7 +9,7 @@
 #include "tribol/utils/Math.hpp"
 
 #ifdef TRIBOL_USE_ENZYME
-#include "tribol/common/Enzyme.hpp"
+#include "mfem/general/enzyme.hpp"
 #endif
 
 namespace tribol {
diff --git a/src/tribol/physics/Mortar.cpp b/src/tribol/physics/Mortar.cpp
index ca88f617..94433da7 100644
--- a/src/tribol/physics/Mortar.cpp
+++ b/src/tribol/physics/Mortar.cpp
@@ -25,7 +25,7 @@
 #include <iomanip>
 
 #ifdef TRIBOL_USE_ENZYME
-#include "tribol/common/Enzyme.hpp"
+#include "mfem/general/enzyme.hpp"
 #endif
 
 namespace tribol {