Curie CLI

Command-line interface for the Curie scientific AI platform. Run biology, chemistry, and physics models directly from your terminal.

Installation

pip install curie-cli

curie auth login

Or set your API key as an environment variable:

export CURIE_API_KEY="sk-..."

Get your API key at curie.sh/dashboard/keys. First 500 calls are free.

curie fold MKTIIALSYIFCLVFA
curie fold MKTIIALSYIFCLVFA --output structure.pdb

curie dock --protein structure.pdb --ligand "CC(=O)Oc1ccccc1C(=O)O"
curie dock --protein structure.pdb --ligand aspirin.sml --output pose.pdb

curie embed MKTIIALSYIFCLVFA
curie embed MKTIIALSYIFCLVFA --output embeddings.json

curie models
curie models --domain biology

Model	Domain	Description	Latency
`esm/esmfold-v1`	Biology	Protein structure prediction	~200ms
`mit/boltz-2`	Biology	Biomolecular complex prediction	~2min
`baker/proteinmpnn`	Biology	Protein sequence design	~300ms
`meta/esm-2-650m`	Biology	Protein language model embeddings	~90ms
`mit/diffdock`	Chemistry	Molecular docking	~800ms

MIT — see LICENSE