diff --git a/cpp/src/arrow/flight/sql/odbc/CMakeLists.txt b/cpp/src/arrow/flight/sql/odbc/CMakeLists.txt
index d84f49340069..c33374df9c49 100644
--- a/cpp/src/arrow/flight/sql/odbc/CMakeLists.txt
+++ b/cpp/src/arrow/flight/sql/odbc/CMakeLists.txt
@@ -99,9 +99,10 @@ if(ARROW_FLIGHT_SQL_ODBC_INSTALLER)
 
   set(CPACK_RESOURCE_FILE_LICENSE
       "${CMAKE_CURRENT_SOURCE_DIR}/../../../../../../LICENSE.txt")
-  # Tentative version 1.0.0 (patch version is not set)
+  # Tentative version 1.0.0
   set(CPACK_PACKAGE_VERSION_MAJOR "1")
   set(CPACK_PACKAGE_VERSION_MINOR "0")
+  set(CPACK_PACKAGE_VERSION_PATCH "0")
 
   set(CPACK_PACKAGE_NAME "Apache Arrow Flight SQL ODBC")
   set(CPACK_PACKAGE_VENDOR "Apache Arrow")
@@ -115,13 +116,26 @@ if(ARROW_FLIGHT_SQL_ODBC_INSTALLER)
             DESTINATION bin
             COMPONENT flight_sql_odbc_lib
             FILES_MATCHING
-            PATTERN "*.dll"
-            PATTERN "arrow_flight_testing.dll" EXCLUDE
-            PATTERN "arrow_testing.dll" EXCLUDE
-            PATTERN "gflags.dll" EXCLUDE
-            PATTERN "gmock.dll" EXCLUDE
-            PATTERN "gtest.dll" EXCLUDE
-            PATTERN "gtest_main.dll" EXCLUDE)
+            # Use regex for dll name patterns with versions
+            PATTERN "abseil_dll.dll"
+            PATTERN "arrow.dll"
+            PATTERN "arrow_compute.dll"
+            PATTERN "arrow_flight.dll"
+            PATTERN "arrow_flight_sql.dll"
+            PATTERN "arrow_flight_sql_odbc.dll"
+            PATTERN "boost_locale*.dll"
+            PATTERN "cares.dll"
+            PATTERN "libcrypto*.dll"
+            PATTERN "libprotobuf.dll"
+            PATTERN "libssl*.dll"
+            PATTERN "re2.dll"
+            PATTERN "utf8proc.dll"
+            PATTERN "zlib1.dll")
+
+    set(CPACK_WIX_EXTRA_SOURCES
+        "${CMAKE_CURRENT_SOURCE_DIR}/install/arrow-flight-sql-odbc.wxs")
+    set(CPACK_WIX_PATCH_FILE
+        "${CMAKE_CURRENT_SOURCE_DIR}/install/arrow-flight-sql-odbc-patch.xml")
   endif()
 
   get_cmake_property(CPACK_COMPONENTS_ALL COMPONENTS)
diff --git a/cpp/src/arrow/flight/sql/odbc/README b/cpp/src/arrow/flight/sql/odbc/README
index 04749d9b859b..da9857b7ecca 100644
--- a/cpp/src/arrow/flight/sql/odbc/README
+++ b/cpp/src/arrow/flight/sql/odbc/README
@@ -17,3 +17,10 @@ After the build succeeds, the ODBC DLL will be located in
 
