diff --git a/packages/react-native/ReactAndroid/src/main/java/com/facebook/react/ReactPackageTurboModuleManagerDelegate.java b/packages/react-native/ReactAndroid/src/main/java/com/facebook/react/ReactPackageTurboModuleManagerDelegate.java
index 30ef9e019b3783..949276ec20b195 100644
--- a/packages/react-native/ReactAndroid/src/main/java/com/facebook/react/ReactPackageTurboModuleManagerDelegate.java
+++ b/packages/react-native/ReactAndroid/src/main/java/com/facebook/react/ReactPackageTurboModuleManagerDelegate.java
@@ -10,6 +10,7 @@
 import androidx.annotation.Nullable;
 import com.facebook.common.logging.FLog;
 import com.facebook.infer.annotation.Assertions;
+import com.facebook.jni.HybridData;
 import com.facebook.react.bridge.CxxModuleWrapper;
 import com.facebook.react.bridge.ModuleSpec;
 import com.facebook.react.bridge.NativeModule;
@@ -53,13 +54,22 @@ interface ModuleProvider {
   private List<ReactPackage> mPackages;
   private ReactApplicationContext mReactContext;
 
-  protected ReactPackageTurboModuleManagerDelegate() {
+  protected ReactPackageTurboModuleManagerDelegate(
+      ReactApplicationContext reactApplicationContext, List<ReactPackage> packages) {
     super();
+    initialize(reactApplicationContext, packages);
   }
 
   protected ReactPackageTurboModuleManagerDelegate(
+      ReactApplicationContext reactApplicationContext,
+      List<ReactPackage> packages,
+      HybridData hybridData) {
+    super(hybridData);
+    initialize(reactApplicationContext, packages);
+  }
+
+  private void initialize(
       ReactApplicationContext reactApplicationContext, List<ReactPackage> packages) {
-    super();
     if (mIsLazy) {
       mPackages = packages;
       mReactContext = reactApplicationContext;
diff --git a/packages/react-native/ReactAndroid/src/main/java/com/facebook/react/defaults/DefaultTurboModuleManagerDelegate.kt b/packages/react-native/ReactAndroid/src/main/java/com/facebook/react/defaults/DefaultTurboModuleManagerDelegate.kt
index 10a7dc7c5d2f75..ad38bb31f10e61 100644
--- a/packages/react-native/ReactAndroid/src/main/java/com/facebook/react/defaults/DefaultTurboModuleManagerDelegate.kt
+++ b/packages/react-native/ReactAndroid/src/main/java/com/facebook/react/defaults/DefaultTurboModuleManagerDelegate.kt
@@ -28,12 +28,13 @@ private constructor(
     context: ReactApplicationContext,
     packages: List<ReactPackage>,
     private val eagerlyInitializedModules: List<String>,
-    private val cxxReactPackage: CxxReactPackage?,
-) : ReactPackageTurboModuleManagerDelegate(context, packages) {
+    cxxReactPackage: CxxReactPackage?,
+) : ReactPackageTurboModuleManagerDelegate(context, packages, initHybrid(cxxReactPackage)) {
 
-  @DoNotStrip override fun initHybrid() = initHybrid(cxxReactPackage)
-
-  external fun initHybrid(cxxReactPackage: CxxReactPackage?): HybridData?
+  override fun initHybrid(): HybridData? {
+    throw UnsupportedOperationException(
+        "DefaultTurboModuleManagerDelegate.initHybrid() must never be called!")
+  }
 
   override fun getEagerInitModuleNames(): List<String> {
     if (unstable_isLazyTurboModuleDelegate()) {
@@ -62,8 +63,11 @@ private constructor(
         DefaultTurboModuleManagerDelegate(context, packages, eagerInitModuleNames, cxxReactPackage)
   }
 
-  @Synchronized
-  override fun maybeLoadOtherSoLibraries() {
-    DefaultSoLoader.maybeLoadSoLibrary()
+  companion object {
+    init {
+      DefaultSoLoader.maybeLoadSoLibrary()
+    }
+
+    @DoNotStrip @JvmStatic external fun initHybrid(cxxReactPackage: CxxReactPackage?): HybridData?
   }
 }
diff --git a/packages/react-native/ReactAndroid/src/main/java/com/facebook/react/internal/turbomodule/core/TurboModuleManagerDelegate.java b/packages/react-native/ReactAndroid/src/main/java/com/facebook/react/internal/turbomodule/core/TurboModuleManagerDelegate.java
index 2740fa7208ae7d..7cb82679a3aefa 100644
--- a/packages/react-native/ReactAndroid/src/main/java/com/facebook/react/internal/turbomodule/core/TurboModuleManagerDelegate.java
+++ b/packages/react-native/ReactAndroid/src/main/java/com/facebook/react/internal/turbomodule/core/TurboModuleManagerDelegate.java
@@ -31,6 +31,11 @@ protected TurboModuleManagerDelegate() {
     mHybridData = initHybrid();
   }
 
