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Update docs/source/how_cat-vrs-works.rst
Kori MVP Co-authored-by: Kori Kuzma <[email protected]>
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docs/source/how_cat-vrs-works.rst

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@@ -26,7 +26,7 @@ The figure below shows how variant matching via Cat-VRS effectuates knowledge in
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.. image:: images/Cat-VRS use_function figures - Figure 1.png
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:width: 80%
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:alt: The figure depicts an assayed variant from a patient,and two separate knowledgebase entries, each with associated genomic knowledge. Due to differing representation formats, these variants and assocaited knowledge are all siloed. However, by representing them with Cat-VRS, each are converted into categorical variant representations under a single common representation specification. As a result, the Cat-VRS representations become easily comparable with each other, and both assayed-to-categorical and categorical-to-categorical variant matching becomes possible under a common framework. By extension, the knowledge of each respective knowledgebase entry can be integrated as part of knowledgebase curation, or applied to the assayed variant of interest in clinical pipelines.
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:alt: The figure depicts an assayed variant from a patient, and two separate knowledgebase entries, each with associated genomic knowledge. Due to differing representation formats, these variants and associated knowledge are all siloed. However, by representing them with Cat-VRS, each are converted into categorical variant representations under a single common representation specification. As a result, the Cat-VRS representations become easily comparable with each other, and both assayed-to-categorical and categorical-to-categorical variant matching becomes possible under a common framework. By extension, the knowledge of each respective knowledgebase entry can be integrated as part of knowledgebase curation, or applied to the assayed variant of interest in clinical pipelines.
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.. Matching by Constraints
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