 If the registration is successful, then Apache Arrow Flight SQL ODBC Driver 
 should show as an available ODBC driver in the x64 ODBC Driver Manager.
+
+Steps to Generate Windows Installer
+1. Build with  `ARROW_FLIGHT_SQL_ODBC=ON` and `ARROW_FLIGHT_SQL_ODBC_INSTALLER=ON`.
+2. `cd` to `build` folder.
+3. Run `cpack`. 
+
+If the generation is successful, you will find `Apache Arrow Flight SQL ODBC-<version>-win64.msi` generated under the `build` folder.
diff --git a/cpp/src/arrow/flight/sql/odbc/install/arrow-flight-sql-odbc-patch.xml b/cpp/src/arrow/flight/sql/odbc/install/arrow-flight-sql-odbc-patch.xml
new file mode 100644
index 000000000000..f1a63ce5d3bb
--- /dev/null
+++ b/cpp/src/arrow/flight/sql/odbc/install/arrow-flight-sql-odbc-patch.xml
@@ -0,0 +1,22 @@
+<!--
+  Licensed to the Apache Software Foundation (ASF) under one or more
+  contributor license agreements.  See the NOTICE file distributed with
+  this work for additional information regarding copyright ownership.
+  The ASF licenses this file to You under the Apache License, Version 2.0
+  (the "License"); you may not use this file except in compliance with
+  the License.  You may obtain a copy of the License at
+
+       http://www.apache.org/licenses/LICENSE-2.0
+
+  Unless required by applicable law or agreed to in writing, software
+  distributed under the License is distributed on an "AS IS" BASIS,
+  WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+  See the License for the specific language governing permissions and
+  limitations under the License.
+-->
+
+<CPackWiXPatch>
+    <CPackWiXFragment Id="#PRODUCTFEATURE">
+        <ComponentRef Id="ODBCRegistryEntries"/>
+    </CPackWiXFragment>
+</CPackWiXPatch>
diff --git a/cpp/src/arrow/flight/sql/odbc/install/arrow-flight-sql-odbc.wxs b/cpp/src/arrow/flight/sql/odbc/install/arrow-flight-sql-odbc.wxs
new file mode 100644
index 000000000000..bd0216aa7669
--- /dev/null
+++ b/cpp/src/arrow/flight/sql/odbc/install/arrow-flight-sql-odbc.wxs
@@ -0,0 +1,37 @@
+<?xml version="1.0" encoding="windows-1252"?>
+
+<!--
+  Licensed to the Apache Software Foundation (ASF) under one or more
+  contributor license agreements.  See the NOTICE file distributed with
+  this work for additional information regarding copyright ownership.
+  The ASF licenses this file to You under the Apache License, Version 2.0
+  (the "License"); you may not use this file except in compliance with
+  the License.  You may obtain a copy of the License at
+
+       http://www.apache.org/licenses/LICENSE-2.0
+
+  Unless required by applicable law or agreed to in writing, software
+  distributed under the License is distributed on an "AS IS" BASIS,
+  WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+  See the License for the specific language governing permissions and
+  limitations under the License.
+-->
+
+<Wix xmlns="http://wixtoolset.org/schemas/v4/wxs">
+  <Fragment>
+  <DirectoryRef Id="TARGETDIR">
+      <Component Id="ODBCRegistryEntries" Guid="C348B9F7-5E8D-415D-A001-D92F2D4EA013">
+          <RegistryValue Root='HKLM' Key='Software\ODBC\ODBCINST.INI\ODBC Drivers' Name='Apache Arrow Flight SQL ODBC Driver' Type='string' Value='Installed'/>
+
+          <RegistryKey Root="HKLM"
+                      Key="Software\ODBC\ODBCINST.INI\Apache Arrow Flight SQL ODBC Driver">
+                <!-- CM_FP_flight_sql_odbc_lib.bin.arrow_flight_sql_odbc.dll is a generated variable value from build\_CPack_Packages\win64\WIX\files.wxs -->
+                <RegistryValue Type="string" Name="DriverODBCVer" Value="03.00"/>
+                <RegistryValue Type="string" Name="Driver" Value="[#CM_FP_flight_sql_odbc_lib.bin.arrow_flight_sql_odbc.dll]"/>
+                <RegistryValue Type="string" Name="Setup" Value="[#CM_FP_flight_sql_odbc_lib.bin.arrow_flight_sql_odbc.dll]"/>
+                <RegistryValue Type="integer" Name="UsageCount" Value="1"/>
+          </RegistryKey>
+      </Component>
+  </DirectoryRef>
+  </Fragment>
+</Wix>