diff --git a/setup.py b/setup.py
index 6c70ab40749..fae677f6c6b 100644
--- a/setup.py
+++ b/setup.py
@@ -5,7 +5,7 @@
 README = open(os.path.join(here, 'README.md')).read()
 CHANGES = open(os.path.join(here, 'CHANGES.rst')).read()
 # Edit Snovault version after the `@` here, can be a branch or tag
-SNOVAULT_DEP = "git+https://github.com/ENCODE-DCC/snovault.git@1.0.62"
+SNOVAULT_DEP = "git+https://github.com/ENCODE-DCC/snovault.git@upgrade-validator-sno2"
 
 INSTALL_REQUIRES = [
     "PasteDeploy==2.1.0",
@@ -21,7 +21,7 @@
     "elasticsearch==5.4.0",
     "future==0.18.2",
     "humanfriendly==6.1",
-    "jsonschema_serialize_fork==2.1.1",
+    "jsonschema[format]==4.4.0",
     "loremipsum==1.0.5",
     "passlib==1.7.2",
     "psutil==5.6.7",
@@ -32,7 +32,7 @@
     "pyramid==1.10.4",
     "python-magic==0.4.15",
     "pytz==2019.3",
-    "rdflib-jsonld==0.4.0",
+    "rdflib-jsonld==0.6.0",
     "rdflib==4.2.2",
     "repoze.debug==1.1",
     "rfc3987==1.3.8",
diff --git a/src/encoded/auth0.py b/src/encoded/auth0.py
index 3bb37232adc..29bf47f0d3c 100644
--- a/src/encoded/auth0.py
+++ b/src/encoded/auth0.py
@@ -7,7 +7,7 @@
 from snovault.schema_utils import validate_request
 from pyramid.authentication import CallbackAuthenticationPolicy
 from encoded.types.user import User
-from jsonschema_serialize_fork.exceptions import ValidationError
+from jsonschema.exceptions import ValidationError
 from pyramid.httpexceptions import (
     HTTPBadRequest,
     HTTPInternalServerError,
diff --git a/src/encoded/schema_formats.py b/src/encoded/schema_formats.py
index 46eb9f37dde..35a082da977 100644
--- a/src/encoded/schema_formats.py
+++ b/src/encoded/schema_formats.py
@@ -1,6 +1,6 @@
 import re
 import rfc3987
-from jsonschema_serialize_fork import FormatChecker
+from jsonschema import FormatChecker
 from pyramid.threadlocal import get_current_request
 from uuid import UUID
 
diff --git a/src/encoded/schemas/access_key.json b/src/encoded/schemas/access_key.json
index 3c843bdba16..d9d04242879 100644
--- a/src/encoded/schemas/access_key.json
+++ b/src/encoded/schemas/access_key.json
@@ -1,7 +1,7 @@
 {
     "title": "Admin access key",
-    "id": "/profiles/access_key_admin.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/access_key_admin.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "required": [],
     "additionalProperties": false,
     "mixinProperties": [
diff --git a/src/encoded/schemas/aggregate_series.json b/src/encoded/schemas/aggregate_series.json
index 9c82ba17726..798fca46be0 100644
--- a/src/encoded/schemas/aggregate_series.json
+++ b/src/encoded/schemas/aggregate_series.json
@@ -1,8 +1,8 @@
 {
     "title": "Aggregate series",
     "description": "Schema for submitting metadata for an aggregate series.",
-    "id": "/profiles/aggregate_series.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/aggregate_series.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": [ "award", "lab"],
     "identifyingProperties": ["uuid", "accession" , "aliases"],
@@ -21,7 +21,7 @@
         { "$ref": "series.json#/properties" },
         { "$ref": "mixins.json#/submitter_comment" }
     ],
-    "dependencies": {
+    "dependentSchemas": {
         "status": {
             "oneOf": [
                 {
diff --git a/src/encoded/schemas/analysis.json b/src/encoded/schemas/analysis.json
index 445c904ed36..7ec5281e856 100644
--- a/src/encoded/schemas/analysis.json
+++ b/src/encoded/schemas/analysis.json
@@ -2,8 +2,8 @@
     "title": "Analysis",
     "description": "Schema for grouping files into one analysis.",
     "comment": "An analysis is typically performed on one experiments and is initially designed to group only files from a single experiment.",
-    "id": "/profiles/analysis.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/analysis.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["files"],
     "identifyingProperties": ["uuid", "accession", "aliases"],
@@ -18,7 +18,6 @@
         { "$ref": "mixins.json#/notes" },
         { "$ref": "mixins.json#/documents" }
     ],
-    "dependencies": {},
     "properties": {
         "schema_version": {
             "default": "1"
diff --git a/src/encoded/schemas/analysis_step.json b/src/encoded/schemas/analysis_step.json
index 2d92dd31f0a..66ae412d508 100644
--- a/src/encoded/schemas/analysis_step.json
+++ b/src/encoded/schemas/analysis_step.json
@@ -1,8 +1,8 @@
 { 
     "title": "Analysis step",
     "description": "Schema for submitting a computational analysis steps as a subobject of pipeline that transforms input files to output files.",
-    "id": "/profiles/analysis_step.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/analysis_step.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["step_label", "title", "analysis_step_types", "input_file_types", "major_version"],
     "additionalProperties": false,
diff --git a/src/encoded/schemas/analysis_step_run.json b/src/encoded/schemas/analysis_step_run.json
index adfc019bc4f..bc5c6bb9e9f 100644
--- a/src/encoded/schemas/analysis_step_run.json
+++ b/src/encoded/schemas/analysis_step_run.json
@@ -1,8 +1,8 @@
 {
     "title": "Analysis step run",
     "description": "Schema for reporting the specific calculation of an analysis_step",
-    "id": "/profiles/analysis_step_run.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/analysis_step_run.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["analysis_step_version"],
     "additionalProperties": false,
diff --git a/src/encoded/schemas/analysis_step_version.json b/src/encoded/schemas/analysis_step_version.json
index 1c58b63be29..a88e0ad2ea3 100644
--- a/src/encoded/schemas/analysis_step_version.json
+++ b/src/encoded/schemas/analysis_step_version.json
@@ -1,8 +1,8 @@
 {
     "title": "Analysis step version",
     "description": "A compatible version of an analysis step.",
-    "id": "/profiles/analysis_step_version.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/analysis_step_version.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["software_versions", "analysis_step", "minor_version"],
     "additionalProperties": false,
diff --git a/src/encoded/schemas/annotation.json b/src/encoded/schemas/annotation.json
index 6afc947ff0d..f898d3c7447 100644
--- a/src/encoded/schemas/annotation.json
+++ b/src/encoded/schemas/annotation.json
@@ -1,8 +1,8 @@
 {
     "title": "Annotation",
     "description": "Schema for submitting metadata for an annotation set.",
-    "id": "/profiles/annotation.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/annotation.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": [ "award", "lab", "annotation_type"],
     "identifyingProperties": ["uuid", "accession" , "aliases"],
@@ -21,7 +21,11 @@
         { "$ref": "dataset.json#/properties" },
         { "$ref": "file_set.json#/properties" }
     ],
-    "dependencies": {
+    "dependentRequired": {
+	"relevant_timepoint": ["relevant_timepoint_units"],
+	"relevant_timepoint_units": ["relevant_timepoint"]
+    },
+    "dependentSchemas": {
         "biosample_ontology": {
             "not": {
                 "properties": {
@@ -41,8 +45,6 @@
                 }
             }
         },
-        "relevant_timepoint": ["relevant_timepoint_units"],
-        "relevant_timepoint_units": ["relevant_timepoint"],
         "status": {
             "oneOf": [
                 {
diff --git a/src/encoded/schemas/antibody_characterization.json b/src/encoded/schemas/antibody_characterization.json
index bf5c1b3f1dd..d8ec55d4d22 100644
--- a/src/encoded/schemas/antibody_characterization.json
+++ b/src/encoded/schemas/antibody_characterization.json
@@ -1,8 +1,8 @@
- {
+{
     "title": "Antibody characterization",
     "description": "Schema for submitting antibody characterization data.",
-    "id": "/profiles/antibody_characterization.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/antibody_characterization.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": [ "award", "lab", "characterizes", "target", "attachment"],
     "identifyingProperties": ["uuid", "aliases"],
@@ -20,8 +20,10 @@
         { "$ref": "mixins.json#/documents" },
         { "$ref": "mixins.json#/submitter_comment" }
     ],
-    "dependencies": {
-        "characterization_reviews": ["primary_characterization_method"],
+    "dependentRequired": {
+	"characterization_reviews": ["primary_characterization_method"]
+    },
+    "dependentSchemas": {
         "primary_characterization_method": {
             "oneOf": [
                 {
diff --git a/src/encoded/schemas/antibody_lot.json b/src/encoded/schemas/antibody_lot.json
index 36b263aac59..ba4b2f59d63 100644
--- a/src/encoded/schemas/antibody_lot.json
+++ b/src/encoded/schemas/antibody_lot.json
@@ -1,8 +1,8 @@
 {
     "title": "Antibody lot",
     "description": "Schema for submitting an antibody lot (not including target or characterization information).",
-    "id": "/profiles/antibody_lot.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/antibody_lot.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": [ "award", "lab", "product_id", "source", "lot_id", "host_organism"],
     "identifyingProperties": ["uuid","accession","aliases"],
diff --git a/src/encoded/schemas/atac_alignment_enrichment_quality_metric.json b/src/encoded/schemas/atac_alignment_enrichment_quality_metric.json
index c1c647d6100..fbf0b009b04 100644
--- a/src/encoded/schemas/atac_alignment_enrichment_quality_metric.json
+++ b/src/encoded/schemas/atac_alignment_enrichment_quality_metric.json
@@ -1,8 +1,8 @@
 {
     "title": "ATAC-seq alignment enrichment quality metric",
     "description": "Schema for ATAC-seq alignment enrichment quality metrics",
-    "id": "/profiles/atac_alignment_enrichment_quality_metric.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/atac_alignment_enrichment_quality_metric.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["step_run","quality_metric_of", "award", "lab"],
     "additionalProperties": false,
diff --git a/src/encoded/schemas/atac_alignment_quality_metric.json b/src/encoded/schemas/atac_alignment_quality_metric.json
index 3a3dd741ccb..8eb303a7518 100644
--- a/src/encoded/schemas/atac_alignment_quality_metric.json
+++ b/src/encoded/schemas/atac_alignment_quality_metric.json
@@ -1,8 +1,8 @@
 {
     "title": "ATAC-seq alignment quality metric",
     "description": "Schema for reporting ATAC-seq alignment quality metrics",
-    "id": "/profiles/atac_alignment_quality_metric.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/atac_alignment_quality_metric.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["step_run","quality_metric_of", "award", "lab"],
     "additionalProperties": false,
diff --git a/src/encoded/schemas/atac_library_complexity_quality_metric.json b/src/encoded/schemas/atac_library_complexity_quality_metric.json
index c79963dd53b..49800eaa06a 100644
--- a/src/encoded/schemas/atac_library_complexity_quality_metric.json
+++ b/src/encoded/schemas/atac_library_complexity_quality_metric.json
@@ -1,8 +1,8 @@
 {
     "title": "ATAC-seq library quality metric",
     "description": "Schema for reporting ATAC-seq library quality metrics",
-    "id": "/profiles/atac_library_complexity_quality_metric.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/atac_library_complexity_quality_metric.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["step_run","quality_metric_of", "award", "lab"],
     "additionalProperties": false,
diff --git a/src/encoded/schemas/atac_peak_enrichment_quality_metric.json b/src/encoded/schemas/atac_peak_enrichment_quality_metric.json
index 68b4a292efd..690be733160 100644
--- a/src/encoded/schemas/atac_peak_enrichment_quality_metric.json
+++ b/src/encoded/schemas/atac_peak_enrichment_quality_metric.json
@@ -1,8 +1,8 @@
 {
     "title": "ATAC-seq peak enrichment quality metric",
     "description": "Schema for reporting ATAC-seq peak enrichment quality metrics",
-    "id": "/profiles/atac_peak_enrichment_quality_metric.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/atac_peak_enrichment_quality_metric.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["step_run","quality_metric_of", "award", "lab"],
     "additionalProperties": false,
diff --git a/src/encoded/schemas/atac_replication_quality_metric.json b/src/encoded/schemas/atac_replication_quality_metric.json
index ba97fe655e8..da90158f5b6 100644
--- a/src/encoded/schemas/atac_replication_quality_metric.json
+++ b/src/encoded/schemas/atac_replication_quality_metric.json
@@ -1,8 +1,8 @@
 {
     "title": "ATAC-seq replication quality metric",
     "description": "Schema for reporting ATAC-seq replication quality metrics",
-    "id": "/profiles/atac_replication_quality_metric.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/atac_replication_quality_metric.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["step_run","quality_metric_of", "award", "lab"],
     "additionalProperties": false,
diff --git a/src/encoded/schemas/award.json b/src/encoded/schemas/award.json
index 4df5997812f..9a42ccfc08a 100644
--- a/src/encoded/schemas/award.json
+++ b/src/encoded/schemas/award.json
@@ -1,7 +1,7 @@
 {
     "title": "Grant",
-    "id": "/profiles/award.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/award.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "required": [ "name", "project", "rfa", "title"],
     "identifyingProperties": ["uuid", "name", "title"],
     "additionalProperties": false,
diff --git a/src/encoded/schemas/biosample.json b/src/encoded/schemas/biosample.json
index 8d9bf65286e..3f4c42792cc 100644
--- a/src/encoded/schemas/biosample.json
+++ b/src/encoded/schemas/biosample.json
@@ -2,8 +2,8 @@
     "title": "Biosample",
     "description": "Schema for submitting a biosample.",
     "comment": "For cultured samples this object represents unique growths or culture harvests.",
-    "id": "/profiles/biosample.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/biosample.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": [ "award", "lab", "source", "organism", "biosample_ontology"],
     "identifyingProperties": ["uuid", "accession", "aliases"],
@@ -27,7 +27,7 @@
         {"$ref": "mixins.json#/accession"},
         {"$ref": "mixins.json#/uuid"}
     ],
-    "dependencies": {
