diff --git a/pip/grpcio.file b/pip/grpcio.file
index 19a0d366c2b..793f98d0a31 100644
--- a/pip/grpcio.file
+++ b/pip/grpcio.file
@@ -1 +1,2 @@
 Requires: py3-six re2
+%define PipPreBuild export GRPC_PYTHON_BUILD_SYSTEM_OPENSSL=true