diff --git a/CondCore/AlignmentPlugins/test/testTrackerAlignmentPayloadInspector.cpp b/CondCore/AlignmentPlugins/test/testTrackerAlignmentPayloadInspector.cpp
index 486c5d7d2824d..7124f3ff69990 100644
--- a/CondCore/AlignmentPlugins/test/testTrackerAlignmentPayloadInspector.cpp
+++ b/CondCore/AlignmentPlugins/test/testTrackerAlignmentPayloadInspector.cpp
@@ -22,8 +22,8 @@ int main(int argc, char** argv) {
   std::string connectionString("frontier://FrontierProd/CMS_CONDITIONS");
 
   std::string tag = "TrackerAlignment_v21_offline";
-  cond::Time_t start = boost::lexical_cast<unsigned long long>(294034);
-  cond::Time_t end = boost::lexical_cast<unsigned long long>(305898);
+  cond::Time_t start = static_cast<unsigned long long>(294034);
+  cond::Time_t end = static_cast<unsigned long long>(305898);
 
   std::cout << "## Alignment Histos" << std::endl;
 
diff --git a/CondCore/BeamSpotPlugins/test/testBeamSpotPayloadInspector.cpp b/CondCore/BeamSpotPlugins/test/testBeamSpotPayloadInspector.cpp
index 6fc591f7a4be5..4a0741a2a7b3f 100644
--- a/CondCore/BeamSpotPlugins/test/testBeamSpotPayloadInspector.cpp
+++ b/CondCore/BeamSpotPlugins/test/testBeamSpotPayloadInspector.cpp
@@ -27,8 +27,8 @@ int main(int argc, char** argv) {
   // BeamSpot
 
   std::string tag = "BeamSpotObjects_PCL_byLumi_v0_prompt";
-  cond::Time_t start = boost::lexical_cast<unsigned long long>(1406876667347162);
-  //cond::Time_t end = boost::lexical_cast<unsigned long long>(1406876667347162);
+  cond::Time_t start = static_cast<unsigned long long>(1406876667347162);
+  //cond::Time_t end = static_cast<unsigned long long>(1406876667347162);
 
   edm::LogPrint("testBeamSpotPayloadInspector") << "## Exercising BeamSpot plots " << std::endl;
 
@@ -37,7 +37,7 @@ int main(int argc, char** argv) {
   edm::LogPrint("testBeamSpotPayloadInspector") << histoParameters.data() << std::endl;
 
   tag = "BeamSpotOnlineTestLegacy";
-  start = boost::lexical_cast<unsigned long long>(1443392479297557);
+  start = static_cast<unsigned long long>(1443392479297557);
 
   edm::LogPrint("testBeamSpotPayloadInspector") << "## Exercising BeamSpotOnline plots " << std::endl;
 
diff --git a/CondCore/DBOutputService/src/OnlineDBOutputService.cc b/CondCore/DBOutputService/src/OnlineDBOutputService.cc
index 3896bfc7e8aa0..20d53634e9950 100644
--- a/CondCore/DBOutputService/src/OnlineDBOutputService.cc
+++ b/CondCore/DBOutputService/src/OnlineDBOutputService.cc
@@ -69,8 +69,8 @@ namespace cond {
     if (!std::getline(sinfo, slumi, ',')) {
       throw Exception("Can't get lumi id from OMS Service.");
     }
-    unsigned int run = boost::lexical_cast<unsigned int>(srun);
-    unsigned int lumi = boost::lexical_cast<unsigned int>(slumi);
+    unsigned int run = std::stoul(srun);
+    unsigned int lumi = std::stoul(slumi);
     lastLumiProcessed = cond::time::lumiTime(run, lumi);
     return lastLumiProcessed;
   }
diff --git a/CondCore/HLTPlugins/test/testAlCaRecoTriggerBitsPayloadInspector.cpp b/CondCore/HLTPlugins/test/testAlCaRecoTriggerBitsPayloadInspector.cpp
index d08272a31ec45..4eb5a7ecf29e7 100644
--- a/CondCore/HLTPlugins/test/testAlCaRecoTriggerBitsPayloadInspector.cpp
+++ b/CondCore/HLTPlugins/test/testAlCaRecoTriggerBitsPayloadInspector.cpp
@@ -22,8 +22,8 @@ int main(int argc, char** argv) {
   std::string connectionString("frontier://FrontierProd/CMS_CONDITIONS");
 