+    "dependentSchemas": {
         "biosample_ontology": {
             "not": {
                 "properties": {
@@ -976,9 +976,11 @@
                         "maximum": 100
                     }
                 },
-                "dependencies": {
-                    "expression_range_minimum": ["expression_range_maximum"],
-                    "expression_range_maximum": ["expression_range_minimum"],
+		"dependentRequired": {
+		    "expression_range_minimum": ["expression_range_maximum"],
+		    "expression_range_maximum": ["expression_range_minimum"]
+		},
+                "dependentSchemas": {
                     "expression_percentile": {
                         "not": {
                             "anyOf": [
diff --git a/src/encoded/schemas/biosample_characterization.json b/src/encoded/schemas/biosample_characterization.json
index 7456a6d9add..bb562b8556c 100644
--- a/src/encoded/schemas/biosample_characterization.json
+++ b/src/encoded/schemas/biosample_characterization.json
@@ -1,8 +1,8 @@
 {
     "title": "Biosample characterization",
     "description": "Schema for submitting biosample characterization data",
-    "id": "/profiles/biosample_characterization.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/biosample_characterization.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": [ "award", "lab", "characterizes", "attachment"],
     "identifyingProperties": ["uuid", "aliases"],
diff --git a/src/encoded/schemas/biosample_type.json b/src/encoded/schemas/biosample_type.json
index 5a4d08d5ff5..fc4a3f920fd 100644
--- a/src/encoded/schemas/biosample_type.json
+++ b/src/encoded/schemas/biosample_type.json
@@ -2,8 +2,8 @@
     "title": "Biosample Type",
     "description": "Schema for describing the type of a specific biosample.",
     "comment": "This object collects common properties of a group of similar biosamples to help reduce ambiguity and duplications. Do not submit. DCC personnel is responsible for creating and maintaining these objects",
-    "id": "/profiles/biosample_type.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/biosample_type.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["classification", "term_id", "term_name"],
     "identifyingProperties": ["aliases", "uuid"],
@@ -16,7 +16,7 @@
         {"$ref": "mixins.json#/standard_status"},
         {"$ref": "mixins.json#/uuid"}
     ],
-    "dependencies": {
+    "dependentSchemas": {
         "term_id":{
             "oneOf": [
                 { 
diff --git a/src/encoded/schemas/bismark_quality_metric.json b/src/encoded/schemas/bismark_quality_metric.json
index e42f1c17c9a..43f88a179f4 100644
--- a/src/encoded/schemas/bismark_quality_metric.json
+++ b/src/encoded/schemas/bismark_quality_metric.json
@@ -1,8 +1,8 @@
 {
     "title": "Bismark quality metric",
     "description": "Schema for reporting the specific calculation of an quality metrics",
-    "id": "/profiles/bismark_quality_metric.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/bismark_quality_metric.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["step_run", "quality_metric_of", "award", "lab"],
     "additionalProperties": false,
diff --git a/src/encoded/schemas/bru_library_quality_metric.json b/src/encoded/schemas/bru_library_quality_metric.json
index 9b58749d37f..33abaa1bca0 100644
--- a/src/encoded/schemas/bru_library_quality_metric.json
+++ b/src/encoded/schemas/bru_library_quality_metric.json
@@ -1,8 +1,8 @@
 {
     "title": "Bru library quality metric",
     "description": "Schema for reporting Bru assay library quality metric",
-    "id": "/profiles/bru_library_quality_metric.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/bru_library_quality_metric.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["step_run", "award", "lab", "quality_metric_of"],
     "additionalProperties": false,
diff --git a/src/encoded/schemas/cart.json b/src/encoded/schemas/cart.json
index 55536296fd4..9e2a777a27e 100644
--- a/src/encoded/schemas/cart.json
+++ b/src/encoded/schemas/cart.json
@@ -2,8 +2,8 @@
     "title": "Cart",
     "description": "Cart of objects aka shopping cart.",
     "comment": "This object gets connected with user objects.",
-    "id": "/profiles/cart.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/cart.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["name"],
     "identifyingProperties": ["uuid", "identifier"],
@@ -13,7 +13,7 @@
         { "$ref": "mixins.json#/submitted" },
         { "$ref": "mixins.json#/uuid" }
     ],
-    "dependencies": {
+    "dependentSchemas": {
         "status":{
             "comment": "Listed, released, or revoked carts must have a description.",
             "oneOf": [
diff --git a/src/encoded/schemas/characterization.json b/src/encoded/schemas/characterization.json
index 853c89fe99e..98884ef24f7 100644
--- a/src/encoded/schemas/characterization.json
+++ b/src/encoded/schemas/characterization.json
@@ -1,8 +1,8 @@
 {
     "title": "Base characterization",
     "description": "Schema for submitting a characterization of an object.",
-    "id": "/profiles/characterization.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/characterization.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": [ "award", "lab", "characterizes", "attachment"],
     "additionalProperties": false,
diff --git a/src/encoded/schemas/chia_pet_alignment_quality_metric.json b/src/encoded/schemas/chia_pet_alignment_quality_metric.json
index a4a3efcefd8..5d54f5fa028 100644
--- a/src/encoded/schemas/chia_pet_alignment_quality_metric.json
+++ b/src/encoded/schemas/chia_pet_alignment_quality_metric.json
@@ -1,8 +1,8 @@
 {
     "title": "ChIA-PET alignment quality metric",
     "description": "Schema for reporting ChIA-PET alignment quality metric",
-    "id": "/profiles/chia_pet_alignment_quality_metric.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/chia_pet_alignment_quality_metric.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["step_run", "award", "lab", "quality_metric_of"],
     "additionalProperties": false,
diff --git a/src/encoded/schemas/chia_pet_chr_interactions_quality_metric.json b/src/encoded/schemas/chia_pet_chr_interactions_quality_metric.json
index 3ec4f1fccbe..96d286e8386 100644
--- a/src/encoded/schemas/chia_pet_chr_interactions_quality_metric.json
+++ b/src/encoded/schemas/chia_pet_chr_interactions_quality_metric.json
@@ -1,8 +1,8 @@
 {
     "title": "ChIA-PET chromatin interactions quality metric",
     "description": "Schema for reporting ChIA-PET chromatin interactions quality metric",
-    "id": "/profiles/chia_pet_chr_interactions_quality_metric.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/chia_pet_chr_interactions_quality_metric.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["step_run", "award", "lab", "quality_metric_of"],
     "additionalProperties": false,
diff --git a/src/encoded/schemas/chia_pet_peak_enrichment_quality_metric.json b/src/encoded/schemas/chia_pet_peak_enrichment_quality_metric.json
index f285e6f1c43..bc380690b4c 100644
--- a/src/encoded/schemas/chia_pet_peak_enrichment_quality_metric.json
+++ b/src/encoded/schemas/chia_pet_peak_enrichment_quality_metric.json
@@ -1,8 +1,8 @@
 {
     "title": "ChIA-PET peak enrichment quality metric",
     "description": "Schema for reporting ChIA-PET peak enrichment quality metric",
-    "id": "/profiles/chia_pet_peak_enrichment_quality_metric.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/chia_pet_peak_enrichment_quality_metric.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["step_run", "award", "lab", "quality_metric_of"],
     "additionalProperties": false,
diff --git a/src/encoded/schemas/chip_alignment_enrichment_quality_metric.json b/src/encoded/schemas/chip_alignment_enrichment_quality_metric.json
index 79986e7dcd4..2becec7f518 100644
--- a/src/encoded/schemas/chip_alignment_enrichment_quality_metric.json
+++ b/src/encoded/schemas/chip_alignment_enrichment_quality_metric.json
@@ -1,8 +1,8 @@
 {
     "title": "ChIP-seq alignment enrichment quality metric",
     "description": "Schema for ChIP-seq alignment enrichment quality metrics",
-    "id": "/profiles/chip_alignment_enrichment_quality_metric.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/chip_alignment_enrichment_quality_metric.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["step_run","quality_metric_of", "award", "lab"],
     "additionalProperties": false,
diff --git a/src/encoded/schemas/chip_alignment_samstat_quality_metric.json b/src/encoded/schemas/chip_alignment_samstat_quality_metric.json
index 4936955fcea..e54074318c0 100644
--- a/src/encoded/schemas/chip_alignment_samstat_quality_metric.json
+++ b/src/encoded/schemas/chip_alignment_samstat_quality_metric.json
@@ -1,8 +1,8 @@
 {
     "title": "ChIP-seq alignment quality metric",
     "description": "Schema for reporting ChIP-seq alignment quality metrics",
-    "id": "/profiles/chip_alignment_samstat_quality_metric.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/chip_alignment_samstat_quality_metric.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["step_run","quality_metric_of", "award", "lab"],
     "additionalProperties": false,
diff --git a/src/encoded/schemas/chip_library_quality_metric.json b/src/encoded/schemas/chip_library_quality_metric.json
index b34a54671f6..293290809a1 100644
--- a/src/encoded/schemas/chip_library_quality_metric.json
+++ b/src/encoded/schemas/chip_library_quality_metric.json
@@ -1,8 +1,8 @@
 {
     "title": "ChIP-seq library quality metric",
     "description": "Schema for reporting ChIP-seq library quality metrics",
-    "id": "/profiles/chip_library_quality_metric.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/chip_library_quality_metric.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["step_run","quality_metric_of", "award", "lab"],
     "additionalProperties": false,
diff --git a/src/encoded/schemas/chip_peak_enrichment_quality_metric.json b/src/encoded/schemas/chip_peak_enrichment_quality_metric.json
index 73c4e206fc5..49bc38944ec 100644
--- a/src/encoded/schemas/chip_peak_enrichment_quality_metric.json
+++ b/src/encoded/schemas/chip_peak_enrichment_quality_metric.json
@@ -1,8 +1,8 @@
 {
     "title": "ChIP-seq peak enrichment quality metric",
     "description": "Schema for reporting ChIP-seq peak enrichment quality metrics",
-    "id": "/profiles/chip_peak_enrichment_quality_metric.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/chip_peak_enrichment_quality_metric.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["step_run","quality_metric_of", "award", "lab"],
     "additionalProperties": false,
diff --git a/src/encoded/schemas/chip_replication_quality_metric.json b/src/encoded/schemas/chip_replication_quality_metric.json
index 4744bf19c0c..ce665e0e006 100644
--- a/src/encoded/schemas/chip_replication_quality_metric.json
+++ b/src/encoded/schemas/chip_replication_quality_metric.json
@@ -1,8 +1,8 @@
 {
     "title": "ChIP-seq replication quality metric",
     "description": "Schema for reporting ChIP-seq replication quality metrics",
-    "id": "/profiles/chip_replication_quality_metric.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/chip_replication_quality_metric.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["step_run","quality_metric_of", "award", "lab"],
     "additionalProperties": false,
diff --git a/src/encoded/schemas/chipseq_filter_quality_metric.json b/src/encoded/schemas/chipseq_filter_quality_metric.json
index 9e4e47af29f..e6d463c9108 100644
--- a/src/encoded/schemas/chipseq_filter_quality_metric.json
+++ b/src/encoded/schemas/chipseq_filter_quality_metric.json
@@ -1,8 +1,8 @@
 {
     "title": "ChIP-seq library complexity and cross-correlation quality metric",
     "description": "Schema for reporting ChIP library complexity and cross-correlation quality metrics",
-    "id": "/profiles/chipseq_filter_quality_metric.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/chipseq_filter_quality_metric.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["step_run","quality_metric_of", "award", "lab"],
     "additionalProperties": false,
diff --git a/src/encoded/schemas/collection_series.json b/src/encoded/schemas/collection_series.json
index dd24887bbcb..7c7b2d0ed4b 100644
--- a/src/encoded/schemas/collection_series.json
+++ b/src/encoded/schemas/collection_series.json
@@ -1,8 +1,8 @@
 {
     "title": "Collection series",
     "description": "Schema for submitting metadata for a collection series.",
-    "id": "/profiles/collection_series.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/collection_series.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": [ "award", "lab"],
     "identifyingProperties": ["uuid", "accession" , "aliases"],
@@ -21,7 +21,7 @@
         { "$ref": "series.json#/properties" },
         { "$ref": "mixins.json#/submitter_comment" }
     ],
-    "dependencies": {
+    "dependentSchemas": {
         "status": {
             "oneOf": [
                 {
diff --git a/src/encoded/schemas/complexity_xcorr_quality_metric.json b/src/encoded/schemas/complexity_xcorr_quality_metric.json
index 255577027b2..766dd5ae131 100644
--- a/src/encoded/schemas/complexity_xcorr_quality_metric.json
+++ b/src/encoded/schemas/complexity_xcorr_quality_metric.json
@@ -1,8 +1,8 @@
 {
     "title": "Library complexity and cross-correlation quality metric",
     "description": "Schema for reporting library complexity and cross-correlation ('PCR bottleneck coefficient' and 'phantumpeakqualtools run_spp.R') quality metric",
-    "id": "/profiles/complexity_xcorr_quality_metric.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/complexity_xcorr_quality_metric.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["step_run", "quality_metric_of", "award", "lab"],
     "additionalProperties": false,
diff --git a/src/encoded/schemas/computational_model.json b/src/encoded/schemas/computational_model.json
index a6ae99f2b14..ddd2a0030c7 100644
--- a/src/encoded/schemas/computational_model.json
+++ b/src/encoded/schemas/computational_model.json
@@ -1,8 +1,8 @@
 {
     "title": "Computational Model",
     "description": "Schema for submitting metadata for a computational model set.",
