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<!DOCTYPE html>
<html lang="zh-CN">
<head>
<meta charset="UTF-8">
<meta name="viewport" content="width=device-width, initial-scale=1.0">
<title>TSMPdb - 肿瘤特异性膜蛋白数据库</title>
<link rel="stylesheet" href="style.css">
<style>
* {
margin: 0;
padding: 0;
box-sizing: border-box;
}
body {
font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, Oxygen, Ubuntu, Cantarell, sans-serif;
line-height: 1.6;
color: #333;
overflow-x: hidden;
}
/* Hero Section */
.hero {
background: linear-gradient(135deg, #667eea 0%, #764ba2 100%);
min-height: 100vh;
display: flex;
align-items: center;
justify-content: center;
position: relative;
color: white;
text-align: center;
}
.hero::before {
content: '';
position: absolute;
top: 0;
left: 0;
right: 0;
bottom: 0;
background: url('data:image/svg+xml,<svg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 100 100"><defs><pattern id="grid" width="10" height="10" patternUnits="userSpaceOnUse"><path d="M 10 0 L 0 0 0 10" fill="none" stroke="rgba(255,255,255,0.1)" stroke-width="0.5"/></pattern></defs><rect width="100" height="100" fill="url(%23grid)"/></svg>');
opacity: 0.3;
}
.hero-content {
max-width: 800px;
padding: 0 20px;
position: relative;
z-index: 1;
}
.hero h1 {
font-size: 3.5rem;
font-weight: 700;
margin-bottom: 1rem;
animation: fadeInUp 1s ease-out;
}
.hero .subtitle {
font-size: 1.3rem;
margin-bottom: 2rem;
opacity: 0.9;
animation: fadeInUp 1s ease-out 0.3s both;
}
.hero .description {
font-size: 1.1rem;
margin-bottom: 3rem;
opacity: 0.8;
animation: fadeInUp 1s ease-out 0.6s both;
}
.cta-buttons {
display: flex;
gap: 1rem;
justify-content: center;
flex-wrap: wrap;
animation: fadeInUp 1s ease-out 0.9s both;
}
.btn {
padding: 15px 30px;
border: none;
border-radius: 50px;
font-size: 1.1rem;
font-weight: 600;
cursor: pointer;
transition: all 0.3s ease;
text-decoration: none;
display: inline-block;
}
.btn-primary {
background: white;
color: #667eea;
}
.btn-primary:hover {
transform: translateY(-2px);
box-shadow: 0 10px 25px rgba(0,0,0,0.2);
}
.btn-secondary {
background: transparent;
color: white;
border: 2px solid white;
}
.btn-secondary:hover {
background: white;
color: #667eea;
transform: translateY(-2px);
}
/* Features Section */
.features {
padding: 100px 20px;
background: #f8fafc;
}
.container {
max-width: 1200px;
margin: 0 auto;
}
.section-title {
text-align: center;
font-size: 2.5rem;
font-weight: 700;
margin-bottom: 3rem;
color: #2d3748;
}
.features-grid {
display: grid;
grid-template-columns: repeat(auto-fit, minmax(300px, 1fr));
gap: 3rem;
margin-top: 4rem;
}
.feature-card {
background: white;
padding: 2.5rem;
border-radius: 20px;
box-shadow: 0 10px 30px rgba(0,0,0,0.1);
transition: all 0.3s ease;
text-align: center;
}
.feature-card:hover {
transform: translateY(-10px);
box-shadow: 0 20px 40px rgba(0,0,0,0.15);
}
.feature-icon {
width: 80px;
height: 80px;
margin: 0 auto 1.5rem;
background: linear-gradient(135deg, #667eea, #764ba2);
border-radius: 50%;
display: flex;
align-items: center;
justify-content: center;
font-size: 2rem;
}
.feature-card h3 {
font-size: 1.5rem;
font-weight: 600;
margin-bottom: 1rem;
color: #2d3748;
}
.feature-card p {
color: #718096;
line-height: 1.7;
}
/* Technology Section */
.technology {
padding: 100px 20px;
background: white;
}
.tech-grid {
display: grid;
grid-template-columns: repeat(auto-fit, minmax(250px, 1fr));
gap: 2rem;
margin-top: 3rem;
}
.tech-item {
padding: 2rem;
border: 2px solid #e2e8f0;
border-radius: 15px;
transition: all 0.3s ease;
text-align: center;
}
.tech-item:hover {
border-color: #667eea;
transform: translateY(-5px);
}
.tech-item h4 {
font-size: 1.3rem;
font-weight: 600;