   std::string tag = "AlCaRecoHLTpaths8e29_1e31_v7_hlt";
-  cond::Time_t start = boost::lexical_cast<unsigned long long>(270000);
-  cond::Time_t end = boost::lexical_cast<unsigned long long>(304820);
+  cond::Time_t start = static_cast<unsigned long long>(270000);
+  cond::Time_t end = static_cast<unsigned long long>(304820);
 
   std::cout << "## AlCaRecoTriggerBit Histos" << std::endl;
 
diff --git a/CondCore/RunInfoPlugins/test/testRunInfoPayloadInspector.cpp b/CondCore/RunInfoPlugins/test/testRunInfoPayloadInspector.cpp
index dc78079b886b4..5bd13a5c89358 100644
--- a/CondCore/RunInfoPlugins/test/testRunInfoPayloadInspector.cpp
+++ b/CondCore/RunInfoPlugins/test/testRunInfoPayloadInspector.cpp
@@ -22,8 +22,8 @@ int main(int argc, char** argv) {
   std::string connectionString("frontier://FrontierProd/CMS_CONDITIONS");
 
   std::string tag = "runinfo_31X_hlt";
-  cond::Time_t start = boost::lexical_cast<unsigned long long>(311950);
-  cond::Time_t end = boost::lexical_cast<unsigned long long>(312237);
+  cond::Time_t start = static_cast<unsigned long long>(311950);
+  cond::Time_t end = static_cast<unsigned long long>(312237);
 
   std::cout << "## RunInfo testing" << std::endl;
 
diff --git a/CondCore/SiPixelPlugins/interface/SiPixelGainCalibHelper.h b/CondCore/SiPixelPlugins/interface/SiPixelGainCalibHelper.h
index 5f8598040d07f..824c54cc592eb 100644
--- a/CondCore/SiPixelPlugins/interface/SiPixelGainCalibHelper.h
+++ b/CondCore/SiPixelPlugins/interface/SiPixelGainCalibHelper.h
@@ -426,7 +426,7 @@ namespace gainCalibHelper {
       auto paramValues = cond::payloadInspector::PlotBase::inputParamValues();
       auto ip = paramValues.find("SetLog");
       if (ip != paramValues.end()) {
-        auto answer = boost::lexical_cast<std::string>(ip->second);
+        auto answer = ip->second;
         if (!SiPixelPI::checkAnswerOK(answer, setLog)) {
           throw cms::Exception(label_)
               << "\nERROR: " << answer
@@ -590,7 +590,7 @@ namespace gainCalibHelper {
       auto paramValues = cond::payloadInspector::PlotBase::inputParamValues();
       auto ip = paramValues.find("SetLog");
       if (ip != paramValues.end()) {
-        auto answer = boost::lexical_cast<std::string>(ip->second);
+        auto answer = ip->second;
         if (!SiPixelPI::checkAnswerOK(answer, setLog)) {
           throw cms::Exception(label_)
               << "\nERROR: " << answer
diff --git a/CondCore/SiPixelPlugins/plugins/SiPixelFEDChannelContainer_PayloadInspector.cc b/CondCore/SiPixelPlugins/plugins/SiPixelFEDChannelContainer_PayloadInspector.cc
index fd440af137345..1839bdf4fe5e5 100644
--- a/CondCore/SiPixelPlugins/plugins/SiPixelFEDChannelContainer_PayloadInspector.cc
+++ b/CondCore/SiPixelPlugins/plugins/SiPixelFEDChannelContainer_PayloadInspector.cc
@@ -82,7 +82,7 @@ namespace {
       auto paramValues = PlotBase::inputParamValues();
       auto ip = paramValues.find("Scenarios");
       if (ip != paramValues.end()) {
-        auto input = boost::lexical_cast<std::string>(ip->second);
+        auto input = ip->second;
         typedef boost::tokenizer<boost::char_separator<char>> tokenizer;
         boost::char_separator<char> sep{","};
         tokenizer tok{input, sep};
diff --git a/CondCore/SiPixelPlugins/test/testSiPixelPayloadInspector.cpp b/CondCore/SiPixelPlugins/test/testSiPixelPayloadInspector.cpp
index 8a79edc14d72a..7f3871312afc2 100644
--- a/CondCore/SiPixelPlugins/test/testSiPixelPayloadInspector.cpp
+++ b/CondCore/SiPixelPlugins/test/testSiPixelPayloadInspector.cpp
@@ -33,8 +33,8 @@ int main(int argc, char** argv) {
   // Lorentz Angle
 