-    "id": "/profiles/computational_model.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/computational_model.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": [ "award", "lab"],
     "identifyingProperties": ["uuid", "accession" , "aliases"],
@@ -20,7 +20,7 @@
         { "$ref": "mixins.json#/documents" },
         { "$ref": "file_set.json#/properties" }
     ],
-    "dependencies": {
+    "dependentSchemas": {
         "status": {
             "oneOf": [
                 {
@@ -145,4 +145,4 @@
     },
     "changelog": "/profiles/changelogs/computational_model.md"
 
-}
\ No newline at end of file
+}
diff --git a/src/encoded/schemas/correlation_quality_metric.json b/src/encoded/schemas/correlation_quality_metric.json
index 25790842da5..106fb04997e 100644
--- a/src/encoded/schemas/correlation_quality_metric.json
+++ b/src/encoded/schemas/correlation_quality_metric.json
@@ -1,8 +1,8 @@
 {
     "title": "Correlation quality metric",
     "description": "Schema for reporting correlation as a quality metric",
-    "id": "/profiles/correlation_quality_metric.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/correlation_quality_metric.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["step_run","quality_metric_of", "award", "lab"],
     "additionalProperties": false,
diff --git a/src/encoded/schemas/cpg_correlation_quality_metric.json b/src/encoded/schemas/cpg_correlation_quality_metric.json
index 5783a00ce06..75a8657e0e7 100644
--- a/src/encoded/schemas/cpg_correlation_quality_metric.json
+++ b/src/encoded/schemas/cpg_correlation_quality_metric.json
@@ -1,8 +1,8 @@
 {
     "title": "CpG correlation quality metric",
     "description": "Schema for reporting the 'CpG Correlation' output as a quality metric",
-    "id": "/profiles/cpg_correlation_quality_metric.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/cpg_correlation_quality_metric.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["step_run","quality_metric_of", "award", "lab"],
     "additionalProperties": false,
diff --git a/src/encoded/schemas/dataset.json b/src/encoded/schemas/dataset.json
index 3e92211c8f2..cfdc505e8d3 100644
--- a/src/encoded/schemas/dataset.json
+++ b/src/encoded/schemas/dataset.json
@@ -1,8 +1,8 @@
 {
     "title": "Dataset",
     "description": "Schema for submitting metadata for a dataset.",
-    "id": "/profiles/dataset.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/dataset.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": [ "award", "lab"],
     "identifyingProperties": ["uuid", "accession" , "aliases"],
diff --git a/src/encoded/schemas/differential_accessibility_series.json b/src/encoded/schemas/differential_accessibility_series.json
index 568d119d20d..11ffd334740 100644
--- a/src/encoded/schemas/differential_accessibility_series.json
+++ b/src/encoded/schemas/differential_accessibility_series.json
@@ -1,8 +1,8 @@
 {
     "title": "Differential accessibility series",
     "description": "Chromatin accessibility data investigating cells sorted based on expression of specific genes.",
-    "id": "/profiles/differential_accessibility_series.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/differential_accessibility_series.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": [ "award", "lab"],
     "identifyingProperties": ["uuid", "accession" , "aliases"],
@@ -21,7 +21,7 @@
         { "$ref": "series.json#/properties" },
         { "$ref": "mixins.json#/submitter_comment" }
     ],
-    "dependencies": {
+    "dependentSchemas": {
         "status": {
             "oneOf": [
                 {
diff --git a/src/encoded/schemas/differentiation_series.json b/src/encoded/schemas/differentiation_series.json
index c2a5b4401e4..5ccf3aeb61c 100644
--- a/src/encoded/schemas/differentiation_series.json
+++ b/src/encoded/schemas/differentiation_series.json
@@ -1,8 +1,8 @@
 {
     "title": "Differentiation series",
     "description": "Experimental data investigating biosamples along a differentiation trajectory.",
-    "id": "/profiles/differentiation_series.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/differentiation_series.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": [ "award", "lab"],
     "identifyingProperties": ["uuid", "accession" , "aliases"],
@@ -21,7 +21,7 @@
         { "$ref": "series.json#/properties" },
         { "$ref": "mixins.json#/submitter_comment" }
     ],
-    "dependencies": {
+    "dependentSchemas": {
         "status": {
             "oneOf": [
                 {
diff --git a/src/encoded/schemas/disease_series.json b/src/encoded/schemas/disease_series.json
index 0baf73b2901..293fe10f845 100644
--- a/src/encoded/schemas/disease_series.json
+++ b/src/encoded/schemas/disease_series.json
@@ -1,8 +1,8 @@
 {
     "title": "Disease series",
     "description": "Experimental data investigating samples grouping guided by an identified disease.",
-    "id": "/profiles/disease_series.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/disease_series.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": [ "award", "lab"],
     "identifyingProperties": ["uuid", "accession" , "aliases"],
@@ -21,7 +21,7 @@
         { "$ref": "series.json#/properties" },
         { "$ref": "mixins.json#/submitter_comment" }
     ],
-    "dependencies": {
+    "dependentSchemas": {
         "status": {
             "oneOf": [
                 {
@@ -335,4 +335,4 @@
         "doi": 1.0
     },
     "changelog": "/profiles/changelogs/disease_series.md"
-}
\ No newline at end of file
+}
diff --git a/src/encoded/schemas/dnase_alignment_quality_metric.json b/src/encoded/schemas/dnase_alignment_quality_metric.json
index b6fc726282c..5564c57ab49 100644
--- a/src/encoded/schemas/dnase_alignment_quality_metric.json
+++ b/src/encoded/schemas/dnase_alignment_quality_metric.json
@@ -1,8 +1,8 @@
 {
     "title": "DNase specific alignment quality alignment",
     "description": "Schema for reporting DNAse seq insert size information and attachments",
-    "id": "/profiles/dnase_alignment_quality_metric.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/dnase_alignment_quality_metric.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["step_run", "award", "lab", "quality_metric_of"],
     "additionalProperties": false,
diff --git a/src/encoded/schemas/dnase_footprinting_quality_metric.json b/src/encoded/schemas/dnase_footprinting_quality_metric.json
index 6ab6e1edb48..d6ab8e69206 100644
--- a/src/encoded/schemas/dnase_footprinting_quality_metric.json
+++ b/src/encoded/schemas/dnase_footprinting_quality_metric.json
@@ -1,8 +1,8 @@
 {
     "title": "DNase footprinting quality metric",
     "description": "Schema for reporting DNase footprinting quality metric",
-    "id": "/profiles/dnase_footprinting_quality_metric.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/dnase_footprinting_quality_metric.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["step_run", "award", "lab", "quality_metric_of"],
     "additionalProperties": false,
diff --git a/src/encoded/schemas/document.json b/src/encoded/schemas/document.json
index 73924bb1498..440187702c1 100644
--- a/src/encoded/schemas/document.json
+++ b/src/encoded/schemas/document.json
@@ -1,8 +1,8 @@
 {
     "title": "Document",
     "description": "Schema for submitting a document file.",
-    "id": "/profiles/document.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/document.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": [ "document_type", "lab", "award"],
     "identifyingProperties": ["uuid","aliases"],
diff --git a/src/encoded/schemas/donor.json b/src/encoded/schemas/donor.json
index e12adab100f..4b8a1273ec5 100644
--- a/src/encoded/schemas/donor.json
+++ b/src/encoded/schemas/donor.json
@@ -2,8 +2,8 @@
     "title": "Donor",
     "description": "Base schema for donors or strains.",
     "comment": "Human donors and model organism strains derive from this base object.",
-    "id": "/profiles/donor.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/donor.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": [ "award", "lab", "organism"],
     "mixinProperties": [
diff --git a/src/encoded/schemas/donor_characterization.json b/src/encoded/schemas/donor_characterization.json
index 1fa64fe60bd..1d01d11fe23 100644
--- a/src/encoded/schemas/donor_characterization.json
+++ b/src/encoded/schemas/donor_characterization.json
@@ -1,8 +1,8 @@
 {
     "title": "Donor characterization",
     "description": "Schema for submitting model organism donor (strain) characterization data",
-    "id": "/profiles/donor_characterization.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/donor_characterization.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": [ "award", "lab", "characterizes", "attachment"],
     "identifyingProperties": ["uuid", "aliases"],
diff --git a/src/encoded/schemas/duplicates_quality_metric.json b/src/encoded/schemas/duplicates_quality_metric.json
index 0b86f2fa9b5..92ecb1a0f43 100644
--- a/src/encoded/schemas/duplicates_quality_metric.json
+++ b/src/encoded/schemas/duplicates_quality_metric.json
@@ -1,8 +1,8 @@
 {
     "title": "Read duplicates quality metric",
     "description": "Schema for reporting duplicates from 'picard' or 'samtools -c' as a quality metric",
-    "id": "/profiles/duplicates_quality_metric.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/duplicates_quality_metric.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["step_run","quality_metric_of", "award", "lab"],
     "additionalProperties": false,
diff --git a/src/encoded/schemas/edwbamstats_quality_metric.json b/src/encoded/schemas/edwbamstats_quality_metric.json
index 630868a95f5..f1858a6d9f0 100644
--- a/src/encoded/schemas/edwbamstats_quality_metric.json
+++ b/src/encoded/schemas/edwbamstats_quality_metric.json
@@ -1,8 +1,8 @@
 {
     "title": "edwbamstats quality metric",
     "description": "Schema for reporting 'edwBamStats' output as a quality metric",
-    "id": "/profiles/edwbamstats_quality_metric.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/edwbamstats_quality_metric.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["step_run","quality_metric_of", "award", "lab"],
     "additionalProperties": false,
diff --git a/src/encoded/schemas/experiment.json b/src/encoded/schemas/experiment.json
index e091102914e..8c2238eafbf 100644
--- a/src/encoded/schemas/experiment.json
+++ b/src/encoded/schemas/experiment.json
@@ -2,8 +2,8 @@
     "title": "Experiment",
     "description": "Schema for submitting metadata for an assay with 1 or more replicates.",
     "comment": "An experiment is a special case of dataset. It includes assay metadata, replicate information and data files.",
-    "id": "/profiles/experiment.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/experiment.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["award", "lab", "assay_term_name", "biosample_ontology"],
     "identifyingProperties": ["uuid", "accession" , "aliases"],
@@ -23,7 +23,7 @@
         { "$ref": "mixins.json#/assay" },
         { "$ref": "mixins.json#/submitter_comment" }
     ],
-    "dependencies": {
+    "dependentSchemas": {
         "status": {
             "oneOf": [
                 {
diff --git a/src/encoded/schemas/experiment_series.json b/src/encoded/schemas/experiment_series.json
index 8d2664d58c0..9d4561956f5 100644
--- a/src/encoded/schemas/experiment_series.json
+++ b/src/encoded/schemas/experiment_series.json
@@ -1,8 +1,8 @@
 {
     "title": "Experiment series",
     "description": "Schema for submitting metadata for a group of experiments which are applying the same assay on the same type of biosample.",
-    "id": "/profiles/experiment_series.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/experiment_series.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["award", "lab", "related_datasets"],
     "identifyingProperties": ["uuid", "accession", "aliases"],
@@ -18,7 +18,7 @@
         { "$ref": "mixins.json#/notes" },
         { "$ref": "mixins.json#/submitter_comment" }
     ],
-    "dependencies": {
+    "dependentSchemas": {
         "status": {
             "oneOf": [
                 {
diff --git a/src/encoded/schemas/file.json b/src/encoded/schemas/file.json
index c7ff99c2f6d..827e93337b1 100644
--- a/src/encoded/schemas/file.json
+++ b/src/encoded/schemas/file.json
@@ -1,8 +1,8 @@
 {
     "title": "Data file",
     "description": "Schema for submitting metadata for a data file.",
-    "id": "/profiles/file.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/file.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "anyOf":[
         {
@@ -168,7 +168,7 @@
             "title": "Encyclopedia version"
         }
     },
-    "dependencies": {
+    "dependentSchemas": {
         "no_file_available":{
             "comment": "md5sum is required for all files unless the file is not available from the portal. file_size is required for files present on portal and have one of the statuses: in progress, revoked, archived or released.",
             "oneOf": [
diff --git a/src/encoded/schemas/file_set.json b/src/encoded/schemas/file_set.json
index 930169de40f..1ad020ffdae 100644
--- a/src/encoded/schemas/file_set.json
+++ b/src/encoded/schemas/file_set.json
@@ -1,8 +1,8 @@
 {
     "title": "File set",
     "description": "Schema for submitting metadata for a file set.",
-    "id": "/profiles/file_set.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/file_set.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": [ "award", "lab"],
     "identifyingProperties": ["uuid", "accession" , "aliases"],
diff --git a/src/encoded/schemas/filtering_quality_metric.json b/src/encoded/schemas/filtering_quality_metric.json
index 6c5373f3050..ea3125d6c60 100644
--- a/src/encoded/schemas/filtering_quality_metric.json
+++ b/src/encoded/schemas/filtering_quality_metric.json
@@ -1,8 +1,8 @@
 {
     "title": "Read filter quality metric",
     "description": "Schema for reporting post alignment read filtering as a quality metric",
-    "id": "/profiles/filtering_quality_metric.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/filtering_quality_metric.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["step_run","quality_metric_of", "award", "lab"],
     "additionalProperties": false,
