Create modules of co-signaling cytokines for analysis of multiplexed cytokine data (e.g. Luminex).
Example notebook: https://nbviewer.jupyter.org/github/liel-cohen/CytoMod/blob/master/cytomod_notebook.ipynb
Method presented in paper:
"A Modular Cytokine Analysis Method Reveals Novel Associations With Clinical Phenotypes and Identifies Sets of Co-signaling Cytokines Across Influenza Natural Infection Cohorts and Healthy Controls"
By Cohen Liel, Fiore-Gartland Andrew, Randolph Adrienne G., Panoskaltsis-Mortari Angela, Wong Sook-San, Ralston Jacqui, Wood Timothy, Seeds Ruth, Huang Q. Sue, Webby Richard J., Thomas Paul G. and Hertz Tomer
https://www.frontiersin.org/articles/10.3389/fimmu.2019.01338/full