   std::string tag = "SiPixelLorentzAngle_v11_offline";
-  cond::Time_t start = boost::lexical_cast<unsigned long long>(303790);
-  cond::Time_t end = boost::lexical_cast<unsigned long long>(324245);
+  cond::Time_t start = static_cast<unsigned long long>(303790);
+  cond::Time_t end = static_cast<unsigned long long>(324245);
 
   edm::LogPrint("testSiPixelPayloadInspector") << "## Exercising Lorentz Angle plots " << std::endl;
 
@@ -68,7 +68,7 @@ int main(int argc, char** argv) {
   // 2 tags comparisons
 
   std::string tag2 = "SiPixelLorentzAngle_2016_ultralegacymc_v2";
-  cond::Time_t start2 = boost::lexical_cast<unsigned long long>(1);
+  cond::Time_t start2 = static_cast<unsigned long long>(1);
 
   SiPixelLorentzAngleValueComparisonTwoTags histo6;
   histo6.process(connectionString, PI::mk_input(tag, start, start, tag2, start2, start2));
@@ -81,8 +81,8 @@ int main(int argc, char** argv) {
   // SiPixelQuality
 
   tag = "SiPixelQuality_forDigitizer_phase1_2018_permanentlyBad";
-  start = boost::lexical_cast<unsigned long long>(1);
-  end = boost::lexical_cast<unsigned long long>(1);
+  start = static_cast<unsigned long long>(1);
+  end = static_cast<unsigned long long>(1);
 
   edm::LogPrint("testSiPixelPayloadInspector") << "## Exercising SiPixelQuality plots " << std::endl;
 
@@ -97,8 +97,8 @@ int main(int argc, char** argv) {
   // SiPixelGainCalibrationOffline
 
   tag = "SiPixelGainCalibration_2009runs_express";
-  start = boost::lexical_cast<unsigned long long>(312203);
-  end = boost::lexical_cast<unsigned long long>(312203);
+  start = static_cast<unsigned long long>(312203);
+  end = static_cast<unsigned long long>(312203);
 
   edm::LogPrint("testSiPixelPayloadInspector") << "## Exercising SiPixelGainCalibrationOffline plots " << std::endl;
 
@@ -118,7 +118,7 @@ int main(int argc, char** argv) {
   histo13.process(connectionString, PI::mk_input(tag, start, end));
   edm::LogPrint("testSiPixelPayloadInspector") << histo13.data() << std::endl;
 
-  end = boost::lexical_cast<unsigned long long>(326851);
+  end = static_cast<unsigned long long>(326851);
 
   SiPixelGainCalibOfflinePedestalComparisonSingleTag histo14;
   histo14.process(connectionString, PI::mk_input(tag, start, end));
@@ -143,8 +143,8 @@ int main(int argc, char** argv) {
   // SiPixelTemplates
 
   tag = "SiPixelTemplateDBObject38Tv3_express";
-  start = boost::lexical_cast<unsigned long long>(326083);
-  end = boost::lexical_cast<unsigned long long>(326083);
+  start = static_cast<unsigned long long>(326083);
+  end = static_cast<unsigned long long>(326083);
 
   edm::LogPrint("testSiPixelPayloadInspector") << "## Exercising SiPixelTemplates plots " << std::endl;
 