margin-bottom: 1rem;
color: #2d3748;
}
/* Footer */
.footer {
background: #2d3748;
color: white;
padding: 60px 20px 30px;
text-align: center;
}
.footer-content {
max-width: 600px;
margin: 0 auto;
}
.footer h3 {
font-size: 1.5rem;
margin-bottom: 1rem;
}
.footer-links {
display: flex;
justify-content: center;
gap: 2rem;
margin: 2rem 0;
flex-wrap: wrap;
}
.footer-links a {
color: #90cdf4;
text-decoration: none;
font-weight: 500;
}
.footer-links a:hover {
color: white;
}
/* Animations */
@keyframes fadeInUp {
from {
opacity: 0;
transform: translateY(30px);
}
to {
opacity: 1;
transform: translateY(0);
}
}
/* Responsive */
@media (max-width: 768px) {
.hero h1 {
font-size: 2.5rem;
}
.hero .subtitle {
font-size: 1.1rem;
}
.cta-buttons {
flex-direction: column;
align-items: center;
}
.section-title {
font-size: 2rem;
}
.features-grid,
.tech-grid {
grid-template-columns: 1fr;
}
}
</style>
</head>
<body>
<header>
<nav class="container">
<a href="#" class="logo">ImmunoAI</a>
<ul class="nav-links">
<li><a href="index.html">首页</a></li>
<li><a href="index.html#features">核心优势</a></li>
<li class="dropdown">
<a href="#services">数据资源</a>
<div class="dropdown-content">
<a href="tsmpdb.html">肿瘤膜蛋白数据库</a>
<a href="neodb_page.html">肿瘤新抗原数据库</a>
</div>
</li>
<li class="dropdown">
<a href="#tools">AI设计工具</a>
<div class="dropdown-content">
<a href="antibody_design.html">抗体设计</a>
<a href="tcr_design.html">TCR设计</a>
<a href="tcr_design.html">定向进化</a>
</div>
</li>
<li><a href="contact_page.html">联系我们</a></li>
</ul>
</nav>
</header>
<!-- Hero Section -->
<section class="hero">
<div class="hero-content">
<h1>TSMPdb</h1>
<p class="subtitle">肿瘤特异性膜蛋白数据库</p>
<p class="description">
整合多组学数据,系统注释肿瘤特异性膜蛋白基因,助力精准肿瘤靶点筛选与研究。
</p>
<div class="cta-buttons">
<a href="contact_page.html" class="btn btn-primary">立即使用平台</a>
<button id="learn-more-btn" class="btn btn-secondary" onclick="window.location.href = 'tsmpdb.html#features';">了解更多</button>
</div>
</div>
</section>
<!-- Features Section -->
<section class="features" id="features">
<div class="container">
<h2 class="section-title">数据来源与处理</h2>
<div class="features-grid">
<div class="feature-card">
<div class="feature-icon">🗂️</div>
<h3>数据采集</h3>
<p>整合公共数据库、文献报道及软件预测获得膜蛋白编码基因</p>
</div>
<div class="feature-card">
<div class="feature-icon">📊</div>
<h3>数据注释</h3>
<p>包括三维结构、膜外区域、可接近性等详尽注释</p>
</div>
<div class="feature-card">
<div class="feature-icon">📚</div>
<h3>数据类型</h3>
<p>包括单细胞转录组、常规组织转录组、蛋白组数据等</p>
</div>
<div class="feature-card">
<div class="feature-icon">🎯</div>
<h3>靶向价值计算</h3>
<p>综合评估基因表达的稳定性、特异性、覆盖度及其与干性的相关性</p>
</div>
<div class="feature-card">
<div class="feature-icon">🧩</div>
<h3>靶向难度计算</h3>
<p>综合评估蛋白胞外区潜在表位数量、过翻译修饰情况及蛋白表面可接近性</p>
</div>
<div class="feature-card">
<div class="feature-icon">🤖</div>
<h3>靶点筛选</h3>
<p>依据多指标综合筛选符合条件的肿瘤膜蛋白靶点</p>
</div>
</div>
</div>
</section>
<!-- Technology Section -->
<section class="technology">
<div class="container">
<h2 class="section-title">数据库功能与亮点</h2>
<div class="tech-grid">
<div class="tech-item">
<h4>多维度注释</h4>
<p>结合结构与表达信息,提供全面数据支持</p>
</div>
<div class="tech-item">
<h4>多组学整合</h4>
<p>单细胞转录组、组织转录组与蛋白组数据同步分析</p>
</div>
<div class="tech-item">
<h4>特异性筛选</h4>
<p>精准识别肿瘤特异靶点,助力精准医疗研究</p>
</div>
<div class="tech-item">
<h4>用户友好界面</h4>
<p>支持数据浏览、下载等功能</p>
</div>
</div>
</div>
</section>
<!-- Footer -->
<footer class="footer">
<div class="footer-content">
<h3>开始您的肿瘤特异性膜蛋白发现之旅</h3>
<p>TSMPdb致力于整合和注释肿瘤相关的膜蛋白编码基因信息,结合多组学数据,筛选肿瘤特异的膜蛋白靶点,支持肿瘤靶向研究和新药开发</p>
<div class="footer-links">
<a href="contact_page.html">联系我们</a>
</div>
<p style="margin-top: 2rem; opacity: 0.7;">© 2025 TSMPdb Team. All rights reserved.</p>
</div>
</footer>
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