diff --git a/src/Grpc/Interop/test/InteropTests/InteropTests.cs b/src/Grpc/Interop/test/InteropTests/InteropTests.cs
index da2adfef1cec..21c6aa2fb1cc 100644
--- a/src/Grpc/Interop/test/InteropTests/InteropTests.cs
+++ b/src/Grpc/Interop/test/InteropTests/InteropTests.cs
@@ -22,6 +22,7 @@ public InteropTests(ITestOutputHelper output)
     }
 
     [Fact]
+    [QuarantinedTest("https://github.com/dotnet/aspnetcore/issues/61291")]
     public Task EmptyUnary() => InteropTestCase("empty_unary");
 
     [Fact]