@@ -177,8 +177,8 @@ int main(int argc, char** argv) {
   // SiPixelGenErrors
 
   tag = "SiPixelGenErrorDBObject_phase1_BoR3_HV350_Tr2000";
-  start = boost::lexical_cast<unsigned long long>(1);
-  end = boost::lexical_cast<unsigned long long>(1);
+  start = static_cast<unsigned long long>(1);
+  end = static_cast<unsigned long long>(1);
 
   edm::LogPrint("testSiPixelPayloadInspector") << "## Exercising SiPixelGenErrors plots " << std::endl;
 
@@ -193,8 +193,8 @@ int main(int argc, char** argv) {
   // SiPixelQualityProbabilities
 
   tag = "SiPixelQualityProbabilities_UltraLegacy2018_v0_mc";
-  start = boost::lexical_cast<unsigned long long>(1);
-  end = boost::lexical_cast<unsigned long long>(1);
+  start = static_cast<unsigned long long>(1);
+  end = static_cast<unsigned long long>(1);
 
   edm::LogPrint("testSiPixelPayloadInspector") << "## Exercising SiPixelQualityProbabilities plots " << std::endl;
 
@@ -205,8 +205,8 @@ int main(int argc, char** argv) {
   // SiPixelDynamicInefficiency
 
   tag = "SiPixelDynamicInefficiency_PhaseI_v9";
-  start = boost::lexical_cast<unsigned long long>(1);
-  end = boost::lexical_cast<unsigned long long>(1);
+  start = static_cast<unsigned long long>(1);
+  end = static_cast<unsigned long long>(1);
 
   edm::LogPrint("testSiPixelPayloadInspector") << "## Exercising SiPixeDynamicInefficiency plots " << std::endl;
 
@@ -215,7 +215,7 @@ int main(int argc, char** argv) {
   edm::LogPrint("testSiPixelPayloadInspector") << histo26.data() << std::endl;
 
   tag2 = "SiPixelDynamicInefficiency_PhaseI_v6";
-  start2 = boost::lexical_cast<unsigned long long>(1);
+  start2 = static_cast<unsigned long long>(1);
 
   SiPixelFullIneffROCsMapCompareTwoTags histo27;
   histo27.process(connectionString, PI::mk_input(tag, start, start, tag2, start2, start2));
diff --git a/CondCore/SiStripPlugins/plugins/SiStripApvGain_PayloadInspector.cc b/CondCore/SiStripPlugins/plugins/SiStripApvGain_PayloadInspector.cc
index bc21118b11bc0..dc2b59002db67 100644
--- a/CondCore/SiStripPlugins/plugins/SiStripApvGain_PayloadInspector.cc
+++ b/CondCore/SiStripPlugins/plugins/SiStripApvGain_PayloadInspector.cc
@@ -566,7 +566,7 @@ namespace {
       auto paramValues = PlotBase::inputParamValues();
       auto ip = paramValues.find("nsigma");
       if (ip != paramValues.end()) {
-        nsigma = boost::lexical_cast<unsigned int>(ip->second);
+        nsigma = std::stoul(ip->second);
       }
 
       // trick to deal with the multi-ioved tag and two tag case at the same time
@@ -674,7 +674,7 @@ namespace {
       auto paramValues = PlotBase::inputParamValues();
       auto ip = paramValues.find("nsigma");
       if (ip != paramValues.end()) {
-        nsigma = boost::lexical_cast<unsigned int>(ip->second);
+        nsigma = std::stoul(ip->second);
         edm::LogPrint("SiStripApvGain_PayloadInspector")
             << "using custom z-axis saturation: " << nsigma << " sigmas" << std::endl;
       } else {
diff --git a/CondCore/SiStripPlugins/plugins/SiStripNoises_PayloadInspector.cc b/CondCore/SiStripPlugins/plugins/SiStripNoises_PayloadInspector.cc
index f367b6ab14a05..213e1c848a583 100644
--- a/CondCore/SiStripPlugins/plugins/SiStripNoises_PayloadInspector.cc
+++ b/CondCore/SiStripPlugins/plugins/SiStripNoises_PayloadInspector.cc
@@ -117,7 +117,7 @@ namespace {
       auto paramValues = PlotBase::inputParamValues();
       auto ip = paramValues.find("DetIds");
       if (ip != paramValues.end()) {
-        auto input = boost::lexical_cast<std::string>(ip->second);
+        auto input = ip->second;
         typedef boost::tokenizer<boost::char_separator<char>> tokenizer;
         boost::char_separator<char> sep{","};
         tokenizer tok{input, sep};
@@ -316,7 +316,7 @@ namespace {
         auto paramValues = PlotBase::inputParamValues();
         auto ip = paramValues.find("DetId");
         if (ip != paramValues.end()) {
-          the_detid = boost::lexical_cast<unsigned int>(ip->second);
+          the_detid = std::stoul(ip->second);
         }
 
