index.md

<title>Ion</title>

Open Probability of Ion Channels

Adam Berridge, Phil Vorce, Irene Galca, Jordan Hiatt

  <div class="abstract">
    <h2>Abstract</h2>
    <p>
      Our sponsor's research consists of collecting data on the amount of current
      across a membrane in response to an increase in voltage. As voltage increases
      the current rises linearly for some time before tapering off due to ion
      channels closing. Our sponsor requested a software tool to analyze these
      data points and the data points of a linear regression representing projected
      values had all ion channels remained opened. He also requested a way to
      visualize the actual current over the projected current if all ion channels
      remained open, commonly referred to as the open probability of the membrane.
    </p>
  </div>


  <div class="description">
    <h2>Project Description</h2>
    <p>
      Our solution was build a graphical user interface using the Python programming
      language. A .csv file can be seleccted from disk. If the data in the file
      is properly formatted two graphs are plotted. The first graph holds the data from the
      .csv, along with an interactive regression line. The second graph charts
      the open probability. The values of the regression and open probability can
      be saved to disk.
    </p>
  </div>


  <img src="openProb.png" style="width:auto; height:500px; display:block; margin-left:auto; margin-right:auto;">
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