diff --git a/src/encoded/schemas/fly_donor.json b/src/encoded/schemas/fly_donor.json
index 0d41c65bee5..257cebef756 100644
--- a/src/encoded/schemas/fly_donor.json
+++ b/src/encoded/schemas/fly_donor.json
@@ -2,8 +2,8 @@
     "title": "Fly donor",
     "description": "Schema for submitting a fly strain.",
     "comment": "The fly donor object is meant to represent a strain not an individual fly.",
-    "id": "/profiles/fly_donor.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/fly_donor.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": [ "award", "lab", "organism"],
     "identifyingProperties": ["uuid", "accession", "aliases", "external_ids"],
@@ -26,7 +26,7 @@
         { "$ref": "mixins.json#/submitter_comment" },
         { "$ref": "mixins.json#/schema_version" }
     ],
-    "dependencies": {
+    "dependentSchemas": {
         "parent_strains": {
             "comment": "Parent strains list can contain up to two entries, of strains of the same organism.",
             "properties":{
diff --git a/src/encoded/schemas/functional_characterization_experiment.json b/src/encoded/schemas/functional_characterization_experiment.json
index 688b36b096d..f05ba5e0829 100644
--- a/src/encoded/schemas/functional_characterization_experiment.json
+++ b/src/encoded/schemas/functional_characterization_experiment.json
@@ -2,8 +2,8 @@
     "title": "Functional characterization experiment",
     "description": "Schema for submitting metadata for a functional characterization assay.",
     "comment": "A functional characterization experiment is a special case of dataset. It includes assay metadata, replicate information and data files.",
-    "id": "/profiles/functional_characterization_experiment.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/functional_characterization_experiment.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["award", "lab", "assay_term_name", "biosample_ontology"],
     "identifyingProperties": ["uuid", "accession" , "aliases"],
@@ -23,7 +23,7 @@
         { "$ref": "mixins.json#/assay" },
         { "$ref": "mixins.json#/submitter_comment" }
     ],
-    "dependencies": {
+    "dependentSchemas": {
         "status": {
             "oneOf": [
                 {
@@ -300,9 +300,11 @@
                         ]
                     }
                 },
-                "dependencies": {
-                    "expression_range_minimum": ["expression_range_maximum"],
-                    "expression_range_maximum": ["expression_range_minimum"],
+		"dependentRequired": {
+		    "expression_range_minimum": ["expression_range_maximum"],
+		    "expression_range_maximum": ["expression_range_minimum"]
+		},
+                "dependentSchemas": {
                     "expression_percentile": {
                         "not": {
                             "anyOf": [
diff --git a/src/encoded/schemas/functional_characterization_series.json b/src/encoded/schemas/functional_characterization_series.json
index 77c7302c448..f18435faac8 100644
--- a/src/encoded/schemas/functional_characterization_series.json
+++ b/src/encoded/schemas/functional_characterization_series.json
@@ -1,8 +1,8 @@
 {
     "title": "Functional characterization experiment series",
     "description": "Schema for submitting metadata for functional characterization experiment series.",
-    "id": "/profiles/functional_characterization_series.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/functional_characterization_series.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": [ "award", "lab"],
     "identifyingProperties": ["uuid", "accession" , "aliases"],
@@ -21,7 +21,7 @@
         { "$ref": "series.json#/properties" },
         { "$ref": "mixins.json#/submitter_comment" }
     ],
-    "dependencies": {
+    "dependentSchemas": {
         "status": {
             "oneOf": [
                 {
diff --git a/src/encoded/schemas/gembs_alignment_quality_metric.json b/src/encoded/schemas/gembs_alignment_quality_metric.json
index fd1c3376bdf..dacebde8474 100644
--- a/src/encoded/schemas/gembs_alignment_quality_metric.json
+++ b/src/encoded/schemas/gembs_alignment_quality_metric.json
@@ -1,8 +1,8 @@
 {
     "title": "gemBS alignment quality metric",
     "description": "Schema for gemBS alignment quality metrics",
-    "id": "/profiles/gembs_alignment_quality_metric.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/gembs_alignment_quality_metric.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["step_run","quality_metric_of", "award", "lab"],
     "additionalProperties": false,
diff --git a/src/encoded/schemas/gencode_category_quality_metric.json b/src/encoded/schemas/gencode_category_quality_metric.json
index b55b7428666..6da6eeb1bfd 100644
--- a/src/encoded/schemas/gencode_category_quality_metric.json
+++ b/src/encoded/schemas/gencode_category_quality_metric.json
@@ -1,8 +1,8 @@
 {
     "title": "GENCODE category quality metric",
     "description": "Schema for reporting bulk RNA-seq pipeline GENCODE comprehensive unique category counts",
-    "id": "/profiles/gencode_category_quality_metric.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/gencode_category_quality_metric.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["step_run", "award", "lab", "quality_metric_of"],
     "additionalProperties": false,
diff --git a/src/encoded/schemas/gene.json b/src/encoded/schemas/gene.json
index 59dadb02ccb..d80c218c4c1 100644
--- a/src/encoded/schemas/gene.json
+++ b/src/encoded/schemas/gene.json
@@ -1,8 +1,8 @@
 {
     "title": "Gene",
     "description": "Schema for submitting a gene.",
-    "id": "/profiles/gene.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/gene.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["geneid", "ncbi_entrez_status", "symbol", "dbxrefs", "organism"],
     "identifyingProperties": ["uuid", "geneid"],
@@ -13,7 +13,7 @@
         { "$ref": "mixins.json#/notes" },
         { "$ref": "mixins.json#/standard_status" }
     ],
-    "dependencies": {
+    "dependentSchemas": {
         "locations": {
             "oneOf": [
                 {
diff --git a/src/encoded/schemas/gene_quantification_quality_metric.json b/src/encoded/schemas/gene_quantification_quality_metric.json
index 0b4c86a30dc..8a97809ee9b 100644
--- a/src/encoded/schemas/gene_quantification_quality_metric.json
+++ b/src/encoded/schemas/gene_quantification_quality_metric.json
@@ -1,8 +1,8 @@
 {
     "title": "RNA-seq gene quantification quality metric",
     "description": "Schema for reporting number of genes detected in RNA-seq",
-    "id": "/profiles/gene_quantification_quality_metric.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/gene_quantification_quality_metric.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["step_run","quality_metric_of", "award", "lab"],
     "additionalProperties": false,
diff --git a/src/encoded/schemas/gene_silencing_series.json b/src/encoded/schemas/gene_silencing_series.json
index 1da8a1fac59..f1e2badf7ce 100644
--- a/src/encoded/schemas/gene_silencing_series.json
+++ b/src/encoded/schemas/gene_silencing_series.json
@@ -1,8 +1,8 @@
 {
     "title": "Gene silencing series",
     "description": "Experimental data investigating the effects of knockout or knockdown of genes.",
-    "id": "/profiles/gene_silencing_series.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/gene_silencing_series.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": [ "award", "lab"],
     "identifyingProperties": ["uuid", "accession" , "aliases"],
@@ -21,7 +21,7 @@
         { "$ref": "series.json#/properties" },
         { "$ref": "mixins.json#/submitter_comment" }
     ],
-    "dependencies": {
+    "dependentSchemas": {
         "status": {
             "oneOf": [
                 {
diff --git a/src/encoded/schemas/gene_type_quantification_quality_metric.json b/src/encoded/schemas/gene_type_quantification_quality_metric.json
index 0fa47f537ea..f832f8f720f 100644
--- a/src/encoded/schemas/gene_type_quantification_quality_metric.json
+++ b/src/encoded/schemas/gene_type_quantification_quality_metric.json
@@ -1,8 +1,8 @@
 {
     "title": "RNA-seq gene type quantification quality metric",
     "description": "Schema for reporting number of reads per gene category in RNA-seq. https://www.gencodegenes.org/pages/biotypes.html",
-    "id": "/profiles/gene_type_quantification_quality_metric.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/gene_type_quantification_quality_metric.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["step_run","quality_metric_of", "award", "lab"],
     "additionalProperties": false,
diff --git a/src/encoded/schemas/generic_quality_metric.json b/src/encoded/schemas/generic_quality_metric.json
index fc4cd4f83ce..366c2ca231e 100644
--- a/src/encoded/schemas/generic_quality_metric.json
+++ b/src/encoded/schemas/generic_quality_metric.json
@@ -1,8 +1,8 @@
 {
     "title": "Quality metric",
     "description": "Schema for reporting generic quality metric",
-    "id": "/profiles/generic_quality_metric.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/generic_quality_metric.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["step_run", "quality_metric_of", "name", "award", "lab"],
     "additionalProperties": false,
diff --git a/src/encoded/schemas/genetic_modification.json b/src/encoded/schemas/genetic_modification.json
index 9613082baca..163eb2a59ed 100644
--- a/src/encoded/schemas/genetic_modification.json
+++ b/src/encoded/schemas/genetic_modification.json
@@ -1,8 +1,8 @@
 {
     "title": "Genetic Modification",
     "description": "Schema for submitting information on genetic modification.",
-    "id": "/profiles/genetic_modification.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/genetic_modification.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "anyOf": [
         {
@@ -37,7 +37,7 @@
         { "$ref": "mixins.json#/notes" },
         { "$ref": "mixins.json#/submitter_comment" }
     ],
-    "dependencies": {
+    "dependentSchemas": {
         "purpose": {
             "comment": "Modifications for tagging purposes need to include the introduced_tag property in combination with a target. Modifications for other purposes also need either the site and/or target specified.",
             "oneOf": [
diff --git a/src/encoded/schemas/genetic_modification_characterization.json b/src/encoded/schemas/genetic_modification_characterization.json
index 301ca592ee4..2fad1c0ca7c 100644
--- a/src/encoded/schemas/genetic_modification_characterization.json
+++ b/src/encoded/schemas/genetic_modification_characterization.json
@@ -1,8 +1,8 @@
 {
     "title": "Genetic modification characterization",
     "description": "Schema for submitting genetic modification characterization data.",
-    "id": "/profiles/genetic_modification_characterization.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/genetic_modification_characterization.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": [ "award", "lab", "characterizes", "attachment"],
     "identifyingProperties": ["uuid", "aliases"],
diff --git a/src/encoded/schemas/hic_quality_metric.json b/src/encoded/schemas/hic_quality_metric.json
index cf429e34133..b0381809312 100644
--- a/src/encoded/schemas/hic_quality_metric.json
+++ b/src/encoded/schemas/hic_quality_metric.json
@@ -1,8 +1,8 @@
 {
     "title": "HiC quality metric",
     "description": "HiC quality metrics",
-    "id": "/profiles/hic_quality_metric.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/hic_quality_metric.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["step_run","quality_metric_of", "award", "lab"],
     "additionalProperties": false,
@@ -17,7 +17,7 @@
         { "$ref": "mixins.json#/standard_status"},
         { "$ref": "mixins.json#/assay" }
     ],
-    "dependencies": {
+    "dependentSchemas": {
         "avg_insert_size": {
             "required": ["run_type"],
             "properties": {
diff --git a/src/encoded/schemas/histone_chipseq_quality_metric.json b/src/encoded/schemas/histone_chipseq_quality_metric.json
index f0804e933d2..acb4aa6a6b9 100644
--- a/src/encoded/schemas/histone_chipseq_quality_metric.json
+++ b/src/encoded/schemas/histone_chipseq_quality_metric.json
@@ -1,8 +1,8 @@
 {
     "title": "Histone modification ChIP-seq quality metric",
     "description": "Schema for reporting histone modification ChIP-seq quality metrics",
-    "id": "/profiles/histone_chipseq_quality_metric.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/histone_chipseq_quality_metric.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["step_run","quality_metric_of", "award", "lab"],
     "additionalProperties": false,
diff --git a/src/encoded/schemas/hotspot_quality_metric.json b/src/encoded/schemas/hotspot_quality_metric.json
index 610438a9eac..4fe05d2f9eb 100644
--- a/src/encoded/schemas/hotspot_quality_metric.json
+++ b/src/encoded/schemas/hotspot_quality_metric.json
@@ -1,8 +1,8 @@
 {
     "title": "Hotspot quality metric",
     "description": "Schema for reporting hotspot 'spot.out' as a quality metric",
-    "id": "/profiles/hotspot_quality_metric.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/hotspot_quality_metric.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["step_run","quality_metric_of", "award", "lab"],
     "additionalProperties": false,
diff --git a/src/encoded/schemas/human_donor.json b/src/encoded/schemas/human_donor.json
index ce90a4cb77d..8f97d3b7823 100644
--- a/src/encoded/schemas/human_donor.json
+++ b/src/encoded/schemas/human_donor.json
@@ -2,8 +2,8 @@
     "title": "Human donor",
     "description": "Schema for submitting a human donor.",
     "comment":"This object is meant to be one to one with an individual human.",
-    "id": "/profiles/human_donor.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/human_donor.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": [ "award", "lab", "organism"],
     "identifyingProperties": ["uuid", "accession", "aliases", "external_ids"],
@@ -23,7 +23,7 @@
         { "$ref": "mixins.json#/submitter_comment" },
         { "$ref": "mixins.json#/schema_version" }
     ],
-    "dependencies": {
+    "dependentSchemas": {
         "internal_tags": {
             "comment": "If internal_tags list is initiated, it must contain at least one value.",
