diff --git a/sqlmodel/sql/sqltypes.py b/sqlmodel/sql/sqltypes.py
index 512daacbab..1bd18023cc 100644
--- a/sqlmodel/sql/sqltypes.py
+++ b/sqlmodel/sql/sqltypes.py
@@ -1,16 +1,106 @@
-from typing import Any, cast
+from typing import (
+    Any,
+    Dict,
+    List,
+    Optional,
+    Type,
+    TypeVar,
+    Union,
+    cast,
+    get_args,
+    get_origin,
+)
 
+from pydantic import BaseModel
+from pydantic_core import to_jsonable_python
 from sqlalchemy import types
+from sqlalchemy.dialects.postgresql import JSONB  # for Postgres JSONB
 from sqlalchemy.engine.interfaces import Dialect
 
+BaseModelType = TypeVar("BaseModelType", bound=BaseModel)
+
+# Define a type alias for JSON-serializable values
+JSONValue = Union[Dict[str, Any], List[Any], str, int, float, bool, None]
+
 
 class AutoString(types.TypeDecorator):  # type: ignore
     impl = types.String
     cache_ok = True
     mysql_default_length = 255
 
-    def load_dialect_impl(self, dialect: Dialect) -> "types.TypeEngine[Any]":
+    def load_dialect_impl(self, dialect: Dialect) -> types.TypeEngine[Any]:
         impl = cast(types.String, self.impl)
         if impl.length is None and dialect.name == "mysql":
             return dialect.type_descriptor(types.String(self.mysql_default_length))
         return super().load_dialect_impl(dialect)
+
+
+class PydanticJSONB(types.TypeDecorator):  # type: ignore
+    """Custom type to automatically handle Pydantic model serialization."""
+
+    impl = JSONB  # use JSONB type in Postgres (fallback to JSON for others)
+    cache_ok = True  # allow SQLAlchemy to cache results
+
+    def __init__(
+        self,
+        model_class: Union[
+            Type[BaseModelType],
+            Type[List[BaseModelType]],
+            Type[Dict[str, BaseModelType]],
+        ],
+        *args: Any,
+        **kwargs: Any,
+    ):
+        super().__init__(*args, **kwargs)
+        self.model_class = model_class  # Pydantic model class to use
+
+    def process_bind_param(self, value: Any, dialect: Any) -> JSONValue:  # noqa: ANN401, ARG002, ANN001
+        if value is None:
+            return None
+        if isinstance(value, BaseModel):
+            return value.model_dump(mode="json")
+        if isinstance(value, list):
+            return [
+                m.model_dump(mode="json")
+                if isinstance(m, BaseModel)
+                else to_jsonable_python(m)
+                for m in value
+            ]
+        if isinstance(value, dict):
+            return {
+                k: v.model_dump(mode="json")
+                if isinstance(v, BaseModel)
+                else to_jsonable_python(v)
+                for k, v in value.items()
+            }
+
+        # We know to_jsonable_python returns a JSON-serializable value, but mypy sees it as Any
+        return to_jsonable_python(value)  # type: ignore[no-any-return]
+
+    def process_result_value(
+        self, value: Any, dialect: Any
+    ) -> Optional[Union[BaseModelType, List[BaseModelType], Dict[str, BaseModelType]]]:  # noqa: ANN401, ARG002, ANN001
+        if value is None:
+            return None
+        if isinstance(value, dict):
+            # If model_class is a Dict type hint, handle key-value pairs
+            origin = get_origin(self.model_class)
+            if origin is dict:
+                model_class = get_args(self.model_class)[
+                    1
+                ]  # Get the value type (the model)
+                return {k: model_class.model_validate(v) for k, v in value.items()}
+            # Regular case: the whole dict represents a single model
+            return self.model_class.model_validate(value)  # type: ignore
+        if isinstance(value, list):
+            # If model_class is a List type hint
+            origin = get_origin(self.model_class)
+            if origin is list:
+                model_class = get_args(self.model_class)[0]
+                return [model_class.model_validate(v) for v in value]
+            # Fallback case (though this shouldn't happen given our __init__ types)
+            return [self.model_class.model_validate(v) for v in value]  # type: ignore
+
+        raise TypeError(
+            f"Unsupported type for PydanticJSONB from database: {type(value)}. Expected a dictionary or list."
+        )