+  protected TurboModuleManagerDelegate(HybridData hybridData) {
+    maybeLoadOtherSoLibraries();
+    mHybridData = hybridData;
+  }
+
   /**
    * Create and return a TurboModule Java object with name `moduleName`. If `moduleName` isn't a
    * TurboModule, return null.
@@ -77,5 +82,7 @@ public boolean unstable_enableSyncVoidMethods() {
     return false;
   }
 
+  // TODO(T171231381): Consider removing this method: could we just use the static initializer
+  // of derived classes instead?
   protected synchronized void maybeLoadOtherSoLibraries() {}
 }
diff --git a/packages/react-native/ReactAndroid/src/main/jni/react/newarchdefaults/DefaultTurboModuleManagerDelegate.cpp b/packages/react-native/ReactAndroid/src/main/jni/react/newarchdefaults/DefaultTurboModuleManagerDelegate.cpp
index 86944f2e6c4a20..fc480af328b6ee 100644
--- a/packages/react-native/ReactAndroid/src/main/jni/react/newarchdefaults/DefaultTurboModuleManagerDelegate.cpp
+++ b/packages/react-native/ReactAndroid/src/main/jni/react/newarchdefaults/DefaultTurboModuleManagerDelegate.cpp
@@ -27,7 +27,7 @@ std::function<std::shared_ptr<TurboModule>(
 
 jni::local_ref<DefaultTurboModuleManagerDelegate::jhybriddata>
 DefaultTurboModuleManagerDelegate::initHybrid(
-    jni::alias_ref<jhybridobject>,
+    jni::alias_ref<jclass> jClass,
     jni::alias_ref<CxxReactPackage::javaobject> cxxReactPackage) {
   return makeCxxInstance(cxxReactPackage);
 }
@@ -43,9 +43,12 @@ std::shared_ptr<TurboModule> DefaultTurboModuleManagerDelegate::getTurboModule(
     const std::string& name,
     const std::shared_ptr<CallInvoker>& jsInvoker) {
   if (cxxReactPackage_) {
-    auto module = cxxReactPackage_->cthis()->getModule(name, jsInvoker);
-    if (module) {
-      return module;
+    auto cppPart = cxxReactPackage_->cthis();
+    if (cppPart) {
+      auto module = cppPart->getModule(name, jsInvoker);
+      if (module) {
+        return module;
+      }
     }
   }
 
diff --git a/packages/react-native/ReactAndroid/src/main/jni/react/newarchdefaults/DefaultTurboModuleManagerDelegate.h b/packages/react-native/ReactAndroid/src/main/jni/react/newarchdefaults/DefaultTurboModuleManagerDelegate.h
index e175a574bc394b..687a23b0c29062 100644
--- a/packages/react-native/ReactAndroid/src/main/jni/react/newarchdefaults/DefaultTurboModuleManagerDelegate.h
+++ b/packages/react-native/ReactAndroid/src/main/jni/react/newarchdefaults/DefaultTurboModuleManagerDelegate.h
@@ -24,7 +24,7 @@ class DefaultTurboModuleManagerDelegate : public jni::HybridClass<
       "Lcom/facebook/react/defaults/DefaultTurboModuleManagerDelegate;";
 
   static jni::local_ref<jhybriddata> initHybrid(
-      jni::alias_ref<jhybridobject>,
+      jni::alias_ref<jclass>,
       jni::alias_ref<CxxReactPackage::javaobject>);
 
   static void registerNatives();
@@ -53,7 +53,7 @@ class DefaultTurboModuleManagerDelegate : public jni::HybridClass<
   jni::global_ref<CxxReactPackage::javaobject> cxxReactPackage_;
 
   DefaultTurboModuleManagerDelegate(
-      jni::alias_ref<CxxReactPackage::javaobject>);
+      jni::alias_ref<CxxReactPackage::javaobject> cxxReactPackage);
 };
 
 } // namespace facebook::react