         if (payload.get()) {
@@ -962,7 +962,7 @@ namespace {
       auto paramValues = PlotBase::inputParamValues();
       auto ip = paramValues.find("nsigma");
       if (ip != paramValues.end()) {
-        nsigma = boost::lexical_cast<unsigned int>(ip->second);
+        nsigma = std::stoul(ip->second);
       }
 
       // trick to deal with the multi-ioved tag and two tag case at the same time
diff --git a/CondCore/SiStripPlugins/plugins/SiStripPedestals_PayloadInspector.cc b/CondCore/SiStripPlugins/plugins/SiStripPedestals_PayloadInspector.cc
index 862300c85b89c..19089ff7b30ad 100644
--- a/CondCore/SiStripPlugins/plugins/SiStripPedestals_PayloadInspector.cc
+++ b/CondCore/SiStripPlugins/plugins/SiStripPedestals_PayloadInspector.cc
@@ -116,7 +116,7 @@ namespace {
       auto paramValues = PlotBase::inputParamValues();
       auto ip = paramValues.find("DetIds");
       if (ip != paramValues.end()) {
-        auto input = boost::lexical_cast<std::string>(ip->second);
+        auto input = ip->second;
         typedef boost::tokenizer<boost::char_separator<char>> tokenizer;
         boost::char_separator<char> sep{","};
         tokenizer tok{input, sep};
@@ -315,7 +315,7 @@ namespace {
         auto paramValues = PlotBase::inputParamValues();
         auto ip = paramValues.find("DetId");
         if (ip != paramValues.end()) {
-          the_detid = boost::lexical_cast<unsigned int>(ip->second);
+          the_detid = std::stoul(ip->second);
         }
 
         if (payload.get()) {
diff --git a/CondCore/SiStripPlugins/test/testSiStripPayloadInspector.cpp b/CondCore/SiStripPlugins/test/testSiStripPayloadInspector.cpp
index ec3e2f0715e65..dad2e4c07b799 100644
--- a/CondCore/SiStripPlugins/test/testSiStripPayloadInspector.cpp
+++ b/CondCore/SiStripPlugins/test/testSiStripPayloadInspector.cpp
@@ -31,8 +31,9 @@ int main(int argc, char** argv) {
   // Gains
 
   std::string tag = "SiStripApvGain_FromParticles_GR10_v11_offline";
-  cond::Time_t start = boost::lexical_cast<unsigned long long>(132440);
-  cond::Time_t end = boost::lexical_cast<unsigned long long>(285368);
+
+  cond::Time_t start = static_cast<unsigned long long>(132440);
+  cond::Time_t end = static_cast<unsigned long long>(285368);
   py::dict inputs;
 
   edm::LogPrint("testSiStripPayloadInspector") << "## Exercising Gains plots " << std::endl;
@@ -72,8 +73,8 @@ int main(int argc, char** argv) {
   // Noise
 
   tag = "SiStripNoise_GR10_v1_hlt";
-  start = boost::lexical_cast<unsigned long long>(312968);
-  end = boost::lexical_cast<unsigned long long>(313120);
+  start = static_cast<unsigned long long>(312968);
+  end = static_cast<unsigned long long>(313120);
 
   edm::LogPrint("testSiStripPayloadInspector") << "## Exercising Noise plots " << std::endl;
 
@@ -98,8 +99,8 @@ int main(int argc, char** argv) {
   // Pedestals
 
   tag = "SiStripPedestals_v2_prompt";
-  start = boost::lexical_cast<unsigned long long>(303420);
-  end = boost::lexical_cast<unsigned long long>(313120);
+  start = static_cast<unsigned long long>(303420);
+  end = static_cast<unsigned long long>(313120);
 
   edm::LogPrint("testSiStripPayloadInspector") << "## Exercising Pedestal plots " << std::endl;
 
