diff --git a/requirements.txt b/requirements.txt
index 7719a70f..e111479b 100644
--- a/requirements.txt
+++ b/requirements.txt
@@ -4,16 +4,16 @@ pyyaml==6.0.2
 fhir.resources==8.0.0
 sympy==1.13.3
 pandas==2.2.3
-psycopg[binary]==3.2.6
+psycopg[binary]==3.2.8
 sqlalchemy==2.0.40
-pydantic==2.11.2
-pydantic-settings==2.8.1
-uvicorn[standard]==0.34.0
+pydantic==2.11.4
+pydantic-settings==2.9.1
+uvicorn[standard]==0.34.2
 fastapi==0.115.12
-pendulum==3.0.0
+pendulum==3.1.0
 networkx==3.4.2
 numpy==2.2.4
 pytz==2025.2
 cython==3.0.12
-setuptools==78.1.0
+setuptools==80.4.0
 sortedcontainers==2.4.0