             "properties": {
diff --git a/src/encoded/schemas/idr_quality_metric.json b/src/encoded/schemas/idr_quality_metric.json
index 8934259fb91..a7f942e80a6 100644
--- a/src/encoded/schemas/idr_quality_metric.json
+++ b/src/encoded/schemas/idr_quality_metric.json
@@ -1,8 +1,8 @@
 {
     "title": "IDR quality metric",
     "description": "Schema for reporting the 'Irreproducible Discovery Rate' (IDR) statistics",
-    "id": "/profiles/idr_quality_metric.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/idr_quality_metric.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["step_run","quality_metric_of", "award", "lab"],
     "additionalProperties": false,
diff --git a/src/encoded/schemas/idr_summary_quality_metric.json b/src/encoded/schemas/idr_summary_quality_metric.json
index 2f00b992528..ca5c59d9af6 100644
--- a/src/encoded/schemas/idr_summary_quality_metric.json
+++ b/src/encoded/schemas/idr_summary_quality_metric.json
@@ -1,8 +1,8 @@
 {
     "title": "IDR summary quality metric",
     "description": "Schema for reporting the 'Irreproducible Discovery Rate' (IDR) summary quality metric",
-    "id": "/profiles/idr_summary_quality_metric.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/idr_summary_quality_metric.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["step_run","quality_metric_of", "award", "lab"],
     "additionalProperties": false,
diff --git a/src/encoded/schemas/image.json b/src/encoded/schemas/image.json
index cd85ab1751c..9d158876dbc 100644
--- a/src/encoded/schemas/image.json
+++ b/src/encoded/schemas/image.json
@@ -1,8 +1,8 @@
 {
     "title": "Image",
     "description": "Schema for images embedded in portal pages",
-    "id": "/profiles/image.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/image.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": [ "attachment" ],
     "identifyingProperties": ["uuid"],
diff --git a/src/encoded/schemas/lab.json b/src/encoded/schemas/lab.json
index 8317201ef55..702999c6fe4 100644
--- a/src/encoded/schemas/lab.json
+++ b/src/encoded/schemas/lab.json
@@ -1,7 +1,7 @@
 {
     "title": "Lab",
-    "id": "/profiles/lab.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/lab.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["name", "title"],
     "identifyingProperties": ["uuid", "title", "name"],
diff --git a/src/encoded/schemas/library.json b/src/encoded/schemas/library.json
index 61137efd6d0..d992c1154b3 100644
--- a/src/encoded/schemas/library.json
+++ b/src/encoded/schemas/library.json
@@ -1,8 +1,8 @@
 {
     "title": "Library",
     "description": "Schema for submitting a molecular library.",
-    "id": "/profiles/library.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/library.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": [ "award", "lab", "nucleic_acid_term_name"],
     "identifyingProperties": ["uuid","accession", "aliases"],
@@ -27,13 +27,15 @@
             "title": "Status"
         }
     },
-    "dependencies": {
-        "nucleic_acid_starting_quantity_units": ["nucleic_acid_starting_quantity"],
-        "nucleic_acid_starting_quantity": ["nucleic_acid_starting_quantity_units"],
-        "fragmentation_duration_time_units": ["fragmentation_duration_time", "fragmentation_methods"],
-        "fragmentation_duration_time": ["fragmentation_duration_time_units", "fragmentation_methods"],
-        "product_id": ["source"],
-        "lot_id": ["source", "product_id"],
+    "dependentRequired": {
+	"nucleic_acid_starting_quantity_units": ["nucleic_acid_starting_quantity"],
+	"nucleic_acid_starting_quantity": ["nucleic_acid_starting_quantity_units"],
+	"fragmentation_duration_time_units": ["fragmentation_duration_time", "fragmentation_methods"],
+	"fragmentation_duration_time": ["fragmentation_duration_time_units", "fragmentation_methods"],
+	"product_id": ["source"],
+	"lot_id": ["source", "product_id"]
+    },
+    "dependentSchemas": {
         "average_fragment_size": {"not": {"required": ["size_range"]}},
         "size_range": {"not": {"required": ["average_fragment_size"]}},
         "fragment_length_CV": {"not": {"required": ["fragment_length_SD"]}},
diff --git a/src/encoded/schemas/long_read_rna_mapping_quality_metric.json b/src/encoded/schemas/long_read_rna_mapping_quality_metric.json
index 10bec7ef116..809ab453cbf 100644
--- a/src/encoded/schemas/long_read_rna_mapping_quality_metric.json
+++ b/src/encoded/schemas/long_read_rna_mapping_quality_metric.json
@@ -2,8 +2,8 @@
 {
     "title": "long-read RNA-seq mapping quality metric",
     "description": "Schema for reporting long-read RNA-seq pipeline mapping quality metric",
-    "id": "/profiles/long_read_rna_mapping_quality_metric.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/long_read_rna_mapping_quality_metric.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["step_run", "award", "lab", "quality_metric_of", "full_length_non_chimeric_read_count", "mapping_rate"],
     "additionalProperties": false,
diff --git a/src/encoded/schemas/long_read_rna_quantification_quality_metric.json b/src/encoded/schemas/long_read_rna_quantification_quality_metric.json
index f25bac1e0ee..ff35509a220 100644
--- a/src/encoded/schemas/long_read_rna_quantification_quality_metric.json
+++ b/src/encoded/schemas/long_read_rna_quantification_quality_metric.json
@@ -2,8 +2,8 @@
 {
     "title": "long-read RNA-seq quantification quality metric",
     "description": "Schema for reporting long-read RNA-seq pipeline quantification quality metric",
-    "id": "/profiles/long_read_rna_quantification_quality_metric.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/long_read_rna_quantification_quality_metric.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["step_run", "award", "lab", "quality_metric_of", "genes_detected"],
     "additionalProperties": false,
diff --git a/src/encoded/schemas/mad_quality_metric.json b/src/encoded/schemas/mad_quality_metric.json
index fe2cedcb8b0..22430b93890 100644
--- a/src/encoded/schemas/mad_quality_metric.json
+++ b/src/encoded/schemas/mad_quality_metric.json
@@ -1,8 +1,8 @@
 {
     "title": "Mean absolute deviation (MAD) quality metric",
     "description": "Schema for reporting Replicate Concordance Metric using Mean Absolute Deviation (MAD)",
-    "id": "/profiles/mad_quality_metric.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/mad_quality_metric.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["step_run","quality_metric_of", "award", "lab"],
     "additionalProperties": false,
diff --git a/src/encoded/schemas/manatee_donor.json b/src/encoded/schemas/manatee_donor.json
index 8f269d25680..8ad7dd53e7c 100644
--- a/src/encoded/schemas/manatee_donor.json
+++ b/src/encoded/schemas/manatee_donor.json
@@ -2,8 +2,8 @@
     "title": "Manatee donor",
     "description": "Schema for submitting a manatee individual.",
     "comment": "The manatee donor object is meant to represent an individual manatee organism.",
-    "id": "/profiles/manatee_donor.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/manatee_donor.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": [ "award", "lab", "organism"],
     "identifyingProperties": ["uuid", "accession", "aliases", "external_ids"],
@@ -26,7 +26,7 @@
         { "$ref": "mixins.json#/submitter_comment" },
         { "$ref": "mixins.json#/schema_version" }
     ],
-    "dependencies": {
+    "dependentSchemas": {
         "age_units":  {
             "comment":"Age units is required if age is specified as anything but unknown.",
             "required": ["age"],
diff --git a/src/encoded/schemas/matched_set.json b/src/encoded/schemas/matched_set.json
index a8bcb58a966..5abf7be3a7e 100644
--- a/src/encoded/schemas/matched_set.json
+++ b/src/encoded/schemas/matched_set.json
@@ -1,8 +1,8 @@
 {
     "title": "Matched Set",
     "description": "Schema for submitting metadata for a matched set - a collection of experiments with matching properties except for donor.",
-    "id": "/profiles/matched_set.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/matched_set.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": [ "award", "lab"],
     "identifyingProperties": ["uuid", "accession" , "aliases"],
@@ -21,7 +21,7 @@
         { "$ref": "series.json#/properties" },
         { "$ref": "mixins.json#/submitter_comment" }
     ],
-    "dependencies": {
+    "dependentSchemas": {
         "status": {
             "oneOf": [
                 {
diff --git a/src/encoded/schemas/micro_rna_mapping_quality_metric.json b/src/encoded/schemas/micro_rna_mapping_quality_metric.json
index bf0d4a3480f..4934dcecbe4 100644
--- a/src/encoded/schemas/micro_rna_mapping_quality_metric.json
+++ b/src/encoded/schemas/micro_rna_mapping_quality_metric.json
@@ -1,8 +1,8 @@
 {
     "title": "microRNA mapping quality metric",
     "description": "Schema for reporting microRNA pipeline mapping quality metric",
-    "id": "/profiles/micro_rna_mapping_quality_metric.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/micro_rna_mapping_quality_metric.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["step_run", "award", "lab", "quality_metric_of", "aligned_reads"],
     "additionalProperties": false,
diff --git a/src/encoded/schemas/micro_rna_quantification_quality_metric.json b/src/encoded/schemas/micro_rna_quantification_quality_metric.json
index 17083b396df..acd18e1f8b1 100644
--- a/src/encoded/schemas/micro_rna_quantification_quality_metric.json
+++ b/src/encoded/schemas/micro_rna_quantification_quality_metric.json
@@ -1,8 +1,8 @@
 {
     "title": "microRNA quantification quality metric",
     "description": "Schema for reporting microRNA pipeline quantification quality metric",
-    "id": "/profiles/micro_rna_quantification_quality_metric.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/micro_rna_quantification_quality_metric.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["step_run", "award", "lab", "quality_metric_of", "expressed_mirnas"],
     "additionalProperties": false,
diff --git a/src/encoded/schemas/mixins.json b/src/encoded/schemas/mixins.json
index 60dac633c9f..c3c7e4589e2 100644
--- a/src/encoded/schemas/mixins.json
+++ b/src/encoded/schemas/mixins.json
@@ -2,12 +2,12 @@
     "title": "Mixin properties",
     "schema_version": {
         "schema_version": {
-            "title": "Schema version",
-            "description": "The version of the JSON schema that the server uses to validate the object.",
-            "comment":  "Do not submit. The version used to validate the object is set by the server. The default should be set to the current version.",
-            "type": "string",
-            "pattern": "^\\d+(\\.\\d+)*$",
-            "requestMethod": []
+	    "title": "Schema version",
+	    "description": "The version of the JSON schema that the server uses to validate the object.",
+	    "comment":  "Do not submit. The version used to validate the object is set by the server. The default should be set to the current version.",
+	    "type": "string",
+	    "pattern": "^\\d+(\\.\\d+)*$",
+	    "requestMethod": []
         }
     },
     "uuid": {
@@ -19,7 +19,7 @@
             "format": "uuid",
             "serverDefault": "uuid4",
             "permission": "import_items",
-            "requestMethod": "POST"
+            "requestMethod": ["POST"]
         }
     },
     "accession": {
@@ -140,7 +140,7 @@
             "description": "Review of the characterization results by an independent reviewer.",
             "type": "object",
             "additionalProperties": false,
-            "dependencies": {
+            "dependentSchemas": {
                 "status": {
                     "oneOf": [
                          {
diff --git a/src/encoded/schemas/mouse_donor.json b/src/encoded/schemas/mouse_donor.json
index 600d3171554..149de0c1c3a 100644
--- a/src/encoded/schemas/mouse_donor.json
+++ b/src/encoded/schemas/mouse_donor.json
@@ -2,8 +2,8 @@
     "title": "Mouse donor",
     "description": "Schema for submitting a mouse strain.",
     "comment": "The mouse donor object is meant to represent a strain not an individual mouse.",
-    "id": "/profiles/mouse_donor.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/mouse_donor.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": [ "award", "lab", "organism"],
     "identifyingProperties": ["uuid", "accession", "aliases", "external_ids"],
@@ -27,7 +27,7 @@
         { "$ref": "mixins.json#/submitter_comment" },
         { "$ref": "mixins.json#/schema_version" }
     ],
-    "dependencies": {
+    "dependentSchemas": {
         "parent_strains": {
             "comment": "Parent strains list can contain up to two entries, of strains of the same organism.",
             "properties":{
diff --git a/src/encoded/schemas/multiomics_series.json b/src/encoded/schemas/multiomics_series.json
index 1b3e643567e..275bc57dd32 100644
--- a/src/encoded/schemas/multiomics_series.json
+++ b/src/encoded/schemas/multiomics_series.json
@@ -1,8 +1,8 @@
 {
     "title": "Multiomics series",
     "description": "Experimental data investigating biosamples via multiple genomics assays.",
-    "id": "/profiles/multiomics_series.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/multiomics_series.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": [ "award", "lab"],
     "identifyingProperties": ["uuid", "accession" , "aliases"],
@@ -21,7 +21,7 @@
         { "$ref": "series.json#/properties" },
         { "$ref": "mixins.json#/submitter_comment" }
     ],
-    "dependencies": {
+    "dependentSchemas": {
         "status": {
             "oneOf": [
                 {
diff --git a/src/encoded/schemas/organism.json b/src/encoded/schemas/organism.json
index 87af7ae8c5f..5831e239e1d 100644
--- a/src/encoded/schemas/organism.json
+++ b/src/encoded/schemas/organism.json
@@ -1,7 +1,7 @@
 {
     "title": "Organism",
-    "id": "/profiles/organism.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/organism.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["name", "taxon_id", "scientific_name"],
     "identifyingProperties": ["uuid", "name", "taxon_id", "scientific_name"],
diff --git a/src/encoded/schemas/organism_development_series.json b/src/encoded/schemas/organism_development_series.json
