diff --git a/.gitignore b/.gitignore
new file mode 100644
index 00000000..53dccac3
--- /dev/null
+++ b/.gitignore
@@ -0,0 +1,4 @@
+.snakemake/
+example_data/output/
+example_data/reference/STARIndex/
+example_data/reference/SalmonIndex/
\ No newline at end of file
diff --git a/Dockerfile b/Dockerfile
new file mode 100644
index 00000000..d54f1452
--- /dev/null
+++ b/Dockerfile
@@ -0,0 +1,9 @@
+FROM continuumio/miniconda3
+
+WORKDIR /app
+
+# Prepare environment
+RUN conda config --add channels bioconda
+RUN conda config --add channels conda-forge
+RUN conda install -y -c conda-forge mamba=0.23.3
+RUN mamba install -y -c bioconda snakemake=6.10.0
diff --git a/README.md b/README.md
index 75e1f677..8269fc00 100755
--- a/README.md
+++ b/README.md
@@ -19,6 +19,11 @@ git clone https://github.com/csoneson/ARMOR.git
 cd ARMOR && snakemake --use-conda
 ```
 
+Or using docker:
+```
+docker-compose up
+```
+
 To use the ARMOR workflow on your own data, follow the steps outlined in the [wiki](https://github.com/csoneson/ARMOR/wiki).
 
 ## Workflow graph
diff --git a/docker-compose.yml b/docker-compose.yml
new file mode 100644
index 00000000..ce515c7e
--- /dev/null
+++ b/docker-compose.yml
@@ -0,0 +1,7 @@
+version: "3.9"
+services:
+  armor:
+    build: .
+    volumes:
+      - ./:/app
+    command: snakemake --use-conda --cores all
\ No newline at end of file