@@ -121,8 +122,8 @@ int main(int argc, char** argv) {
   //Latency
 
   tag = "SiStripLatency_v2_prompt";
-  start = boost::lexical_cast<unsigned long long>(315347);
-  end = boost::lexical_cast<unsigned long long>(316675);
+  start = static_cast<unsigned long long>(315347);
+  end = static_cast<unsigned long long>(316675);
 
   edm::LogPrint("testSiStripPayloadInspector") << "## Exercising Latency plots " << std::endl;
 
@@ -136,8 +137,8 @@ int main(int argc, char** argv) {
 
   //Threshold
   tag = "SiStripThreshold_v1_prompt";
-  start = boost::lexical_cast<unsigned long long>(315352);
-  end = boost::lexical_cast<unsigned long long>(315460);
+  start = static_cast<unsigned long long>(315352);
+  end = static_cast<unsigned long long>(315460);
 
   edm::LogPrint("testSiStripPayloadInspector") << "## Exercising Threshold plots " << std::endl;
 
@@ -147,8 +148,8 @@ int main(int argc, char** argv) {
 
   // test SiStripTkMaps
   tag = "SiStripBadComponents_startupMC_for2017_v1_mc";
-  start = boost::lexical_cast<unsigned long long>(1);
-  end = boost::lexical_cast<unsigned long long>(1);
+  start = static_cast<unsigned long long>(1);
+  end = static_cast<unsigned long long>(1);
 
   edm::LogPrint("testSiStripPayloadInspector") << "## Exercising SiStripTkMaps plots " << std::endl;
 
diff --git a/CondCore/Utilities/bin/conddb_test_read.cpp b/CondCore/Utilities/bin/conddb_test_read.cpp
index a4024d9fac3b7..2cbb9d44c4672 100644
--- a/CondCore/Utilities/bin/conddb_test_read.cpp
+++ b/CondCore/Utilities/bin/conddb_test_read.cpp
@@ -53,7 +53,7 @@ int cond::TestReadUtilities::execute() {
     std::string siovs = getOptionValue<std::string>("iovs");
     tokenizer tok(siovs);
     for (auto &t : tok) {
-      iovs.push_back(boost::lexical_cast<unsigned long long>(t));
+      iovs.push_back(std::stoull(t));
     }
   }
 
diff --git a/CondCore/Utilities/src/CondDBFetch.cc b/CondCore/Utilities/src/CondDBFetch.cc
index 25aa9d1e16edd..a0c6657cd3b79 100644
--- a/CondCore/Utilities/src/CondDBFetch.cc
+++ b/CondCore/Utilities/src/CondDBFetch.cc
@@ -344,9 +344,7 @@ namespace cond {
       std::string payloadTypeName;
       bool found = session.fetchPayloadData(payloadId, payloadTypeName, data, streamerInfo);
       if (!found)
-        throwException(
-            "Payload with id " + boost::lexical_cast<std::string>(payloadId) + " has not been found in the database.",
-            "fetch");
+        throwException("Payload with id " + payloadId + " has not been found in the database.", "fetch");
       return fetchOne(payloadTypeName, data, streamerInfo, payloadPtr);
     }
 
diff --git a/CondCore/Utilities/test/testPngHistograms.cpp b/CondCore/Utilities/test/testPngHistograms.cpp
index f527f6e4ce27e..0ecbfef087a3b 100644
--- a/CondCore/Utilities/test/testPngHistograms.cpp
+++ b/CondCore/Utilities/test/testPngHistograms.cpp
@@ -23,7 +23,7 @@ int main(int argc, char** argv) {
   std::string connectionString("frontier://FrontierProd/CMS_CONDITIONS");
 
   std::string tag = std::string("BasicPayload_v10.0");
-  cond::Time_t since = boost::lexical_cast<unsigned long long>("901");
+  cond::Time_t since = std::stoull("901");
 
   std::cout << "## PNG Histo" << std::endl;