index df66804c9e9..751834cec60 100644
--- a/src/encoded/schemas/organism_development_series.json
+++ b/src/encoded/schemas/organism_development_series.json
@@ -1,8 +1,8 @@
 {
     "title": "Organism development series",
     "description": "Experimental data investigating organisms at different developmental stages.",
-    "id": "/profiles/organism_development_series.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/organism_development_series.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": [ "award", "lab"],
     "identifyingProperties": ["uuid", "accession" , "aliases"],
@@ -21,7 +21,7 @@
         { "$ref": "series.json#/properties" },
         { "$ref": "mixins.json#/submitter_comment" }
     ],
-    "dependencies": {
+    "dependentSchemas": {
         "status": {
             "oneOf": [
                 {
diff --git a/src/encoded/schemas/page.json b/src/encoded/schemas/page.json
index cd5fbff8d4f..71abd840e0a 100644
--- a/src/encoded/schemas/page.json
+++ b/src/encoded/schemas/page.json
@@ -1,8 +1,8 @@
 {
     "title": "Page",
     "description": "Schema for a portal page.",
-    "id": "/profiles/page.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/page.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": [
         "name",
@@ -30,7 +30,7 @@
             "$ref": "mixins.json#/attribution"
         }
     ],
-    "dependencies": {
+    "dependentSchemas": {
         "news": {
             "oneOf": [
                 {
diff --git a/src/encoded/schemas/pipeline.json b/src/encoded/schemas/pipeline.json
index 1a0ddb5a409..5ff15d0fec5 100644
--- a/src/encoded/schemas/pipeline.json
+++ b/src/encoded/schemas/pipeline.json
@@ -1,8 +1,8 @@
 {
     "title": "Pipeline",
     "description": "Schema for submitting a series of analysis for a given data type.",
-    "id": "/profiles/pipeline.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/pipeline.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["title", "lab", "award"],
     "identifyingProperties": ["uuid", "aliases", "accession"],
@@ -19,7 +19,7 @@
         { "$ref": "mixins.json#/documents" },
         { "$ref": "mixins.json#/submitter_comment" }
     ],
-    "dependencies": {
+    "dependentSchemas": {
         "assay_term_names": {
              "minItems": 1
         }
diff --git a/src/encoded/schemas/platform.json b/src/encoded/schemas/platform.json
index 6c07ee67f32..d5b49f56044 100644
--- a/src/encoded/schemas/platform.json
+++ b/src/encoded/schemas/platform.json
@@ -1,8 +1,8 @@
 {
     "title": "Platform",
     "description": "Schema for submitting a measurement device.",
-    "id": "/profiles/platform.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/platform.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["term_id"],
     "identifyingProperties": ["uuid", "term_name", "aliases", "term_id"],
diff --git a/src/encoded/schemas/project.json b/src/encoded/schemas/project.json
index fb67acbb898..35a1d915293 100644
--- a/src/encoded/schemas/project.json
+++ b/src/encoded/schemas/project.json
@@ -1,8 +1,8 @@
 {
     "title": "Project",
     "description": "Schema for submitting metadata for a project.",
-    "id": "/profiles/project.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/project.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": [ "award", "lab"],
     "identifyingProperties": ["uuid", "accession" , "aliases"],
@@ -20,7 +20,7 @@
         { "$ref": "dataset.json#/properties" },
         { "$ref": "file_set.json#/properties" }
     ],
-    "dependencies": {
+    "dependentSchemas": {
         "status": {
             "oneOf": [
                 {
diff --git a/src/encoded/schemas/publication.json b/src/encoded/schemas/publication.json
index 52199ce67e8..94dce5094da 100644
--- a/src/encoded/schemas/publication.json
+++ b/src/encoded/schemas/publication.json
@@ -1,8 +1,8 @@
 {
     "title": "Publication",
     "description": "Schema for a publication page.",
-    "id": "/profiles/publication.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/publication.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": [ "title", "award", "lab" ],
     "identifyingProperties": ["uuid", "title"],
diff --git a/src/encoded/schemas/publication_data.json b/src/encoded/schemas/publication_data.json
index 0ce75e526a4..b302d088d6c 100644
--- a/src/encoded/schemas/publication_data.json
+++ b/src/encoded/schemas/publication_data.json
@@ -1,8 +1,8 @@
 {
     "title": "Publication data",
     "description": "Schema for submitting metadata for publication data.",
-    "id": "/profiles/publication_data.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/publication_data.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": [ "award", "lab", "references"],
     "identifyingProperties": ["uuid", "accession" , "aliases"],
@@ -19,7 +19,7 @@
         { "$ref": "dataset.json#/properties" },
         { "$ref": "file_set.json#/properties" }
     ],
-    "dependencies": {
+    "dependentSchemas": {
         "status": {
             "oneOf": [
                 {
diff --git a/src/encoded/schemas/pulse_chase_time_series.json b/src/encoded/schemas/pulse_chase_time_series.json
index e90e25578c1..f4ffca0d106 100644
--- a/src/encoded/schemas/pulse_chase_time_series.json
+++ b/src/encoded/schemas/pulse_chase_time_series.json
@@ -1,8 +1,8 @@
 {
     "title": "Pulse-chase time series",
     "description": "Experimental data investigating biosamples using pulse-chase analysis.",
-    "id": "/profiles/pulse_chase_time_series.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/pulse_chase_time_series.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": [ "award", "lab"],
     "identifyingProperties": ["uuid", "accession" , "aliases"],
@@ -21,7 +21,7 @@
         { "$ref": "series.json#/properties" },
         { "$ref": "mixins.json#/submitter_comment" }
     ],
-    "dependencies": {
+    "dependentSchemas": {
         "status": {
             "oneOf": [
                 {
diff --git a/src/encoded/schemas/quality_metric.json b/src/encoded/schemas/quality_metric.json
index e080deaeaeb..32128f596ea 100644
--- a/src/encoded/schemas/quality_metric.json
+++ b/src/encoded/schemas/quality_metric.json
@@ -1,8 +1,8 @@
 {
     "title": "Quality metric properties",
     "description": "Schema for reporting the specific calculation of an quality metrics",
-    "id": "/profiles/quality_metric.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/quality_metric.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["step_run", "award", "lab"],
     "additionalProperties": false,
diff --git a/src/encoded/schemas/quality_standard.json b/src/encoded/schemas/quality_standard.json
index 68922c3db60..a7349e0b4f5 100644
--- a/src/encoded/schemas/quality_standard.json
+++ b/src/encoded/schemas/quality_standard.json
@@ -1,8 +1,8 @@
 {
     "title": "Quality report and standard",
     "description": "Guidelines for quality reporting and quality standards",
-    "id": "/profiles/quality_standard.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/quality_standard.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["name", "definitions"],
     "additionalProperties": false,
diff --git a/src/encoded/schemas/reference.json b/src/encoded/schemas/reference.json
index 3c7da45b2e2..b4524d95876 100644
--- a/src/encoded/schemas/reference.json
+++ b/src/encoded/schemas/reference.json
@@ -1,8 +1,8 @@
 {
     "title": "Reference",
     "description": "Schema for submitting metadata for a reference set.",
-    "id": "/profiles/reference.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/reference.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": [ "award", "lab"],
     "identifyingProperties": ["uuid", "accession" , "aliases"],
@@ -20,7 +20,7 @@
         { "$ref": "mixins.json#/documents" },
         { "$ref": "file_set.json#/properties" }
     ],
-    "dependencies": {
+    "dependentSchemas": {
         "status": {
             "oneOf": [
                 {
diff --git a/src/encoded/schemas/reference_epigenome.json b/src/encoded/schemas/reference_epigenome.json
index be38fa3be20..1bcaf4fa57e 100644
--- a/src/encoded/schemas/reference_epigenome.json
+++ b/src/encoded/schemas/reference_epigenome.json
@@ -1,8 +1,8 @@
 {
     "title": "Reference epigenome",
     "description": "Schema for submitting metadata for a IHEC-defined reference epigenome.",
-    "id": "/profiles/reference_epigenome.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/reference_epigenome.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": [ "award", "lab"],
     "identifyingProperties": ["uuid", "accession" , "aliases"],
@@ -21,7 +21,7 @@
         { "$ref": "series.json#/properties" },
         { "$ref": "mixins.json#/submitter_comment" }
     ],
-    "dependencies": {
+    "dependentSchemas": {
         "status": {
             "oneOf": [
                 {
diff --git a/src/encoded/schemas/replicate.json b/src/encoded/schemas/replicate.json
index 1b44dbfc631..e7a575ba30f 100644
--- a/src/encoded/schemas/replicate.json
+++ b/src/encoded/schemas/replicate.json
@@ -1,8 +1,8 @@
 {
     "title": "Replicate",
     "description": "Schema for submitting an experimental replicate.",
-    "id": "/profiles/replicate.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/replicate.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["experiment", "biological_replicate_number", "technical_replicate_number"],
     "identifyingProperties": ["uuid","aliases"],
@@ -14,7 +14,7 @@
         { "$ref": "mixins.json#/submitted" },
         { "$ref": "mixins.json#/notes" }
     ],
-    "dependencies": {
+    "dependentRequired": {
         "rbns_protein_concentration": ["rbns_protein_concentration_units"],
         "rbns_protein_concentration_units": ["rbns_protein_concentration"]
     },
diff --git a/src/encoded/schemas/replication_timing_series.json b/src/encoded/schemas/replication_timing_series.json
index a53c61b9087..3dc30c9a8c9 100644
--- a/src/encoded/schemas/replication_timing_series.json
+++ b/src/encoded/schemas/replication_timing_series.json
@@ -1,8 +1,8 @@
 {
     "title": "Replication timing series",
     "description": "Experimental data assessing replication timing phenomena at various phases of the cell cycle.",
-    "id": "/profiles/replication_timing_series.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/replication_timing_series.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": [ "award", "lab"],
     "identifyingProperties": ["uuid", "accession" , "aliases"],
@@ -21,7 +21,7 @@
         { "$ref": "series.json#/properties" },
         { "$ref": "mixins.json#/submitter_comment" }
     ],
-    "dependencies": {
+    "dependentSchemas": {
         "status": {
             "oneOf": [
                 {
diff --git a/src/encoded/schemas/rna_expression.json b/src/encoded/schemas/rna_expression.json
index cb26172e464..d7d4374bebd 100644
--- a/src/encoded/schemas/rna_expression.json
+++ b/src/encoded/schemas/rna_expression.json
@@ -1,8 +1,8 @@
 {
     "title": "RNAExpression",
     "description": "Schema for RNA-seq expression",
-    "id": "/profiles/rna_expression.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/rna_expression.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": [],
     "additionalProperties": false,
diff --git a/src/encoded/schemas/samtools_flagstats_quality_metric.json b/src/encoded/schemas/samtools_flagstats_quality_metric.json
index 4341a8ea9a0..746835c34af 100644
--- a/src/encoded/schemas/samtools_flagstats_quality_metric.json
+++ b/src/encoded/schemas/samtools_flagstats_quality_metric.json
@@ -1,8 +1,8 @@
 {
     "title": "samtools flagstat quality metric",
     "description": "Schema for reporting 'samtools --flagstats' quality metric",
-    "id": "/profiles/samtools_flagstats_quality_metric.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/samtools_flagstats_quality_metric.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["step_run","quality_metric_of", "award", "lab"],
     "additionalProperties": false,
diff --git a/src/encoded/schemas/samtools_stats_quality_metric.json b/src/encoded/schemas/samtools_stats_quality_metric.json
index 5b3bfc18389..5d304449432 100644
--- a/src/encoded/schemas/samtools_stats_quality_metric.json
+++ b/src/encoded/schemas/samtools_stats_quality_metric.json
@@ -1,8 +1,8 @@
 {
     "title": "samtools stats quality metric",
     "description": "Schema for reporting 'samtools --stats' summary as a quality metric",
-    "id": "/profiles/samtools_stats_quality_metric.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/samtools_stats_quality_metric.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["step_run","quality_metric_of", "award", "lab"],
     "additionalProperties": false,
diff --git a/src/encoded/schemas/sc_atac_alignment_quality_metric.json b/src/encoded/schemas/sc_atac_alignment_quality_metric.json
index 6a96e64a5f4..21fa24e7d43 100644
--- a/src/encoded/schemas/sc_atac_alignment_quality_metric.json
+++ b/src/encoded/schemas/sc_atac_alignment_quality_metric.json
@@ -1,8 +1,8 @@
 {
     "title": "scATAC-seq alignment quality metric",
     "description": "Schema for scATAC-seq alignment quality metrics",
-    "id": "/profiles/sc_atac_alignment_quality_metric.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/sc_atac_alignment_quality_metric.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["step_run","quality_metric_of", "award", "lab"],
     "additionalProperties": false,
diff --git a/src/encoded/schemas/sc_atac_analysis_quality_metric.json b/src/encoded/schemas/sc_atac_analysis_quality_metric.json
index e3ecb7994c0..195ee366599 100644
--- a/src/encoded/schemas/sc_atac_analysis_quality_metric.json
+++ b/src/encoded/schemas/sc_atac_analysis_quality_metric.json
@@ -1,8 +1,8 @@
 {
     "title": "scATAC-seq analysis quality metric",
     "description": "Schema for scATAC-seq analysis quality metrics",
-    "id": "/profiles/sc_atac_analysis_quality_metric.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/sc_atac_analysis_quality_metric.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["step_run","quality_metric_of", "award", "lab"],
     "additionalProperties": false,
diff --git a/src/encoded/schemas/sc_atac_counts_summary_quality_metric.json b/src/encoded/schemas/sc_atac_counts_summary_quality_metric.json
index 0c97727ecf6..75e7a72803a 100644
--- a/src/encoded/schemas/sc_atac_counts_summary_quality_metric.json
+++ b/src/encoded/schemas/sc_atac_counts_summary_quality_metric.json
@@ -1,8 +1,8 @@
 {
     "title": "scATAC-seq counts summary quality metric",
     "description": "Schema for scATAC-seq counts summary quality metrics",
-    "id": "/profiles/sc_atac_counts_summary_quality_metric.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/sc_atac_counts_summary_quality_metric.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["step_run","quality_metric_of", "award", "lab"],
     "additionalProperties": false,
diff --git a/src/encoded/schemas/sc_atac_library_complexity_quality_metric.json b/src/encoded/schemas/sc_atac_library_complexity_quality_metric.json
index fe1ac7a3ce6..04d768bc0b5 100644
--- a/src/encoded/schemas/sc_atac_library_complexity_quality_metric.json
+++ b/src/encoded/schemas/sc_atac_library_complexity_quality_metric.json
@@ -1,8 +1,8 @@
 {
     "title": "scATAC-seq library complexity quality metric",
     "description": "Schema for scATAC-seq library complexity quality metrics",
-    "id": "/profiles/sc_atac_library_complexity_quality_metric.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/sc_atac_library_complexity_quality_metric.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["step_run","quality_metric_of", "award", "lab"],
     "additionalProperties": false,
diff --git a/src/encoded/schemas/sc_atac_multiplet_quality_metric.json b/src/encoded/schemas/sc_atac_multiplet_quality_metric.json
index 53ea881033f..5d65f93aebe 100644
--- a/src/encoded/schemas/sc_atac_multiplet_quality_metric.json
+++ b/src/encoded/schemas/sc_atac_multiplet_quality_metric.json
@@ -1,8 +1,8 @@
 {
     "title": "scATAC-seq multiplet quality metric",
     "description": "Schema for scATAC-seq multiplet quality metrics",
-    "id": "/profiles/sc_atac_multiplet_quality_metric.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/sc_atac_multiplet_quality_metric.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["step_run","quality_metric_of", "award", "lab"],
     "additionalProperties": false,
diff --git a/src/encoded/schemas/sc_atac_read_quality_metric.json b/src/encoded/schemas/sc_atac_read_quality_metric.json
index 011c9dd1b70..621960bdbc1 100644
--- a/src/encoded/schemas/sc_atac_read_quality_metric.json
+++ b/src/encoded/schemas/sc_atac_read_quality_metric.json
@@ -1,8 +1,8 @@
 {
     "title": "scATAC-seq read quality metric",
     "description": "Schema for scATAC-seq reads quality metrics",
-    "id": "/profiles/sc_atac_read_quality_metric.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/sc_atac_read_quality_metric.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["step_run","quality_metric_of", "award", "lab"],
     "additionalProperties": false,
diff --git a/src/encoded/schemas/scrna_seq_counts_summary_quality_metric.json b/src/encoded/schemas/scrna_seq_counts_summary_quality_metric.json
index a29323bd209..64b2005a017 100644
--- a/src/encoded/schemas/scrna_seq_counts_summary_quality_metric.json
+++ b/src/encoded/schemas/scrna_seq_counts_summary_quality_metric.json
@@ -1,8 +1,8 @@
 {
     "title": "scRNA-seq counts summary quality metric",
     "description": "Schema for scRNA-seq counts summary quality metric",
-    "id": "/profiles/scrna_seq_counts_summary_quality_metric.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/scrna_seq_counts_summary_quality_metric.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["step_run","quality_metric_of", "award", "lab"],
     "additionalProperties": false,
diff --git a/src/encoded/schemas/segway_quality_metric.json b/src/encoded/schemas/segway_quality_metric.json
index 4bc27e17940..15e976522b8 100644
--- a/src/encoded/schemas/segway_quality_metric.json
+++ b/src/encoded/schemas/segway_quality_metric.json
@@ -1,8 +1,8 @@
 {
     "title": "Segway quality metric",
     "description": "Schema for Segway quality metric",
-    "id": "/profiles/segway_quality_metric.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/segway_quality_metric.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["step_run","quality_metric_of", "award", "lab"],
     "additionalProperties": false,
diff --git a/src/encoded/schemas/series.json b/src/encoded/schemas/series.json
index 9cc895dd23e..d7ae84a67f6 100644
--- a/src/encoded/schemas/series.json
+++ b/src/encoded/schemas/series.json
@@ -1,8 +1,8 @@
 {
     "title": "Series",
     "description": "Schema for submitting metadata for a series.",
-    "id": "/profiles/series.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/series.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": [ "award", "lab"],
     "identifyingProperties": ["uuid", "accession" , "aliases"],
diff --git a/src/encoded/schemas/single_cell_rna_series.json b/src/encoded/schemas/single_cell_rna_series.json
index f2e7fd5e2a9..3d9918ed377 100644
--- a/src/encoded/schemas/single_cell_rna_series.json
+++ b/src/encoded/schemas/single_cell_rna_series.json
@@ -1,8 +1,8 @@
 {
     "title": "Single cell RNA series",
     "description": "Schema for submitting metadata for a single cell RNA experiment series.",
-    "id": "/profiles/single_cell_rna_series.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/single_cell_rna_series.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": [ "award", "lab"],
     "identifyingProperties": ["uuid", "accession" , "aliases"],
@@ -21,7 +21,7 @@
         { "$ref": "series.json#/properties" },
         { "$ref": "mixins.json#/submitter_comment" }
     ],
-    "dependencies": {
+    "dependentSchemas": {
         "status": {
             "oneOf": [
                 {
diff --git a/src/encoded/schemas/single_cell_unit.json b/src/encoded/schemas/single_cell_unit.json
index e8a55942a0b..6cc5713bd9b 100644
--- a/src/encoded/schemas/single_cell_unit.json
+++ b/src/encoded/schemas/single_cell_unit.json
@@ -2,8 +2,8 @@
     "title": "Single Cell Unit",
     "description": "Schema for submitting metadata for a single cell unit.",
     "comment": "A single cell unit is a special case of dataset. It includes assay metadata, replicate information and data files.",
-    "id": "/profiles/single_cell_unit.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/single_cell_unit.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["award", "lab", "assay_term_name", "biosample_ontology"],
     "identifyingProperties": ["uuid", "accession" , "aliases"],
@@ -22,7 +22,7 @@
         { "$ref": "mixins.json#/biosample_ontology" },
         { "$ref": "mixins.json#/submitter_comment" }
     ],
-    "dependencies": {
+    "dependentSchemas": {
         "status": {
             "oneOf": [
                 {
@@ -216,4 +216,4 @@
         "description": 8.0
     },
     "changelog": "/profiles/changelogs/single_cell_unit.md"
-}
\ No newline at end of file
+}
diff --git a/src/encoded/schemas/software.json b/src/encoded/schemas/software.json
index aece9aa8f9c..362e2e4420e 100644
--- a/src/encoded/schemas/software.json
+++ b/src/encoded/schemas/software.json
@@ -1,8 +1,8 @@
 {
     "title": "Software",
     "description": "Schema for submitting analysis software.",
-    "id": "/profiles/software.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/software.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["name", "description", "title", "award", "lab"],
     "additionalProperties": false,
diff --git a/src/encoded/schemas/software_version.json b/src/encoded/schemas/software_version.json
index b4dec45792c..54479c067cd 100644
--- a/src/encoded/schemas/software_version.json
+++ b/src/encoded/schemas/software_version.json
@@ -1,8 +1,8 @@
 {
     "title": "Software version",
     "description": "Schema for submitting version of software.",
-    "id": "/profiles/software_version.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/software_version.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["software"],
     "additionalProperties": false,
diff --git a/src/encoded/schemas/source.json b/src/encoded/schemas/source.json
index 92ef76b37ce..d10a7a7e2e9 100644
--- a/src/encoded/schemas/source.json
+++ b/src/encoded/schemas/source.json
@@ -1,8 +1,8 @@
 {
     "title": "Source",
     "description": "Schema for submitting an originating lab or vendor.",
-    "id": "/profiles/source.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/source.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["name", "title"],
     "identifyingProperties": ["uuid", "name"],
diff --git a/src/encoded/schemas/star_quality_metric.json b/src/encoded/schemas/star_quality_metric.json
index 9b287c81800..99ba80fb603 100644
--- a/src/encoded/schemas/star_quality_metric.json
+++ b/src/encoded/schemas/star_quality_metric.json
@@ -1,8 +1,8 @@
 {
     "title": "STAR quality metric",
     "description": "Schema for reporting the STAR 'Log.Final.out' quality metric",
-    "id": "/profiles/star_quality_metric.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/star_quality_metric.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["step_run","quality_metric_of", "award", "lab"],
     "additionalProperties": false,
diff --git a/src/encoded/schemas/star_solo_quality_metric.json b/src/encoded/schemas/star_solo_quality_metric.json
index f406c63c41c..bc43d4763d5 100644
--- a/src/encoded/schemas/star_solo_quality_metric.json
+++ b/src/encoded/schemas/star_solo_quality_metric.json
@@ -1,8 +1,8 @@
 {
     "title": "STAR solo quality metric",
     "description": "Schema for reporting the STAR solo quality metric",
-    "id": "/profiles/star_solo_quality_metric.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/star_solo_quality_metric.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["step_run","quality_metric_of", "award", "lab", "mode"],
     "additionalProperties": false,
@@ -284,7 +284,7 @@
             }
         }
     },
-    "dependencies": {
+    "dependentSchemas": {
         "mean_gene_per_cell": {
             "required": ["mode"],
             "properties": {
diff --git a/src/encoded/schemas/target.json b/src/encoded/schemas/target.json
index 0323e5e7881..00151762242 100644
--- a/src/encoded/schemas/target.json
+++ b/src/encoded/schemas/target.json
@@ -1,8 +1,8 @@
 {
     "title": "Target",
     "description": "Schema for submitting a target gene.",
-    "id": "/profiles/target.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/target.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["label", "investigated_as"],
     "identifyingProperties": ["uuid", "label-organism.name", "aliases"],
@@ -83,7 +83,7 @@
             }
         }
     ],
-    "dependencies": {
+    "dependentRequired": {
         "modifications": ["genes"]
     },
     "tag_modifications": {
diff --git a/src/encoded/schemas/transgenic_enhancer_experiment.json b/src/encoded/schemas/transgenic_enhancer_experiment.json
index 34142ba9851..eed57374598 100644
--- a/src/encoded/schemas/transgenic_enhancer_experiment.json
+++ b/src/encoded/schemas/transgenic_enhancer_experiment.json
@@ -2,8 +2,8 @@
     "title": "Transgenic enhancer experiment",
     "description": "Schema for submitting metadata for a transgenic enhancer experiment.",
     "comment": "An transgenic enhancer experiment is a special case of dataset. It includes assay metadata.",
-    "id": "/profiles/transgenic_enhancer_experiment.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/transgenic_enhancer_experiment.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["award", "lab", "assay_term_name", "biosample_ontology"],
     "identifyingProperties": ["uuid", "accession" , "aliases"],
@@ -23,7 +23,7 @@
         { "$ref": "mixins.json#/assay" },
         { "$ref": "mixins.json#/submitter_comment" }
     ],
-    "dependencies": {
+    "dependentSchemas": {
         "status": {
             "oneOf": [
                 {
diff --git a/src/encoded/schemas/treatment.json b/src/encoded/schemas/treatment.json
index e8339aaa5ae..8f6fff4b1c0 100644
--- a/src/encoded/schemas/treatment.json
+++ b/src/encoded/schemas/treatment.json
@@ -1,7 +1,7 @@
 {
     "title": "Treatment",
-    "id": "/profiles/treatment.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/treatment.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["treatment_term_name", "treatment_type"],
     "identifyingProperties": ["uuid","aliases"],
@@ -18,7 +18,7 @@
         { "$ref": "mixins.json#/product_id"},
         { "$ref": "mixins.json#/source"}
     ],
-    "dependencies": {
+    "dependentRequired": {
         "temperature": ["temperature_units"],
         "temperature_units": ["temperature"],
         "amount": ["amount_units"],
diff --git a/src/encoded/schemas/treatment_concentration_series.json b/src/encoded/schemas/treatment_concentration_series.json
index 895de1a737b..3eeb2fa4e1f 100644
--- a/src/encoded/schemas/treatment_concentration_series.json
+++ b/src/encoded/schemas/treatment_concentration_series.json
@@ -1,8 +1,8 @@
 {
     "title": "Treatment concentration series",
     "description": "Experimental data investigating the effects of treatment application at various concentrations.",
-    "id": "/profiles/treatment_concentration_series.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/treatment_concentration_series.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": [ "award", "lab"],
     "identifyingProperties": ["uuid", "accession" , "aliases"],
@@ -21,7 +21,7 @@
         { "$ref": "series.json#/properties" },
         { "$ref": "mixins.json#/submitter_comment" }
     ],
-    "dependencies": {
+    "dependentSchemas": {
         "status": {
             "oneOf": [
                 {
diff --git a/src/encoded/schemas/treatment_time_series.json b/src/encoded/schemas/treatment_time_series.json
index bbef2285ab1..6764dd7aebf 100644
--- a/src/encoded/schemas/treatment_time_series.json
+++ b/src/encoded/schemas/treatment_time_series.json
@@ -1,8 +1,8 @@
 {
     "title": "Treatment time series",
     "description": "Experimental data investigating the effects of treatment application at varying durations.",
-    "id": "/profiles/treatment_time_series.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/treatment_time_series.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": [ "award", "lab"],
     "identifyingProperties": ["uuid", "accession" , "aliases"],
@@ -21,7 +21,7 @@
         { "$ref": "series.json#/properties" },
         { "$ref": "mixins.json#/submitter_comment" }
     ],
-    "dependencies": {
+    "dependentSchemas": {
         "status": {
             "oneOf": [
                 {
diff --git a/src/encoded/schemas/trimming_quality_metric.json b/src/encoded/schemas/trimming_quality_metric.json
index 0f6bc83f35a..6b2a382afe0 100644
--- a/src/encoded/schemas/trimming_quality_metric.json
+++ b/src/encoded/schemas/trimming_quality_metric.json
@@ -1,8 +1,8 @@
 {
     "title": "trim-adapters-illumina quality metric",
     "description": "Schema for reporting trimming from 'trim-adapters-illumina' as a quality metric",
-    "id": "/profiles/trimming_quality_metric.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/trimming_quality_metric.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": ["step_run","quality_metric_of", "award", "lab"],
     "additionalProperties": false,
diff --git a/src/encoded/schemas/ucsc_browser_composite.json b/src/encoded/schemas/ucsc_browser_composite.json
index f2830b94dfb..551218260a5 100644
--- a/src/encoded/schemas/ucsc_browser_composite.json
+++ b/src/encoded/schemas/ucsc_browser_composite.json
@@ -1,8 +1,8 @@
 {
     "title": "UCSC browser composite",
     "description": "Schema for submitting metadata for a composite as defined by the UCSC Genome Browser.",
-    "id": "/profiles/ucsc_browser_composite.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/ucsc_browser_composite.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": [ "award", "lab"],
     "identifyingProperties": ["uuid", "accession" , "aliases"],
@@ -20,7 +20,7 @@
         { "$ref": "dataset.json#/properties" },
         { "$ref": "file_set.json#/properties" }
     ],
-    "dependencies": {
+    "dependentSchemas": {
         "status": {
             "oneOf": [
                 {
diff --git a/src/encoded/schemas/user.json b/src/encoded/schemas/user.json
index 345ac45f791..71abcd4905a 100644
--- a/src/encoded/schemas/user.json
+++ b/src/encoded/schemas/user.json
@@ -1,7 +1,7 @@
 {
     "title": "User",
-    "id": "/profiles/user.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/user.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": [ "email", "first_name", "last_name"],
     "identifyingProperties": ["uuid", "email"],
diff --git a/src/encoded/schemas/worm_donor.json b/src/encoded/schemas/worm_donor.json
index 41d154c1aa0..ee45c5a856d 100644
--- a/src/encoded/schemas/worm_donor.json
+++ b/src/encoded/schemas/worm_donor.json
@@ -2,8 +2,8 @@
     "title": "Worm donor",
     "description": "Schema for submitting a worm strain.",
     "comment": "The worm donor object is meant to represent a strain not an individual worm.",
-    "id": "/profiles/worm_donor.json",
-    "$schema": "http://json-schema.org/draft-04/schema#",
+    "$id": "/profiles/worm_donor.json",
+    "$schema": "https://json-schema.org/draft/2020-12/schema",
     "type": "object",
     "required": [ "award", "lab", "organism"],
     "identifyingProperties": ["uuid", "accession", "aliases", "external_ids"],
@@ -26,7 +26,7 @@
         { "$ref": "mixins.json#/submitter_comment" },
         { "$ref": "mixins.json#/schema_version" }
     ],
-    "dependencies": {
+    "dependentSchemas": {
         "parent_strains": {
             "comment": "Parent strains list can contain up to two entries, of strains of the same organism.",
             "properties":{
diff --git a/src/encoded/server_defaults.py b/src/encoded/server_defaults.py
index 6e11f0778b8..5c22877f21b 100644
--- a/src/encoded/server_defaults.py
+++ b/src/encoded/server_defaults.py
@@ -1,5 +1,5 @@
 from datetime import datetime
-from jsonschema_serialize_fork import NO_DEFAULT
+from snovault.schema_validation import NO_DEFAULT
 from pyramid.threadlocal import get_current_request
 from string import (
     digits,
@@ -36,7 +36,6 @@ def userid(instance, subschema):
 
 @server_default
 def now(instance, subschema):
-    # from jsonschema_serialize_fork date-time format requires a timezone
     return datetime.utcnow().isoformat() + '+00:00'
 
 
diff --git a/src/encoded/static/components/schema.js b/src/encoded/static/components/schema.js
index c4601a3c17c..7e63e845c60 100644
--- a/src/encoded/static/components/schema.js
+++ b/src/encoded/static/components/schema.js
@@ -26,7 +26,7 @@ const excludedTerms = [
     'mixinProperties',
     'title',
     'description',
-    'id',
+    '$id',
     '$schema',
     'facets',
     'columns',
@@ -588,7 +588,7 @@ const SchemaPage = (props) => {
     const { title } = context;
 
     // The schema id is a path to the schema's JSON. Convert that to just the schema name.
-    const schemaName = schemaIdToName(context.id);
+    const schemaName = schemaIdToName(context.$id);
 
     // Set up the "breadcrumbs" (sneer quotes because it's really just a link to /profiles/).
     // If schemaName happened to be null (which it realistically can't), <BreadCrumbs> would
@@ -674,8 +674,8 @@ const AllSchemasPage = (props, reactContext) => {
                             // `objectName` is the @type of each objects e.g. GeneticModification
                             // `schemaName` is the system name of the objects e.g. genetic_modification
                             // `schemaPath` is the schema page path e.g. /profiles/genetic_modification
-                            const schemaName = schemaIdToName(context[objectName].id);
-                            const schemaPath = schemaIdToPage(context[objectName].id);
+                            const schemaName = schemaIdToName(context[objectName].$id);
+                            const schemaPath = schemaIdToPage(context[objectName].$id);
 
                             return (
                                 <div className="schema-list__item" key={objectName}>
diff --git a/src/encoded/tests/test_auth0.py b/src/encoded/tests/test_auth0.py
index 9a4024b2c69..78b6573732f 100644
--- a/src/encoded/tests/test_auth0.py
+++ b/src/encoded/tests/test_auth0.py
@@ -3,7 +3,7 @@
 from unittest import mock
 from snovault import COLLECTIONS		
 import encoded.auth0 as auth0
-from jsonschema_serialize_fork.exceptions import ValidationError
+from jsonschema.exceptions import ValidationError
 from pyramid.httpexceptions import (
     HTTPBadRequest,
     HTTPInternalServerError,
diff --git a/src/encoded/tests/test_permissions.py b/src/encoded/tests/test_permissions.py
index 14b55c6b600..3ebc314c560 100644
--- a/src/encoded/tests/test_permissions.py
+++ b/src/encoded/tests/test_permissions.py
@@ -71,6 +71,81 @@ def test_submitter_post_update_experiment(submitter_testapp, lab, award, cell_fr
     submitter_testapp.patch_json(location, {'description': 'My experiment'}, status=200)
 
 
+def test_submitter_put_update_experiment(submitter_testapp, lab, award, cell_free):
+    experiment = {
+        'lab': lab['@id'],
+        'award': award['@id'],
+        'assay_term_name': 'ChIA-PET',
+        'biosample_ontology': cell_free['uuid']
+    }
+    res = submitter_testapp.post_json('/experiment', experiment, status=201)
+    location = res.location
+    created_experiment = submitter_testapp.get(location).json
+    experiment['assay_term_name'] = 'RNA-seq'
+    experiment['accession'] = created_experiment['accession']
+    submitter_testapp.put_json(location, experiment, status=200)
+    updated_experiment = submitter_testapp.get(location).json
+    for key in ['uuid', 'accession', 'submitted_by']:
+        assert created_experiment[key] == updated_experiment[key], f'{key} does not match after update'
+
+
+def test_submitter_patch_date_created(submitter_testapp, lab, award, cell_free):
+    experiment = {
+        'lab': lab['@id'],
+        'award': award['@id'],
+        'assay_term_name': 'ChIA-PET',
+        'biosample_ontology': cell_free['uuid']
+    }
+    res = submitter_testapp.post_json('/experiment', experiment, status=201)
+    location = res.location
+    created_experiment = submitter_testapp.get(location).json
+    submitter_testapp.patch_json(
+        location,
+        {'date_created': '2022-02-04T04:05:41.045578+00:00'},
+        status=422
+    )
+
+
+def test_submitter_put_date_created(submitter_testapp, lab, award, cell_free):
+    experiment = {
+        'lab': lab['@id'],
+        'award': award['@id'],
+        'assay_term_name': 'ChIA-PET',
+        'biosample_ontology': cell_free['uuid']
+    }
+    res = submitter_testapp.post_json('/experiment', experiment, status=201)
+    location = res.location
+    created_experiment = submitter_testapp.get(location).json
+    experiment['uuid'] = created_experiment['uuid']
+    experiment['accession'] = created_experiment['accession']
+    experiment['date_created'] = '2022-02-04T04:05:41.045578+00:00'
+    submitter_testapp.put_json(
+        location,
+        experiment,
+        status=422
+    )
+
+
+def test_submitter_patch_update_experiment(submitter_testapp, testapp, lab, award, cell_free):
+    experiment = {
+        'lab': lab['@id'],
+        'award': award['@id'],
+        'assay_term_name': 'ChIA-PET',
+        'biosample_ontology': cell_free['uuid']
+    }
+    res = submitter_testapp.post_json('/experiment', experiment, status=201)
+    location = res.location
+    created_experiment = submitter_testapp.get(location).json
+    submitter_testapp.patch_json(location, {'assay_term_name': 'RNA-seq'}, status=200)
+    updated_experiment = submitter_testapp.get(location).json
+    for key in ['uuid', 'accession', 'date_created', 'submitted_by']:
+        assert created_experiment[key] == updated_experiment[key], f'{key} does not match after update'
+    testapp.patch_json(location, {'assay_term_name': 'ChIA-PET'}, status=200)
+    updated_experiment = testapp.get(location).json
+    for key in ['uuid', 'accession', 'date_created', 'submitted_by']:
+        assert created_experiment[key] == updated_experiment[key], f'{key} does not match after update'
+
+
 def test_submitter_post_other_lab(submitter_testapp, other_lab, award, cell_free):
     experiment = {'lab': other_lab['@id'],
                   'award': award['@id'],
diff --git a/src/encoded/tests/test_post_put_patch.py b/src/encoded/tests/test_post_put_patch.py
index 4d70f85959f..47422d64c4c 100644
--- a/src/encoded/tests/test_post_put_patch.py
+++ b/src/encoded/tests/test_post_put_patch.py
@@ -217,7 +217,10 @@ def test_put_object_child_validation(content_with_child, testapp):
         }]
     }
     res = testapp.put_json(content_with_child['@id'], edit, status=422)
-    assert res.json['errors'][0]['name'] == [u'reverse', 0, u'target']
+    assert ['reverse', 0, 'target'] in [
+        x['name']
+        for x in res.json['errors']
+    ]
 
 
 def test_put_object_validates_child_references(content_with_child, testapp):
diff --git a/src/encoded/tests/test_schema_antibody_characterization.py b/src/encoded/tests/test_schema_antibody_characterization.py
index 41956d5c55e..e3ecdf9f305 100644
--- a/src/encoded/tests/test_schema_antibody_characterization.py
+++ b/src/encoded/tests/test_schema_antibody_characterization.py
@@ -32,11 +32,12 @@ def test_no_attachment(testapp, antibody_characterization):
 def test_antibody_characterization_exemption_no_explanation(testapp,
                                                             antibody_characterization,
                                                             document,
+                                                            wrangler,
                                                             k562):
     antibody_characterization['characterization_reviews'] = [{"organism": "human", "lane": 2,
                                                               "biosample_ontology": k562['uuid'],
                                                               "lane_status":
                                                               "exempt from standards"}]
-    antibody_characterization['documents'] = [document]
-    antibody_characterization['reviewed_by'] = '81a6cc12-2847-4e2e-8f2c-f566699eb29e'
+    antibody_characterization['documents'] = [document['@id']]
+    antibody_characterization['reviewed_by'] = wrangler['@id']
     testapp.post_json('/antibody_characterization', antibody_characterization, status=422)
diff --git a/src/encoded/tests/test_schema_library.py b/src/encoded/tests/test_schema_library.py
index 295d772a067..9dac01bc761 100644
--- a/src/encoded/tests/test_schema_library.py
+++ b/src/encoded/tests/test_schema_library.py
@@ -144,7 +144,7 @@ def test_library_biosample_and_mixed_biosample(testapp, library, biosample_1, bi
     testapp.post_json('/library', library, status=201)
     library.update({'mixed_biosamples': [biosample_1['@id'], biosample_2['@id']]})
     testapp.post_json('/library', library, status=201)
-    library.update({'biosample': biosample_2})
+    library.update({'biosample': biosample_2['@id']})
     testapp.post_json('/library', library, status=422)
 
 
diff --git a/src/encoded/tests/test_views.py b/src/encoded/tests/test_views.py
index 761e2133da2..3a9ad75af1e 100644
--- a/src/encoded/tests/test_views.py
+++ b/src/encoded/tests/test_views.py
@@ -323,9 +323,9 @@ def test_index_data_workbook(workbook, testapp, indexer_testapp, item_type):
 
 @pytest.mark.parametrize('item_type', TYPE_LENGTH)
 def test_profiles(testapp, item_type):
-    from jsonschema_serialize_fork import Draft4Validator
+    from jsonschema import Draft202012Validator
     res = testapp.get('/profiles/%s.json' % item_type).maybe_follow(status=200)
-    errors = Draft4Validator.check_schema(res.json)
+    errors = Draft202012Validator.check_schema(res.json)
     assert not errors
 
 
diff --git a/src/encoded/tests/testing_views.py b/src/encoded/tests/testing_views.py
index 4ef1244e802..523b1bf5f94 100644
--- a/src/encoded/tests/testing_views.py
+++ b/src/encoded/tests/testing_views.py
@@ -249,7 +249,7 @@ class TestingDependencies(Item):
     item_type = 'testing_dependencies'
     schema = {
         'type': 'object',
-        'dependencies': {
+        'dependentRequired': {
             'dep1': ['dep2'],
             'dep2': ['dep1'],
         },